Caroline Graff mainly focuses on Alzheimer's disease, Genetics, Pathology, Genome-wide association study and Dementia. Her Alzheimer's disease study improves the overall literature in Disease. Her work in Genetics is not limited to one particular discipline; it also encompasses Frontotemporal lobar degeneration.
Her work deals with themes such as Case-control study and Locus, which intersect with Genome-wide association study. The study incorporates disciplines such as rs6265, Gerontology, Cognitive skill, Cognition and Neuroimaging in addition to Dementia. As a part of the same scientific study, she usually deals with the Single-nucleotide polymorphism, concentrating on Age of onset and frequently concerns with SORL1, PICALM, Granulin and Gene polymorphism.
Frontotemporal dementia, Genetics, Disease, Internal medicine and Alzheimer's disease are her primary areas of study. In her study, which falls under the umbrella issue of Frontotemporal dementia, Neurodegeneration is strongly linked to Atrophy. Caroline Graff has researched Disease in several fields, including Mutation and Psychiatry, Neurology.
Her Alzheimer's disease study combines topics in areas such as Bioinformatics and Amyloid. Her biological study spans a wide range of topics, including Cognition and Gerontology. Caroline Graff interconnects Apolipoprotein E, Allele frequency and Age of onset in the investigation of issues within Genetic association.
Caroline Graff spends much of her time researching Frontotemporal dementia, Disease, C9orf72, Internal medicine and Atrophy. Caroline Graff combines subjects such as Neurodegeneration, Cognition, Neuroscience and Cohort with her study of Frontotemporal dementia. Her Disease research includes themes of Genome-wide association study and Gene.
Caroline Graff focuses mostly in the field of Genome-wide association study, narrowing it down to matters related to Genetic predisposition and, in some cases, Genetic association. Her Genetics research integrates issues from Alzheimer's disease and TREM2. Her studies deal with areas such as Phenotype and Molecular biology as well as Alzheimer's disease.
Caroline Graff mainly focuses on Frontotemporal dementia, C9orf72, Internal medicine, Atrophy and Disease. The C9orf72 study combines topics in areas such as C9orf72 Protein, Neuroscience and Age of onset. Her Internal medicine study incorporates themes from Endocrinology and Oncology.
Her study in Disease is interdisciplinary in nature, drawing from both Phenotype, Genetics, Gene, Genome-wide association study and Bioinformatics. Her Genetic heterogeneity research incorporates elements of Single-nucleotide polymorphism and Genetic association. The concepts of her Alzheimer's disease study are interwoven with issues in Stage and Computational biology.
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Mild cognitive impairment--beyond controversies, towards a consensus: report of the International Working Group on Mild Cognitive Impairment.
B. Winblad;K. Palmer;Miia Kivipelto;V. Jelic.
Journal of Internal Medicine (2004)
Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer's disease
Jean-Charles Lambert;Jean-Charles Lambert;Jean-Charles Lambert;Carla A Ibrahim-Verbaas;Denise Harold;Adam C Naj.
Nature Genetics (2013)
Defeating Alzheimer's disease and other dementias: a priority for European science and society
Bengt Winblad;Bengt Winblad;Philippe Amouyel;Sandrine Andrieu;Clive Ballard.
Lancet Neurology (2016)
Gene-wide analysis detects two new susceptibility genes for Alzheimer's disease
Valentina Escott-Price;Céline Bellenguez;Li-San Wang;Seung-Hoan Choi.
PLOS ONE (2014)
Impaired insulin secretion and β-cell loss in tissue-specific knockout mice with mitochondrial diabetes
José P. Silva;Martin Köhler;Caroline Graff;Anders Oldfors.
Nature Genetics (2000)
Dilated cardiomyopathy and atrioventricular conduction blocks induced by heart-specific inactivation of mitochondrial DNA gene expression
Jianming Wang;H. Wilhelmsson;C. Graff;Hong Li.
Nature Genetics (1999)
Rare coding variants in PLCG2, ABI3, and TREM2 implicate microglial-mediated innate immunity in Alzheimer's disease
Rebecca Sims;Sven J. Van Der Lee;Adam C. Naj;Céline Bellenguez;Céline Bellenguez.
Nature Genetics (2017)
Presymptomatic cognitive and neuroanatomical changes in genetic frontotemporal dementia in the Genetic Frontotemporal dementia Initiative (GENFI) study: a cross-sectional analysis
Jonathan D Rohrer;Jennifer M Nicholas;Jennifer M Nicholas;David M Cash;John van Swieten.
Lancet Neurology (2015)
Modulation of the endoplasmic reticulum–mitochondria interface in Alzheimer’s disease and related models
Louise Hedskog;Catarina Moreira Pinho;Riccardo Filadi;Annica Rönnbäck.
Proceedings of the National Academy of Sciences of the United States of America (2013)
Increased mitochondrial mass in mitochondrial myopathy mice.
Anna Wredenberg;Rolf Wibom;Hans Wilhelmsson;Caroline Graff.
Proceedings of the National Academy of Sciences of the United States of America (2002)
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