Martine J. Smit

Overview

Best Publications

• Biogenesis and function of extracellular vesicles in cancer.

  Maarten P Bebelman;Martine J Smit;D Michiel Pegtel;S Rubina Baglio

  719
  Citations

• Molecular pharmacological aspects of histamine receptors.

  R Leurs;M.J Smit;H Timmerman

  462
  Citations

• Quantifying exosome secretion from single cells reveals a modulatory role for GPCR signaling

  Frederik Johannes Verweij;Frederik Johannes Verweij;Frederik Johannes Verweij;Maarten P. Bebelman;Maarten P. Bebelman;Connie R. Jimenez;Juan J. Garcia-Vallejo

  367
  Citations

• Identification of Rat H3 Receptor Isoforms with Different Brain Expression and Signaling Properties

  Guillaume Drutel;Nina Peitsaro;Kaj Karlstedt;Kerstin Wieland

  357
  Citations

• Histamine H(1)-receptor activation of nuclear factor-kappa B: roles for G beta gamma- and G alpha(q/11)-subunits in constitutive and agonist-mediated signaling.

  Remko A. Bakker;Stefan B. J. Schoonus;Martine J. Smit;Henk Timmerman

  350
  Citations

• Consensus on the role of human cytomegalovirus in glioblastoma

  Kristine Dziurzynski;Susan M. Chang;Amy B. Heimberger;Robert F. Kalejta

  336
  Citations

• Constitutive Signaling of the Human Cytomegalovirus-encoded Chemokine Receptor US28 *

  Paola Casarosa;Remko A. Bakker;Dennis Verzijl;Marjon Navis

  328
  Citations

• Human cytomegalovirus-encoded chemokine receptor US28 promotes tumorigenesis

  David Maussang;Dennis Verzijl;Marijke van Walsum;Rob Leurs

  300
  Citations

• Pharmacological modulation of chemokine receptor function

  DJ Scholten;M Canals;D Maussang;L Roumen

  297
  Citations

• Inverse agonism of histamine H2 antagonist accounts for upregulation of spontaneously active histamine H2 receptors

  M J Smit;R Leurs;A E Alewijnse;J Blauw

  268
  Citations

• CXCR4 nanobodies (VHH-based single variable domains) potently inhibit chemotaxis and HIV-1 replication and mobilize stem cells

  Sven Jähnichen;Christophe Blanchetot;David Maussang;Maria Gonzalez-Pajuelo

  266
  Citations

• The effect of mutations in the DRY motif on the constitutive activity and structural instability of the histamine H(2) receptor

  Astrid E. Alewijnse;Henk Timmerman;Edwin H. Jacobs;Martine J. Smit

  265
  Citations

• Increased Hepatobiliary and Fecal Cholesterol Excretion Upon Activation of the Liver X Receptor Is Independent of ABCA1

  Torsten Plōsch;Tineke Kok;Vincent W Bloks;Martin J Smit

  260
  Citations

• HCMV-Encoded Chemokine Receptor US28 Mediates Proliferative Signaling Through the IL-6–STAT3 Axis

  Erik Slinger;David Maussang;Andreas Schreiber;Marco Siderius

  259
  Citations

• CXCR3-mediated chemotaxis of human T cells is regulated by a Gi- and phospholipase C-dependent pathway and not via activation of MEK/p44/p42 MAPK nor Akt/PI-3 kinase.

  Martine J. Smit;Martine J. Smit;Pauline Verdijk;Pauline Verdijk;Elisabeth M. H. van der Raaij-Helmer;Elisabeth M. H. van der Raaij-Helmer;Marjon Navis;Marjon Navis

  237
  Citations

• Pharmacogenomic and Structural Analysis of Constitutive G Protein–Coupled Receptor Activity

  Martine J Smit;Henry F Vischer;Remko A Bakker;Aldo Jongejan

  230
  Citations

• Agonist-independent regulation of constitutively active G-protein-coupled receptors

  Rob Leurs;Martine J Smit;Astrid E Alewijnse;Henk Timmerman

  198
  Citations

• The human cytomegalovirus-encoded chemokine receptor US28 promotes angiogenesis and tumor formation via cyclooxygenase-2.

  David Maussang;Ellen Langemeijer;Carlos P. Fitzsimons;Marijke Stigter-van Walsum

  190
  Citations

• Adenylyl cyclase 6 is selectively regulated by protein kinase A phosphorylation in a region involved in Galphas stimulation

  Yibang Chen;Anya Harry;Jingrong Li;Martine J. Smit

  186
  Citations

• Llama-derived single variable domains (nanobodies) directed against chemokine receptor CXCR7 reduce head and neck cancer cell growth in vivo.

  David Maussang;Azra Mujić-Delić;Francis J. Descamps;Catelijne Stortelers

  185
  Citations