World's Best Scientists 2026 revealed!

D-Index & Metrics

Chemistry

D-Index
49
Citations
8199
World Ranking
14875
National Ranking
268

Overview

Håkan Wikström is affiliated with the University of Groningen in the Netherlands. Their research spans multiple domains within engineering and pharmaceutics, with a particular focus on pharmaceutical science and computational mechanics. The core areas of investigation include drug solubility and delivery systems, granular flow and fluidized beds, and protein purification and stability.

Their recent publications cover a variety of topics related to pharmaceutical manufacturing and material behavior. Notable works include:

  • Comparison between twin-screw and high-shear granulation - The effect of filler and active pharmaceutical ingredient on the granule and tablet properties, 2020, published in Powder Technology
  • Twin-screw granulation and high-shear granulation: The influence of mannitol grade on granule and tablet properties, 2020, International Journal of Pharmaceutics
  • Powder flow from an intermediate bulk container - Discharge predictions and experimental evaluation, 2021, International Journal of Pharmaceutics
  • Optical porosimetry by gas in scattering media absorption spectroscopy (GASMAS) applied to roller compaction ribbons, 2020, International Journal of Pharmaceutics
  • Faster to First-time-in-Human: Prediction of the liquid solid ratio for continuous wet granulation, 2022, European Journal of Pharmaceutical Sciences

The venues where the researcher frequently publishes are predominantly specialized journals in pharmaceutics and pharmaceutical sciences. Frequent publication venues include:

  • International Journal of Pharmaceutics
  • European Journal of Pharmaceutical Sciences
  • SSRN Electronic Journal
  • Powder Technology
  • Journal of Pharmaceutical Sciences

Håkan Wikström collaborates with several recurring coauthors, among them are Pirjo Tajarobi, Jarkko Ketolainen, Luis Martín de Juan, Joona Sorjonen, and Andrew Megarry. These partnerships indicate a collaborative research environment spanning pharmaceutical formulation and process engineering.

Their research fields primarily cover:

  • Engineering
  • Pharmacology, Toxicology and Pharmaceutics

Subfields of study related to their work include:

  • Pharmaceutical Science
  • Computational Mechanics
  • Molecular Biology
  • Analytical Chemistry
  • Biomedical Engineering

Main topics of research encompass:

  • Drug Solubility and Delivery Systems
  • Granular flow and fluidized beds
  • Protein purification and stability
  • Fluid Dynamics and Heat Transfer
  • Pharmaceutical Quality and Counterfeiting
  • Analytical Methods in Pharmaceuticals
  • Advanced Drug Delivery Systems

Best Publications

  • 8-hydroxy-2-(di-n-propylamino)tetralin, 8-OH-DPAT, a potent and selective simplified ergot congener with central 5-HT-receptor stimulating activity

    S. Hjorth;A. Carlsson;P. Lindberg;D. Sanchez

  • 8-Hydroxy-2-(di-n-propylamino)tetralin, a new centrally acting 5-hydroxytryptamine receptor agonist

    L E Arvidsson;U Hacksell;J L Nilsson;S Hjorth

  • Autoradiographic localization of 5-HT1A receptors in the post-mortem human brain using [3H]WAY-100635 and [11C]WAY-100635

    H Hall;C Lundkvist;C Halldin;L Farde

  • Novel antipsychotic drugs share high affinity for σ receptors

    Brian L. Largent;Håkan Wikström;Adele M. Snowman;Solomon H. Snyder

  • 3-PPP, a new centrally acting DA-receptor agonist with selectivity for autoreceptors

    S. Hjorth;A. Carlsson;H. Wikström;P. Lindberg

  • Comparison between electrochemistry/mass spectrometry and cytochrome P450 catalyzed oxidation reactions.

    Ulrik Jurva;Håkan V. Wikström;Lars Weidolf;Andries P. Bruins

  • Central dopamine receptor agonist and antagonist actions of the enantiomers of 3-PPP.

