Martine J. Smit mainly focuses on Chemokine receptor, Cell biology, Receptor, Signal transduction and Molecular biology. Her study looks at the intersection of Chemokine receptor and topics like Cancer research with Immunology. In Cell biology, she works on issues like Biochemistry, which are connected to Stimulation.
Her Receptor research is multidisciplinary, relying on both Neuroscience and Pharmacology, Histamine. The Signal transduction study which covers Transcription factor that intersects with Alpha. Her Molecular biology study combines topics from a wide range of disciplines, such as Wnt signaling pathway, Intestinal mucosa, Transgene and COS cells, Transfection.
Chemokine receptor, Receptor, G protein-coupled receptor, Cell biology and Chemokine are her primary areas of study. Her work in Chemokine receptor tackles topics such as Cancer research which are related to areas like Cancer. Her studies deal with areas such as Molecular biology, Stereochemistry and Pharmacology as well as Receptor.
As a member of one scientific family, Martine J. Smit mostly works in the field of Molecular biology, focusing on Histamine and, on occasion, Histamine H3 receptor. The concepts of her G protein-coupled receptor study are interwoven with issues in Inverse agonist, Computational biology, G protein and Virology. Her Cell biology research includes themes of Carcinogenesis and Chemotaxis.
Her primary scientific interests are in Chemokine receptor, G protein-coupled receptor, Receptor, Cell biology and Signal transduction. Her Chemokine receptor study improves the overall literature in Chemokine. When carried out as part of a general Chemokine research project, her work on Chemokine binding is frequently linked to work in Neurosphere, therefore connecting diverse disciplines of study.
She interconnects Viral Receptor, Virus, Viral replication, Computational biology and Drug discovery in the investigation of issues within G protein-coupled receptor. Her CXC chemokine receptors study, which is part of a larger body of work in Receptor, is frequently linked to Severe morbidity, bridging the gap between disciplines. Her work on Endosome is typically connected to Exosome as part of general Cell biology study, connecting several disciplines of science.
The scientist’s investigation covers issues in G protein-coupled receptor, Cell biology, Receptor, Chemokine receptor and Signal transduction. Her study on GPCR activity is often connected to Membrane protein as part of broader study in G protein-coupled receptor. Her research integrates issues of Epitope and CXCR4 in her study of Cell biology.
Her work in the fields of Histamine H3 receptor overlaps with other areas such as Characterization. Her Signal transduction study combines topics in areas such as HEK 293 cells, Cell culture and Chemokine. Her Cancer research research incorporates elements of Pharmaceutical sciences, Regulation of gene expression, Human cytomegalovirus and Chemokine binding.
This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.
Molecular pharmacological aspects of histamine receptors.
R Leurs;M.J Smit;H Timmerman.
Pharmacology & Therapeutics (1995)
Identification of Rat H3 Receptor Isoforms with Different Brain Expression and Signaling Properties
Guillaume Drutel;Nina Peitsaro;Kaj Karlstedt;Kerstin Wieland.
Molecular Pharmacology (2001)
Histamine H(1)-receptor activation of nuclear factor-kappa B: roles for G beta gamma- and G alpha(q/11)-subunits in constitutive and agonist-mediated signaling.
Remko A. Bakker;Stefan B. J. Schoonus;Martine J. Smit;Henk Timmerman.
Molecular Pharmacology (2001)
Constitutive signaling of the human cytomegalovirus-encoded chemokine receptor US28.
Paola Casarosa;Remko A. Bakker;Dennis Verzijl;Marjon Navis.
Journal of Biological Chemistry (2001)
Consensus on the role of human cytomegalovirus in glioblastoma
Kristine Dziurzynski;Susan M. Chang;Amy B. Heimberger;Robert F. Kalejta.
Neuro-oncology (2012)
Human cytomegalovirus-encoded chemokine receptor US28 promotes tumorigenesis
David Maussang;Dennis Verzijl;Marijke van Walsum;Rob Leurs.
Proceedings of the National Academy of Sciences of the United States of America (2006)
Inverse agonism of histamine H2 antagonist accounts for upregulation of spontaneously active histamine H2 receptors
M J Smit;R Leurs;A E Alewijnse;J Blauw.
Proceedings of the National Academy of Sciences of the United States of America (1996)
The effect of mutations in the DRY motif on the constitutive activity and structural instability of the histamine H(2) receptor
Astrid E. Alewijnse;Henk Timmerman;Edwin H. Jacobs;Martine J. Smit.
Molecular Pharmacology (2000)
CXCR4 nanobodies (VHH-based single variable domains) potently inhibit chemotaxis and HIV-1 replication and mobilize stem cells
.
Proceedings of the National Academy of Sciences of the United States of America (2010)
Pharmacological modulation of chemokine receptor function
DJ Scholten;M Canals;D Maussang;L Roumen.
British Journal of Pharmacology (2012)
If you think any of the details on this page are incorrect, let us know.
We appreciate your kind effort to assist us to improve this page, it would be helpful providing us with as much detail as possible in the text box below:
Vrije Universiteit Amsterdam
Leiden University Medical Center
Maastricht University Medical Centre
Maastricht University
Icahn School of Medicine at Mount Sinai
University of Nottingham
Icahn School of Medicine at Mount Sinai
Institut Curie
Max Delbrück Center for Molecular Medicine
Vrije Universiteit Amsterdam
Boston University
Nanjing University of Finance and Economics
Lawrence Berkeley National Laboratory
Spanish National Research Council
Nagoya Institute of Technology
Indian Institute of Technology Kharagpur
Nihon University
Johns Hopkins University School of Medicine
Université Paris Cité
National Oceanography Centre
Swedish Meteorological and Hydrological Institute
University of Connecticut
University of Illinois at Urbana-Champaign
Stanford University
MIT
Princeton University