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Molecular Biology

D-Index
80
Citations
23244
World Ranking
999
National Ranking
528

Overview

Gabriele Varani is affiliated with the University of Washington in the United States. Their research focuses primarily on biochemistry, genetics, and molecular biology, with specific expertise in molecular biology, cancer research, public health, environmental and occupational health, biomedical engineering, and insect science.

The research topics Varani has extensively covered include:

  • RNA Research and Splicing
  • RNA and protein synthesis mechanisms
  • RNA modifications and cancer
  • Mosquito-borne diseases and control
  • MicroRNA in disease regulation
  • Cancer-related molecular mechanisms research
  • Insect symbiosis and bacterial influences

Varani has contributed to multiple peer-reviewed journals and conferences. Some of the frequent publication venues are:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Journal of Molecular Biology
  • RNA
  • Talanta
  • Journal of Back and Musculoskeletal Rehabilitation

Selected recent papers authored or co-authored by Varani include:

  • "The Long Noncoding RNA CCAT2 Induces Chromosomal Instability Through BOP1-AURKB Signaling," 2020, Gastroenterology
  • "Primordial emergence of a nucleic acid-binding protein via phase separation and statistical ornithine-to-arginine conversion," 2020, Proceedings of the National Academy of Sciences
  • "High blood flow shear stress values are associated with circulating tumor cells cluster disaggregation in a multi-channel microfluidic device," 2021, PLoS ONE
  • "Investigating the Role of Polydopamine to Modulate Stem Cell Adhesion and Proliferation on Gellan Gum-Based Hydrogels," 2020, ACS Applied Bio Materials
  • "An evolutionarily conserved RNA structure in the functional core of the lincRNA Cyrano," 2020, RNA

Frequent co-authors with whom Varani has collaborated include:

  • Matthew D. Shortridge
  • Daniele Zappi
  • George A. Călin
  • Maria Teresa Giardi
  • Gregory L. Olsen

Best Publications

  • Design of a Novel Globular Protein Fold with Atomic-Level Accuracy

    Brian A Kuhlman;Gautam Dantas;Gregory C. Ireton;Gabriele Varani

  • RNA-binding proteins: modular design for efficient function.

    Bradley M. Lunde;Claire Moore;Gabriele Varani

  • The G·U wobble base pair: A fundamental building block of RNA structure crucial to RNA function in diverse biological systems

    Gabriele Varani;William H McClain

  • Solution structure of an unusually stable RNA hairpin, 5'GGAC(UUCG)GUCC.

    Chaejoon Cheong;Gabriele Varani;Ignacio Tinoco

  • The Structure of the Human Immunodeficiency Virus Type-1 TAR RNA Reveals Principles of RNA Recognition by Tat Protein

    Fareed Aboul-ela;Jonathan Karn;Gabriele Varani

  • NMR investigation of RNA structure

    Gabriele Varani;Fareed Aboul-ela;Frédéric H.-T. Allain

  • RNA recognition by a Staufen double‐stranded RNA‐binding domain

    Andres Ramos;Stefan Grünert;Jan Adams;David R. Micklem

  • The structure and function of small nucleolar ribonucleoproteins

    Steve L. Reichow;Tomoko Hamma;Adrian R. Ferré-D'Amaré;Gabriele Varani

  • Exceptionally Stable Nucleic Acid Hairpins

    G Varani

  • RNA recognition by RNP proteins during RNA processing.

    Gabriele Varani;Kiyoshi Nagai

  • Structure of an unusually stable RNA hairpin.

    Gabriele Varani;Chaejoon Cheong;Ignacio Tinoco

  • Current topics in RNA-protein recognition: control of specificity and biological function through induced fit and conformational capture.

    Nicolas Leulliot;Gabriele Varani

  • Targeting RNA with small-molecule drugs: therapeutic promise and chemical challenges.

    José Gallego;Gabriele Varani

  • Structure of the P1 helix from group I self-splicing introns.

    Frédéric H.-T. Allain;Gabriele Varani

  • An inhibitor of the Tat/TAR RNA interaction that effectively suppresses HIV-1 replication

    François Hamy;Eduard R. Felder;Gerhard Heizmann;Janis Lazdins

  • RNA structure and NMR spectroscopy.

    Gabriele Varani;Ignacio Tinoco

  • Structure of HIV-1 TAR RNA in the Absence of Ligands Reveals a Novel Conformation of the Trinucleotide Bulge

    Fareed Aboul-ela;Jonathan Karn;Gabriele Varani

  • Specificity of ribonucleoprotein interaction determined by RNA folding during complex formation

    Frédéric H.-T. Allain;Charles C. Gubser;Peter W. A. Howe;Kiyoshi Nagai

  • The conformation of loop E of eukaryotic 5S ribosomal RNA.

    Brian Wimberly;Gabriele Varani;Ignacio Tinoco

  • Structure of tau exon 10 splicing regulatory element RNA and destabilization by mutations of frontotemporal dementia and parkinsonism linked to chromosome 17

    Luca Varani;Masato Hasegawa;Maria Grazia Spillantini;Michael J. Smith

Frequent Co-Authors

Gary P. Drobny
Gary P. Drobny University of Washington
Ignacio Tinoco
Ignacio Tinoco University of California, Berkeley
David Baker
David Baker University of Washington
Jonathan Karn
Jonathan Karn Case Western Reserve University
Claire Moore
Claire Moore Tufts University
Wen Yang
Wen Yang Beijing Institute of Technology
John A. Robinson
John A. Robinson University of Zurich
Peter J. Myler
Peter J. Myler Seattle Children's Hospital
Gautam Dantas
Gautam Dantas Washington University in St. Louis

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