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Immunology

D-Index
75
Citations
17343
World Ranking
2005
National Ranking
138

Overview

Matthias J. Reddehase is affiliated with Johannes Gutenberg University of Mainz in Germany and has contributed extensively to the fields of Medicine and Immunology and Microbiology. Their work primarily centers on cytomegalovirus and herpesvirus research, along with studies in immune cell function and interaction.

Their research spans several interconnected areas including T-cell and B-cell immunology, herpesvirus infections and treatments, parvovirus B19 infection studies, Toxoplasma gondii research studies, and investigations into mast cells and histamine.

Their recent papers include the following:

  • Consequence of Histoincompatibility beyond GvH-Reaction in Cytomegalovirus Disease Associated with Allogeneic Hematopoietic Cell Transplantation: Change of Paradigm, 2021, Viruses
  • Stochastic Episodes of Latent Cytomegalovirus Transcription Drive CD8 T-Cell "Memory Inflation" and Avoid Immune Evasion, 2021, Frontiers in Immunology
  • Revisiting CD8 T-cell 'Memory Inflation': New Insights with Implications for Cytomegaloviruses as Vaccine Vectors, 2020, Vaccines
  • Cytomegalovirus-Associated Inhibition of Hematopoiesis Is Preventable by Cytoimmunotherapy With Antiviral CD8 T Cells, 2020, Frontiers in Cellular and Infection Microbiology
  • Insufficient Antigen Presentation Due to Viral Immune Evasion Explains Lethal Cytomegalovirus Organ Disease After Allogeneic Hematopoietic Cell Transplantation, 2020, Frontiers in Cellular and Infection Microbiology

Matthias J. Reddehase frequently publishes in several venues, including:

  • Frontiers in Cellular and Infection Microbiology
  • Frontiers in Immunology
  • Viruses
  • bioRxiv (Cold Spring Harbor Laboratory)
  • PLoS Pathogens

Frequent co-authors working alongside Matthias J. Reddehase include:

  • Niels A. W. Lemmermann
  • Rafaela Holtappels
  • Sara Becker
  • Jürgen Podlech
  • Kirsten Freitag

The scientist's work is rooted in the subfields of epidemiology, immunology, infectious diseases, parasitology, and hematology. This broad range of study supports their focus on antiviral immune mechanisms and the pathogenesis of cytomegalovirus-related diseases, particularly in the context of hematopoietic cell transplantation.

Best Publications

  • Site-restricted persistent cytomegalovirus infection after selective long-term depletion of CD4+ T lymphocytes.

    Stipan Jonjic;Wolfgang Mutter;Frank Weiland;Matthias J. Reddehase

  • CD8-positive T lymphocytes specific for murine cytomegalovirus immediate-early antigens mediate protective immunity.

    Matthias J. Reddehase;Wolfgang Mutter;Konrad Münch;Hans-Jörg Bühring

  • Interstitial murine cytomegalovirus pneumonia after irradiation: characterization of cells that limit viral replication during established infection of the lungs.

    Matthias J. Reddehase;Frank Weiland;Konrad Münch;Stipan Jonjic

  • A pentapeptide as minimal antigenic determinant for MHC class I-restricted T lymphocytes.

    Matthias J. Reddehase;Jonathan B. Rothbard;Ulrich H. Koszinowski

  • Efficient processing of an antigenic sequence for presentation by MHC class I molecules depends on its neighboring residues in the protein.

    Margarita Del Val;Hans-Jürgen Schlicht;Thomas Ruppert;Matthias J. Reddehase

  • Antigens and immunoevasins: opponents in cytomegalovirus immune surveillance.

    Matthias J. Reddehase

  • Structure of the gene of tum- transplantation antigen P91A: the mutated exon encodes a peptide recognized with Ld by cytolytic T cells.

