D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Biology and Biochemistry D-index 56 Citations 12,006 271 World Ranking 9856 National Ranking 725

Overview

What is he best known for?

The fields of study Takeshi Ikeuchi is best known for:

  • Gene
  • Alzheimer's disease
  • Enzyme

The study of Presenilin, Tau protein and Amyloid precursor protein are components of his Alzheimer's disease research. His study connects Internal medicine and Amyloid precursor protein. His Presenilin research extends to Internal medicine, which is thematically connected. Disease is closely attributed to Dementia in his study. His Dementia study frequently links to other fields, such as Disease. Takeshi Ikeuchi performs multidisciplinary study in the fields of Gene and Molecular biology via his papers. Takeshi Ikeuchi carries out multidisciplinary research, doing studies in Molecular biology and Gene. Takeshi Ikeuchi regularly ties together related areas like Gene expression in his Genetics studies. His Pathology study frequently links to other fields, such as Amyloid (mycology).

His most cited work include:

  • Human and mouse single-nucleus transcriptomics reveal TREM2-dependent and TREM2-independent cellular responses in Alzheimer’s disease (478 citations)
  • Expanded polyglutamine stretches interact with TAFII130, interfering with CREB-dependent transcription (383 citations)
  • A neurological disease caused by an expanded CAG trinucleotide repeat in the TATA-binding protein gene: a new polyglutamine disease? [In Process Citation] (365 citations)

What are the main themes of his work throughout his whole career to date

Takeshi Ikeuchi has begun a study into Gene, looking into Mutation and Allele. He connects Mutation with Gene in his research. Takeshi Ikeuchi regularly ties together related areas like Neurodegeneration in his Disease studies. Neurodegeneration and Disease are commonly linked in his work. Takeshi Ikeuchi regularly ties together related areas like Atrophy in his Pathology studies. He frequently studies issues relating to Pathology and Atrophy. Takeshi Ikeuchi combines Genetics and Allele in his research. He incorporates Internal medicine and Psychiatry in his research. While working on this project, he studies both Psychiatry and Internal medicine.

Takeshi Ikeuchi most often published in these fields:

  • Disease (79.72%)
  • Pathology (55.94%)
  • Gene (51.05%)

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Unstable expansion of CAG repeat in hereditary dentatorubral–pallidoluysian atrophy (DRPLA)

R. Koide;T. Ikeuchi;O. Onodera;H. Tanaka.
Nature Genetics (1994)

1362 Citations

Identification of the spinocerebellar ataxia type 2 gene using a direct identification of repeat expansion and cloning technique, DIRECT.

K Sanpei;H Takano;S Igarashi;T Sato.
Nature Genetics (1996)

864 Citations

Expanded polyglutamine stretches interact with TAFII130, interfering with CREB-dependent transcription.

Takayoshi Shimohata;Toshihiro Nakajima;Mitsunori Yamada;Chiharu Uchida.
Nature Genetics (2000)

485 Citations

TDP-43 mutation in familial amyotrophic lateral sclerosis

Akio Yokoseki;Atsushi Shiga;Chun-Feng Tan;Asako Tagawa.
Annals of Neurology (2008)

444 Citations

A Neurological Disease Caused By an Expanded CAG Trinucleotide Repeat in The TATA-Binding Protein Gene: A New Polyglutamine Disease?

Reiji Koide;Shigeichi Kobayashi;Takayoshi Shimohata;Takeshi Ikeuchi.
Human Molecular Genetics (1999)

440 Citations

Suppression of aggregate formation and apoptosis by transglutaminase inhibitors in cells expressing truncated DRPLA protein with an expanded polyglutamine stretch.

Shuichi Igarashi;Reiji Koide;Takayoshi Shimohata;Mitsunori Yamada.
Nature Genetics (1998)

405 Citations

Human and mouse single-nucleus transcriptomics reveal TREM2-dependent and TREM2-independent cellular responses in Alzheimer’s disease

Yingyue Zhou;Wilbur M. Song;Prabhakar S. Andhey;Amanda Swain.
Nature Medicine (2020)

388 Citations

Characterization of a Presenilin-mediated Amyloid Precursor Protein Carboxyl-terminal Fragment γ EVIDENCE FOR DISTINCT MECHANISMS INVOLVED IN γ-SECRETASE PROCESSING OF THE APP AND Notch1 TRANSMEMBRANE DOMAINS

Chunjiang Yu;Seong-Hun Kim;Takeshi Ikeuchi;Huaxi Xu.
Journal of Biological Chemistry (2001)

295 Citations

Close Associations between Prevalences of Dominantly Inherited Spinocerebellar Ataxias with CAG-Repeat Expansions and Frequencies of Large Normal CAG Alleles in Japanese and Caucasian Populations

H. Takano;G. Cancel;T. Ikeuchi;D. Lorenzetti.
American Journal of Human Genetics (1998)

281 Citations

The Notch ligands, Delta1 and Jagged2, are substrates for presenilin-dependent "gamma-secretase" cleavage.

Takeshi Ikeuchi;Sangram S. Sisodia.
Journal of Biological Chemistry (2003)

276 Citations

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