World's Best Scientists 2026 revealed!
Edward S. Mocarski

Edward S. Mocarski

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Microbiology
USA
2025

D-Index & Metrics

Microbiology

D-Index
108
Citations
36087
World Ranking
268
National Ranking
123

Medicine

D-Index
108
Citations
36120
World Ranking
6070
National Ranking
3250

Research.com Recognitions

  • 2025 - Research.com Microbiology in United States Leader Award

Overview

Edward S. Mocarski is affiliated with Emory University in the United States. Their research primarily focuses on the fields of Medicine, Biochemistry, Genetics and Molecular Biology, and Immunology and Microbiology. Within these broader areas, their work is further specialized into subfields such as Molecular Biology, Immunology, Epidemiology, Infectious Diseases, and Parasitology.

The scientist's research topics include:

  • Cytomegalovirus and herpesvirus research
  • Interferon and immune responses
  • Inflammasome and immune disorders
  • Herpesvirus infections and treatments
  • Cell death mechanisms and regulation
  • Toxoplasma gondii research studies
  • Immune response and inflammation

Mocarski has published recent papers in various scientific journals, demonstrating a continued engagement with key issues in virology and immunology. Noteworthy publications include:

  • "Vaccinia virus E3 prevents sensing of Z-RNA to block ZBP1-dependent necroptosis," 2021, Cell Host & Microbe
  • "Squalene emulsion-based vaccine adjuvants stimulate CD8 T cell, but not antibody responses, through a RIPK3-dependent pathway," 2020, eLife
  • "Viral Z-RNA triggers ZBP1-dependent cell death," 2021, Current Opinion in Virology
  • "Characterisation of genetic regulatory effects for osteoporosis risk variants in human osteoclasts," 2020, Genome Biology
  • "KSHV (HHV8) vaccine: promises and potential pitfalls for a new anti-cancer vaccine," 2022, npj Vaccines

The scientist frequently publishes in established venues, including:

  • Viruses
  • Proceedings of the National Academy of Sciences
  • PLoS Pathogens
  • Nature
  • Cell Host & Microbe

Co-authorship is evident with a number of researchers with whom Mocarski has collaborated over multiple publications. Frequent coauthors include Heather Koehler, Pratyusha Mandal, Daniel Kalman, Hongyan Guo, and Siddharth Balachandran.

In addition to journal articles, Mocarski has contributed to the academic literature through book publications. Notably, they authored a book titled Alternate Programmed Cell Death Signaling in Antiviral Host Defense, published by Springer Science+Business Media in 2023.

Best Publications

  • Direct Recognition of Cytomegalovirus by Activating and Inhibitory NK Cell Receptors

    Hisashi Arase;Edward S. Mocarski;Ann E. Campbell;Ann B. Hill

  • RIP3 mediates the embryonic lethality of caspase-8-deficient mice

    William J. Kaiser;Jason W. Upton;Alyssa B. Long;Devon Livingston-Rosanoff

  • Toll-like Receptor 3-mediated Necrosis via TRIF, RIP3, and MLKL

    William J. Kaiser;Haripriya Sridharan;Chunzi Huang;Pratyusha Mandal

  • Human Herpesviruses: Biology, Therapy, and Immunoprophylaxis

    Ann Arvin;Gabriella Campadelli-Fiume;Edward Mocarski;Patrick S. Moore

  • Human cytomegalovirus clinical isolates carry at least 19 genes not found in laboratory strains.

    Tai-An Cha;E. Tom;G. W. Kemble;G. M. Duke

  • DAI/ZBP1/DLM-1 Complexes with RIP3 to Mediate Virus-Induced Programmed Necrosis that Is Targeted by Murine Cytomegalovirus vIRA

    Jason W. Upton;William J. Kaiser;Edward S. Mocarski

  • Cytomegalovirus remains latent in a common precursor of dendritic and myeloid cells

    Gabriele Hahn;Rita Jores;Edward S. Mocarski

  • Virus Inhibition of RIP3-Dependent Necrosis

    Jason W. Upton;William J. Kaiser;Edward S. Mocarski

  • RIP3 induces apoptosis independent of pronecrotic kinase activity.

    Pratyusha Mandal;Scott B. Berger;Sirika Pillay;Kenta Moriwaki

  • A cytomegalovirus-encoded inhibitor of apoptosis that suppresses caspase-8 activation.

    Anna Skaletskaya;Laura M. Bartle;Thomas Chittenden;A. Louise McCormick

  • A cytomegalovirus-encoded mitochondria-localized inhibitor of apoptosis structurally unrelated to Bcl-2

    Victor S. Goldmacher;Laura M. Bartle;Anna Skaletskaya;Cheryl A. Dionne

  • Cytomegalovirus encodes a potent alpha chemokine.

    Mark E. T. Penfold;Daniel J. Dairaghi;Gregory M. Duke;Noah Saederup

  • Human cytomegalovirus latent infection of granulocyte-macrophage progenitors.

    Kazuhiro Kondo;Hideto Kaneshima;Edward S. Mocarski

  • NF-kappa B activation of the cytomegalovirus enhancer is mediated by a viral transactivator and by T cell stimulation.

    L. C. Sambucetti;J. M. Cherrington;G. W. G. Wilkinson;E. S. Mocarski

  • Cutting Edge: RIP1 Kinase Activity Is Dispensable for Normal Development but Is a Key Regulator of Inflammation in SHARPIN-Deficient Mice

    Scott B. Berger;Viera Kasparcova;Sandy Hoffman;Barb Swift

  • Human cytomegalovirus ie1 transactivates the alpha promoter-enhancer via an 18-base-pair repeat element.

    J M Cherrington;E S Mocarski

  • Activation of Innate Immunity Is Required for Efficient Nuclear Reprogramming

    Jieun Lee;Nazish Sayed;Arwen Hunter;Kin Fai Au

  • RIPK3 Activates Parallel Pathways of MLKL-Driven Necroptosis and FADD-Mediated Apoptosis to Protect against Influenza A Virus

    Shoko Nogusa;Roshan J. Thapa;Christopher P. Dillon;Swantje Liedmann

  • Human cytomegalovirus latent gene expression in granulocyte-macrophage progenitors in culture and in seropositive individuals.

    Kazuhiro Kondo;Jiake Xu;Edward S. Mocarski

  • Immunomodulation by cytomegaloviruses: manipulative strategies beyond evasion

    Edward S Mocarski

  • Human Herpesviruses: Basic virology and viral gene effects on host cell functions: alphaherpesviruses

    Gabriella Campadelli-Fiume;Bernard Roizman

Frequent Co-Authors

Bernard Roizman
Bernard Roizman University of Chicago
Patrick S. Moore
Patrick S. Moore University of Pittsburgh
Koichi Yamanishi
Koichi Yamanishi Osaka University
John P. Cooke
John P. Cooke Houston Methodist
Peter J. Gough
Peter J. Gough Inzen Therapeutics
Barry Slobedman
Barry Slobedman University of Sydney
John Bertin
John Bertin GlaxoSmithKline (United Kingdom)
William F. Fearon
William F. Fearon Stanford University
Elizabeth D. Mellins
Elizabeth D. Mellins Stanford University
Lewis L. Lanier
Lewis L. Lanier University of California, San Francisco

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