D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Molecular Biology D-index 74 Citations 20,286 242 World Ranking 754 National Ranking 415

Overview

What is she best known for?

The fields of study she is best known for:

  • DNA
  • Gene
  • RNA

The scientist’s investigation covers issues in RNA, RNA-binding protein, Stereochemistry, Nucleic acid structure and Biochemistry. Her studies deal with areas such as Computational biology, Function, Cell biology and Binding site as well as RNA. She has researched Stereochemistry in several fields, including RNA Conformation, Base pair, Wobble base pair and Nucleic acid secondary structure.

Her Nucleic acid structure study combines topics from a wide range of disciplines, such as Fluorine-19 NMR, Nuclear magnetic resonance spectroscopy, Biophysics, Internal ribosome entry site and Nuclear magnetic resonance spectroscopy of nucleic acids. Her work focuses on many connections between Fluorine-19 NMR and other disciplines, such as Scalar coupling, that overlap with her field of interest in Crystallography. Her study on Transcription and PAR-CLIP is often connected to Modular design and Modular structure as part of broader study in Biochemistry.

Her most cited work include:

  • Design of a Novel Globular Protein Fold with Atomic-Level Accuracy (1281 citations)
  • RNA-binding proteins: modular design for efficient function. (842 citations)
  • Solution structure of an unusually stable RNA hairpin, 5'GGAC(UUCG)GUCC. (335 citations)

What are the main themes of her work throughout her whole career to date?

Gabriele Varani mainly focuses on RNA, Biochemistry, Crystallography, Cell biology and RNA-binding protein. She is interested in Nucleic acid structure, which is a field of RNA. Her research investigates the connection between Biochemistry and topics such as Stereochemistry that intersect with problems in Wobble base pair and Nucleic acid.

While the research belongs to areas of Crystallography, Gabriele Varani spends her time largely on the problem of Biological system, intersecting her research to questions surrounding Molecule. Her Cell biology research includes themes of Genetics, Molecular biology, Messenger RNA, Regulation of gene expression and RNA polymerase II. Her work deals with themes such as Ribonucleoprotein, Polyadenylation and RNA silencing, which intersect with RNA-binding protein.

She most often published in these fields:

  • RNA (55.86%)
  • Biochemistry (22.27%)
  • Crystallography (15.23%)

What were the highlights of her more recent work (between 2013-2021)?

  • RNA (55.86%)
  • Biochemistry (22.27%)
  • Cell biology (14.84%)

In recent papers she was focusing on the following fields of study:

Her primary scientific interests are in RNA, Biochemistry, Cell biology, Crystallography and Computational biology. Her study in RNA focuses on Nucleic acid structure in particular. Her Protein structure, Phosphatase and Thioredoxin study in the realm of Biochemistry interacts with subjects such as Mycobacterium thermoresistibile and Neurotoxicity.

Her study in Cell biology is interdisciplinary in nature, drawing from both Genetics, Protein subunit, microRNA, Regulation of gene expression and RNA polymerase II. Her Solution structure study, which is part of a larger body of work in Crystallography, is frequently linked to Replica, bridging the gap between disciplines. Her Computational biology research incorporates themes from RNA-binding protein, Nucleotide, Small Molecule Libraries and Ribozyme.

Between 2013 and 2021, her most popular works were:

  • Comprehensive computational design of ordered peptide macrocycles. (64 citations)
  • α-Sheet secondary structure in amyloid β-peptide drives aggregation and toxicity in Alzheimer’s disease (48 citations)
  • Structure based approaches for targeting non-coding RNAs with small molecules. (46 citations)

In her most recent research, the most cited papers focused on:

  • DNA
  • Gene
  • Enzyme

Her primary areas of study are RNA, Cell biology, Binding site, Biochemistry and microRNA. Her RNA study combines topics in areas such as Crystallography, Transactivation, Molecular biology, Small molecule and Computational biology. Her Crystallography research focuses on subjects like Nucleic acid structure, which are linked to Biophysics.

Her Cell biology research integrates issues from RNA polymerase II, Genetics and Protein subunit. Her Binding site research is multidisciplinary, incorporating perspectives in Polyadenylation, Transcription, Regulation of gene expression and Protein domain. Her work on RNA-binding protein, Cytotoxicity and Amyloid beta as part of general Biochemistry study is frequently linked to Monomer, bridging the gap between disciplines.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Design of a Novel Globular Protein Fold with Atomic-Level Accuracy

Brian A Kuhlman;Gautam Dantas;Gregory C. Ireton;Gabriele Varani.
Science (2003)

1896 Citations

RNA-binding proteins: modular design for efficient function.

Bradley M. Lunde;Claire Moore;Gabriele Varani.
Nature Reviews Molecular Cell Biology (2007)

1490 Citations

Solution structure of an unusually stable RNA hairpin, 5'GGAC(UUCG)GUCC.

Chaejoon Cheong;Gabriele Varani;Ignacio Tinoco.
Nature (1990)

569 Citations

The G·U wobble base pair: A fundamental building block of RNA structure crucial to RNA function in diverse biological systems

Gabriele Varani;William H McClain.
EMBO Reports (2000)

540 Citations

The Structure of the Human Immunodeficiency Virus Type-1 TAR RNA Reveals Principles of RNA Recognition by Tat Protein

Fareed Aboul-ela;Jonathan Karn;Gabriele Varani.
Journal of Molecular Biology (1995)

510 Citations

NMR investigation of RNA structure

Gabriele Varani;Fareed Aboul-ela;Frédéric H.-T. Allain.
Progress in Nuclear Magnetic Resonance Spectroscopy (1996)

491 Citations

RNA recognition by a Staufen double‐stranded RNA‐binding domain

Andres Ramos;Stefan Grünert;Jan Adams;David R. Micklem.
The EMBO Journal (2000)

447 Citations

The structure and function of small nucleolar ribonucleoproteins

Steve L. Reichow;Tomoko Hamma;Adrian R. Ferré-D'Amaré;Gabriele Varani.
Nucleic Acids Research (2007)

420 Citations

Exceptionally Stable Nucleic Acid Hairpins

G Varani.
Annual Review of Biophysics and Biomolecular Structure (1995)

419 Citations

RNA recognition by RNP proteins during RNA processing.

Gabriele Varani;Kiyoshi Nagai.
Annual Review of Biophysics and Biomolecular Structure (1998)

419 Citations

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