    S. Hjorth;A. Carlsson;D. Clark;K. Svensson

  • Inactivation of 5-HT2C receptors potentiates consequences of serotonin reuptake blockade

    Thomas I F H Cremers;Marco Giorgetti;Fokko J Bosker;Sandra Hogg

  • Synthesis and pharmacological evaluation of thiopyran analogues of the dopamine D3 receptor-selective agonist (4aR,10bR)-(+)-trans-3,4,4a,10b-tetrahydro-4-n-propyl-2H,5H-[1]benzopyrano[4,3-b]-1,4-oxazin-9-ol (PD 128907)

    LA van Vliet;N Rodenhuis;D Dijkstra;H Wikstrom

  • Autoradiographic localisation of D3-dopamine receptors in the human brain using the selective D3-dopamine receptor agonist (+)-[3H]PD 128907

    Håkan Hall;Christer Halldin;Durk Dijkstra;Håkan Wikström

  • Pharmacological aspects of R-( + )-7-OH-DPAT, a putative dopamine D3 receptor ligand

    Geert Damsma;Tjibbe Bottema;Ben H.C. Westerink;Pieter G. Tepper

  • Substituted (S)-phenylpiperidines and rigid congeners as preferential dopamine autoreceptor antagonists: synthesis and structure-activity relationships.

    C. Sonesson;Chiu-Hong Lin;L. Hansson;N. Waters

  • Antipsychotic drugs classified by their effects on the release of dopamine and noradrenaline in the prefrontal cortex and striatum

    B.H. Westerink;Y. Kawahara;P.A.J. de Boer;C. Geels

  • Effect of amphetamine on dopamine D2 receptor binding in nonhuman primate brain: A comparison of the agonist radioligand [11C]MNPA and antagonist [11C]raclopride

    Nicholas Seneca;Sjoerd J. Finnema;Lars Farde;Balázs Gulyás

  • N-Alkylated 2-aminotetralins: central dopamine-receptor stimulating activity.

    Hacksell U;Svensson U;Nilsson Jl;Hjorth S

  • Stereochemistry-Dependent Cytotoxicity of Some Artemisinin Derivatives

    A.C Beekman;A.R.W. Barentsen;Herman Woerdenbag;W van Uden

  • In vitro mimicry of metabolic oxidation reactions by electrochemistry/mass spectrometry

    Ulrik Jurva;Håkan V. Wikström;Andries P. Bruins

  • 3-Phenylpiperidines. Central dopamine-autoreceptor stimulating activity.

    Hacksell U;Arvidsson Le;Svensson U;Nilsson Jl

  • Acute and chronic effects of citalopram on postsynaptic 5-hydroxytryptamine(1A) receptor-mediated feedback: a microdialysis study in the amygdala.

    Fokko Bosker;Thomas Cremers;M.E. Jongsma;Ben Westerink

  • Artemisinin-derived sesquiterpene lactones as potential antitumour compounds: cytotoxic action against bone marrow and tumour cells.

    AC Beekman;PK Wierenga;Herman Woerdenbag;W Van Uden

Frequent Co-Authors

Christer Halldin
Christer Halldin Karolinska Institute
Arvid Carlsson
Arvid Carlsson University of Gothenburg
Lars Farde
Lars Farde Karolinska Institute
Uli Hacksell
Uli Hacksell Acadia Pharmaceuticals (United States)
Stephan Hjorth
Stephan Hjorth University of Gothenburg
Frode Rise
Frode Rise University of Oslo
Robert B. Innis
Robert B. Innis National Institutes of Health
Victor W. Pike
Victor W. Pike National Institutes of Health
Sami S. Zoghbi
Sami S. Zoghbi National Institutes of Health
Håkan Hall
Håkan Hall Karolinska Institute

If you think any of the details on this page are incorrect, let us know.

Report an issue

We appreciate your kind effort to assist us to improve this page, it would be helpful providing us with as much detail as possible in the text box below:

Related Online Degrees & Career Pathways

Studying Chemistry in the USA opens doors to diverse career paths, many of which can be pursued through specialized online degrees. For those interested in legal aspects of science, exploring a paralegal salary through related degrees offers a unique blend of law and science, often leading to rewarding roles in intellectual property or environmental law.

Another promising pathway is becoming a pharmaceutical sales representative. Understanding chemistry is crucial for success in this field, and the guide on pharma sales rep salary and career paths provides insight into educational requirements and earning potential.

For those aiming higher in the pharmaceutical industry, the educational track to becoming a pharmacist is rigorous but rewarding. Detailed information about pharmacist education requirements highlights the degree programs and certifications needed for this vital healthcare profession.

Finally, a niche yet critical role is that of an autopsy technician. Chemistry knowledge supports the forensic and analytical skills needed; learn more about how to become an autopsy technician, including necessary education, salary expectations, and job outlook.

Best Scientists Citing Håkan Wikström

Trending Scientists

Recently Published Articles