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Biology and Biochemistry

D-Index
81
Citations
29849
World Ranking
3816
National Ranking
285

Overview

Michael Sattler is affiliated with the Technical University of Munich in Germany. Their research primarily focuses on the field of Biochemistry, Genetics and Molecular Biology, with a significant emphasis on Molecular Biology as a subfield. Their work also spans areas such as Materials Chemistry, Epidemiology, Immunology, and Infectious Diseases.

The scientist's research interests include several major topics related to RNA and protein biology. These topics are:

  • RNA Research and Splicing
  • RNA modifications and cancer
  • RNA and protein synthesis mechanisms
  • Protein Structure and Dynamics
  • Enzyme Structure and Function
  • Heat shock proteins research
  • Computational Drug Discovery Methods

Their publication record shows frequent contributions to several scientific venues. The most common platforms for their research dissemination are:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Nature Communications
  • Zenodo (CERN European Organization for Nuclear Research)
  • Nucleic Acids Research
  • Journal of Molecular Biology

Michael Sattler has collaborated extensively with other researchers. Frequent coauthors include:

  • Grzegorz M. Popowicz
  • Hyun-Seo Kang
  • Alisha N Jones
  • Arie Geerlof
  • André Mourão

Selected recent publications illustrate the scope and focus of Sattler's work:

  • Active coacervate droplets as a model for membraneless organelles and protocells, 2020, Nature Communications
  • Phase separation of FSP1 promotes ferroptosis, 2023, Nature
  • Noncanonical inhibition of caspase-3 by a nuclear microRNA confers endothelial protection by autophagy in atherosclerosis, 2020, Science Translational Medicine
  • Reliability and accuracy of single-molecule FRET studies for characterization of structural dynamics and distances in proteins, 2023, Nature Methods
  • Conformational dynamics modulate the catalytic activity of the molecular chaperone Hsp90, 2020, Nature Communications

Best Publications

  • FSP1 is a glutathione-independent ferroptosis suppressor

    Sebastian Doll;Florencio Porto Freitas;Ron Shah;Maceler Aldrovandi

  • Heteronuclear multidimensional NMR experiments for the structure determination of proteins in solution employing pulsed field gradients

    Michael Sattler;Jürgen Schleucher;Christian Griesinger

  • X-ray and NMR structure of human Bcl-xL, an inhibitor of programmed cell death.

    Steven W. Muchmore;Michael Sattler;Heng Liang;Robert P. Meadows

  • Structure of Bcl-xL-Bak peptide complex: recognition between regulators of apoptosis.

    Michael Sattler;Heng Liang;David Nettesheim;Robert P. Meadows

  • A general enhancement scheme in heteronuclear multidimensional NMR employing pulsed field gradients.

    J. Schleucher;M. Schwendinger;M. Sattler;P. Schmidt

  • Structure and nucleic-acid binding of the Drosophila Argonaute 2 PAZ domain

    Andreas Lingel;Bernd Simon;Elisa Izaurralde;Michael Sattler

  • Structure and ligand recognition of the phosphotyrosine binding domain of Shc.

    Ming-Ming Zhou;Kodimangalam S. Ravichandran;Edward T. Olejniczak;Andrew M. Petros

  • Nucleic acid 3′-end recognition by the Argonaute2 PAZ domain

    Andreas Lingel;Bernd Simon;Elisa Izaurralde;Michael Sattler

  • SMN tudor domain structure and its interaction with the Sm proteins.

    Philipp Selenko;Remco Sprangers;Gunter Stier;Dirk Bühler

  • Endothelin 1 transcription is controlled by nuclear factor-kappaB in AGE-stimulated cultured endothelial cells.

    P. Quehenberger;A. Bierhaus;P. Fasching;C. Muellner

  • Coherence Selection by Gradients without Signal Attenuation: Application to the Three‐Dimensional HNCO Experiment

    Jürgen Schleucher;Michael Sattler;Christian Griesinger

  • Structural Basis for Recognition of the Intron Branch Site RNA by Splicing Factor 1

    Zhihong Liu;Ingrid Luyten;Matthew J. Bottomley;Ana C. Messias

  • NES consensus redefined by structures of PKI-type and Rev-type nuclear export signals bound to CRM1

    Thomas Güttler;Tobias Madl;Piotr Neumann;Danilo Deichsel

  • The SAND domain structure defines a novel DNA-binding fold in transcriptional regulation.

    Matthew J. Bottomley;Michael W. Collard;Jodi I. Huggenvik;Zhihong Liu

  • Structural basis for the molecular recognition between human splicing factors U2AF65 and SF1/mBBP

    Philipp Selenko;Goran Gregorovic;Remco Sprangers;Gunter Stier

  • Multi-domain conformational selection underlies pre-mRNA splicing regulation by U2AF

    Cameron D. Mackereth;Tobias Madl;Sophie Bonnal;Bernd Simon

  • High-resolution X-ray and NMR Structures of the SMN Tudor Domain: Conformational Variation in the Binding Site for Symmetrically Dimethylated Arginine Residues

    Remco Sprangers;Matthew R Groves;Irmgard Sinning;Michael Sattler

  • Active coacervate droplets as a model for membraneless organelles and protocells.

    Carsten Donau;Fabian Späth;Marilyne Sosson;Brigitte A. K. Kriebisch

  • Structural basis for dimethylarginine recognition by the Tudor domains of human SMN and SPF30 proteins

    Konstantinos Tripsianes;Tobias Madl;Martin Machyna;Dimitrios Fessas

  • NMR approaches for structural analysis of multidomain proteins and complexes in solution.

    Christoph Göbl;Tobias Madl;Tobias Madl;Bernd Simon;Michael Sattler

Frequent Co-Authors

Ralf Erdmann
Ralf Erdmann Ruhr University Bochum
Johannes Buchner
Johannes Buchner Technical University of Munich
Juan Valcárcel
Juan Valcárcel Institució Catalana de Recerca i Estudis Avançats
Matthias Wilmanns
Matthias Wilmanns Universität Hamburg
Carlo Camilloni
Carlo Camilloni University of Milan
Steffen J. Glaser
Steffen J. Glaser Technical University of Munich
Michael Nilges
Michael Nilges Université Paris Cité
Christian Griesinger
Christian Griesinger Max Planck Society
Don C. Lamb
Don C. Lamb Ludwig-Maximilians-Universität München
Elisa Izaurralde
Elisa Izaurralde Max Planck Institute for Developmental Biology

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