World's Best Scientists 2026 revealed!
Ryozo Kuwano

Ryozo Kuwano

D-Index & Metrics

Biology and Biochemistry

D-Index
57
Citations
10086
World Ranking
13988
National Ranking
986

Overview

Ryozo Kuwano is affiliated with Niigata University in Japan. Their research spans multiple disciplines within medicine and biochemistry, genetics, and molecular biology, with a significant focus on neurodegenerative conditions, cognitive impairment, and intellectual disabilities.

The scientist's work frequently appears in several publication venues, including:

  • Scientific Reports
  • Alzheimer s Research & Therapy
  • Human Molecular Genetics
  • International Journal of Geriatric Psychiatry
  • BMJ Neurology Open

Key recent papers by Ryozo Kuwano include:

  • Disruption of a RAC1-centred network is associated with Alzheimer's disease pathology and causes age-dependent neurodegeneration, 2020, Human Molecular Genetics
  • Prevalence of dementia in people with intellectual disabilities: Cross-sectional study, 2020, International Journal of Geriatric Psychiatry
  • Different AT(N) profiles and clinical progression classified by two different N markers using total tau and neurofilament light chain in cerebrospinal fluid, 2022, BMJ Neurology Open
  • Validation of the Japanese version of the Dementia Screening Questionnaire for Individuals with Intellectual Disabilities, 2020, Journal of Intellectual Disability Research
  • Sensitivity to gene dosage and gene expression affects genes with copy number variants observed among neuropsychiatric diseases, 2020, BMC Medical Genomics

Ryozo Kuwano's research covers several main topics, such as:

  • Dementia and Cognitive Impairment Research
  • Frailty in Older Adults
  • Down syndrome and intellectual disability research
  • Alzheimer's disease research and treatments
  • Chronic Disease Management Strategies
  • Bioinformatics and Genomic Networks
  • Epigenetics and DNA Methylation

Main fields of study where Kuwano has contributed include:

  • Medicine
  • Biochemistry, Genetics and Molecular Biology

Subfields frequently addressed in their work are:

  • Molecular Biology
  • Psychiatry and Mental health
  • Geriatrics and Gerontology
  • Public Health, Environmental and Occupational Health
  • Physiology

Collaborations play a notable role in Kuwano's work, with frequent co-authors including:

  • Norikazu Hara
  • Akinori Miyashita
  • Takeshi Ikeuchi
  • Shintaro Takenoshita
  • Seishi Terada

Best Publications

  • A new amyloid β variant favoring oligomerization in Alzheimer's-type dementia

    Takami Tomiyama;Tetsu Nagata;Hiroyuki Shimada;Rie Teraoka

  • Association of HTRA1 mutations and familial ischemic cerebral small-vessel disease

    Shoji Tsuji;Osamu Onodera

  • Molecular cloning of cDNA coding for brain-specific 14-3-3 protein, a protein kinase-dependent activator of tyrosine and tryptophan hydroxylases

    Tohru Ichimura;Toshiaki Isobe;Tsuneo Okuyama;Nobuhiro Takahashi

  • Mutations in COQ2 in familial and sporadic multiple-system atrophy the multiple-system atrophy research collaboration

    Jun Mitsui;Takashi Matsukawa;Hiroyuki Ishiura;Yoko Fukuda;Yoko Fukuda

  • CSF biomarker variability in the Alzheimer's Association quality control program

    Niklas Mattsson;Niklas Mattsson;Ulf Andreasson;Staffan Persson;Maria C. Carrillo

  • The coxsackievirus-adenovirus receptor protein as a cell adhesion molecule in the developing mouse brain

    Takao Honda;Hiroshi Saitoh;Masayoshi Masuko;Takako Katagiri-Abe

  • Expression of Coxsackievirus and Adenovirus Receptor in Hearts of Rats With Experimental Autoimmune Myocarditis

    Masahiro Ito;Makoto Kodama;Masayoshi Masuko;Masayuki Yamaura

  • Genetic association study on in and around the APOE in late-onset Alzheimer disease in Japanese.

    Norihiro Takei;Akinori Miyashita;Tamao Tsukie;Hiroyuki Arai

  • SORL1 is genetically associated with late-onset Alzheimer's disease in Japanese, Koreans and Caucasians

    Akinori Miyashita;Asako Koike;Gyungah Jun;Li-San Wang

  • Transethnic genome-wide scan identifies novel Alzheimer's disease loci

    Gyungah R. Jun;Gyungah R. Jun;Jaeyoon Chung;Jesse Mez;Robert Barber

  • Molecular cloning and the complete nucleotide sequence of cDNA to mRNA for S-100 protein of rat brain

    Ryozo Kuwano;Hiroshi Usui;Toshinaga Maeda;Toshikazu Fukui

  • AlzPathway: a comprehensive map of signaling pathways of Alzheimer’s disease

    Satoshi Mizuno;Risa Iijima;Soichi Ogishima;Masataka Kikuchi

  • Distinct forms of the protein kinase-dependent activator of tyrosine and tryptophan hydroxylases

    Toshiaki Isobe;Tohru Ichimura;Toshiyuki Sunaya;Tsuneo Okuyama

  • S100A6 and S100A11 are specific targets of the calcium- and zinc-binding S100B protein in vivo.

    Jean Christophe Deloulme;Nicole Assard;Gaëlh Ouengue Mbele;Carole Mangin

  • Serum microRNA miR-501-3p as a potential biomarker related to the progression of Alzheimer’s disease

    Norikazu Hara;Masataka Kikuchi;Akinori Miyashita;Hiroyuki Hatsuta

  • A wide spectrum of clinical and brain MRI findings in patients with SLC19A3 mutations

    Kenichiro Yamada;Kiyokuni Miura;Kenju Hara;Motomasa Suzuki

  • A mutant PSEN1 causes dementia with Lewy bodies and variant Alzheimer's disease.

    Atsushi Ishikawa;Yue-Shan Piao;Akinori Miyashita;Ryozo Kuwano

  • Expression of vascular endothelial growth factor in capillary hemangioblastoma

    K. Morii;R. Tanaka;K. Washiyama;T. Kumanishi

  • Distinct molecular mechanisms of HTRA1 mutants in manifesting heterozygotes with CARASIL

    Hiroaki Nozaki;Taisuke Kato;Megumi Nihonmatsu;Yohei Saito

  • Meta-analysis of genome-wide association scans for genetic susceptibility to endometriosis in Japanese population.

    Sosuke Adachi;Atsushi Tajima;Jinhua Quan;Kazufumi Haino

Frequent Co-Authors

Yasuo Takahashi
Yasuo Takahashi Niigata University
Takeshi Ikeuchi
Takeshi Ikeuchi Niigata University
Yasuo Ihara
Yasuo Ihara Doshisha University
Takeshi Iwatsubo
Takeshi Iwatsubo University of Tokyo
Osamu Onodera
Osamu Onodera Niigata University
Akiyoshi Kakita
Akiyoshi Kakita Niigata University
Kenji Ishii
Kenji Ishii Nippon Medical School
Hiroyuki Arai
Hiroyuki Arai University of Tokyo
Hitoshi Takahashi
Hitoshi Takahashi Niigata University
Shoji Tsuji
Shoji Tsuji University of Tokyo

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