    Christophe Lurquin;Christophe Lurquin;Aline Van Pel;Aline Van Pel;Bernard Mariamé;Bernard Mariamé;Etienne De Plaen;Etienne De Plaen

  • Enrichment of immediate-early 1 (m123/pp89) peptide-specific CD8 T cells in a pulmonary CD62L(lo) memory-effector cell pool during latent murine cytomegalovirus infection of the lungs.

    Rafaela Holtappels;Marcus-Folker Pahl-Seibert;Doris Thomas;Matthias J. Reddehase

  • The Conditions of Primary Infection Define the Load of Latent Viral Genome in Organs and the Risk of Recurrent Cytomegalovirus Disease

    Matthias J. Reddehase;Monika Balthesen;Maria Rapp;Stipan Jonjic

  • CD8 T Cells Control Cytomegalovirus Latency by Epitope-Specific Sensing of Transcriptional Reactivation

    Christian O. Simon;Rafaela Holtappels;Hanna-Mari Tervo;Verena Böhm

  • Major Histocompatibility Complex Class I Allele-specific Cooperative and Competitive Interactions between Immune Evasion Proteins of Cytomegalovirus

    Markus Wagner;Anja Gutermann;Jürgen Podlech;Matthias J. Reddehase

  • Simultaneous expression of CD4 and CD8 antigens by a substantial proportion of resting porcine T lymphocytes

    Armin Saalmüller;Matthias J. Reddehase;Hans-Jörg Bühring;Stipan Jonjić

  • Significance of herpesvirus immediate early gene expression in cellular immunity to cytomegalovirus infection

    Matthias J. Reddehase;Ulrich H. Koszinowski

  • Latency versus persistence or intermittent recurrences: evidence for a latent state of murine cytomegalovirus in the lungs.

    S Kurz;H P Steffens;A Mayer;J R Harris

  • Mouse models of cytomegalovirus latency: overview

    Matthias J Reddehase;Jürgen Podlech;Natascha K.A Grzimek

  • Two Antigenic Peptides from Genes m123 and m164 of Murine Cytomegalovirus Quantitatively Dominate CD8 T-Cell Memory in the H-2d Haplotype

    Rafaela Holtappels;Doris Thomas;Jürgen Podlech;Matthias J. Reddehase

  • Preemptive CD8 T-Cell Immunotherapy of Acute Cytomegalovirus Infection Prevents Lethal Disease, Limits the Burden of Latent Viral Genomes, and Reduces the Risk of Virus Recurrence

    Hans-Peter Steffens;Sabine Kurz;Rafaela Holtappels;Matthias J. Reddehase

  • A nonstructural viral protein expressed by a recombinant vaccinia virus protects against lethal cytomegalovirus infection.

    S Jonjić;M del Val;G M Keil;M J Reddehase

  • Cellular and molecular basis of the protective immune response to cytomegalovirus infection.

    U. H. Koszinowski;M. Del Val;M. J. Reddehase

  • Adoptive immunotherapy of murine cytomegalovirus adrenalitis in the immunocompromised host: CD4-helper-independent antiviral function of CD8-positive memory T lymphocytes derived from latently infected donors.

    M J Reddehase;S Jonjić;F Weiland;W Mutter

Frequent Co-Authors

Ulrich H. Koszinowski
Ulrich H. Koszinowski Ludwig-Maximilians-Universität München
Stipan Jonjić
Stipan Jonjić University of Rijeka
Günther M. Keil
Günther M. Keil Friedrich-Loeffler-Institut
Armin Saalmüller
Armin Saalmüller University of Veterinary Medicine Vienna
Hans-Jörg Bühring
Hans-Jörg Bühring University of Tübingen
Dennis Strand
Dennis Strand Johannes Gutenberg University of Mainz
Martin Messerle
Martin Messerle Hannover Medical School
Christopher H. Contag
Christopher H. Contag Michigan State University
Wolfgang Uckert
Wolfgang Uckert Max Delbrück Center for Molecular Medicine
Peter Ghazal
Peter Ghazal Cardiff University

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