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Chemistry

D-Index
78
Citations
20787
World Ranking
3824
National Ranking
1223

Medicine

D-Index
84
Citations
22484
World Ranking
15246
National Ranking
7690

Overview

Victor W. Pike is affiliated with the National Institutes of Health in the United States. Their research primarily spans the fields of Medicine and Biochemistry, Genetics and Molecular Biology, with a significant focus on Molecular Biology, Radiology, Nuclear Medicine and Imaging, Pharmaceutical Science, Pharmacology, and Cellular and Molecular Neuroscience.

The scientist's work covers various main topics including Medical Imaging Techniques and Applications, Fluorine in Organic Chemistry, Radiopharmaceutical Chemistry and Applications, Inflammatory mediators and NSAID effects, Neuroscience and Neuropharmacology Research, Phosphodiesterase function and regulation, and Estrogen and related hormone effects.

Frequent coauthors collaborating with Victor W. Pike include:

  • Robert B. Innis
  • Sami S. Zoghbi
  • Sanjay Telu
  • Jeih-San Liow
  • Cheryl L. Morse

Key venues where Victor W. Pike has frequently published are:

  • Biological Psychiatry
  • Journal of Nuclear Medicine
  • Nuclear Medicine and Biology
  • Journal of Cerebral Blood Flow & Metabolism
  • Journal of Medicinal Chemistry

Some of the recent papers authored or coauthored by Victor W. Pike include:

  • Guidelines for the content and format of PET brain data in publications and archives: A consensus paper, 2020, Journal of Cerebral Blood Flow & Metabolism
  • PET measurement of cyclooxygenase-2 using a novel radioligand: upregulation in primate neuroinflammation and first-in-human study, 2020, Journal of Neuroinflammation
  • First-in-human evaluation of [11C]PS13, a novel PET radioligand, to quantify cyclooxygenase-1 in the brain, 2020, European Journal of Nuclear Medicine and Molecular Imaging
  • [11C]deschloroclozapine is an improved PET radioligand for quantifying a human muscarinic DREADD expressed in monkey brain, 2021, Journal of Cerebral Blood Flow & Metabolism
  • PET ligands [ 18 F]LSN3316612 and [ 11 C]LSN3316612 quantify O-linked-β-N-acetyl-glucosamine hydrolase in the brain, 2020, Science Translational Medicine

Best Publications

  • Reversible and regionally selective downregulation of brain cannabinoid CB1 receptors in chronic daily cannabis smokers

    Hirvonen J;Goodwin Rs;Li Ct;Terry Ge

  • PET radiotracers: crossing the blood-brain barrier and surviving metabolism

    Victor W. Pike

  • Chemistry with [18F]Fluoride Ion

    Lisheng Cai;Shuiyu Lu;Victor W. Pike

  • Mixed-Affinity Binding in Humans with 18-kDa Translocator Protein Ligands

    David R.J. Owen;Roger N. Gunn;Eugenii A. Rabiner;Idriss Bennacef

  • In vivo radioligand binding to translocator protein correlates with severity of Alzheimer’s disease

    William C. Kreisl;Chul Hyoung Lyoo;Meghan McGwier;Joseph Snow

  • Comparison of [(11)C]-(R)-PK 11195 and [(11)C]PBR28, two radioligands for translocator protein (18 kDa) in human and monkey: Implications for positron emission tomographic imaging of this inflammation biomarker.

    William C. Kreisl;Masahiro Fujita;Yota Fujimura;Yota Fujimura;Nobuyo Kimura

  • A genetic polymorphism for translocator protein 18 kDa affects both in vitro and in vivo radioligand binding in human brain to this putative biomarker of neuroinflammation.

    William C Kreisl;Kimberly J Jenko;Christina S Hines;Chul Hyoung Lyoo

  • Autoradiographic localization of 5-HT1A receptors in the post-mortem human brain using [3H]WAY-100635 and [11C]WAY-100635

    H Hall;C Lundkvist;C Halldin;L Farde

  • Tracer Kinetic Modeling of the 5-HT1AReceptor Ligand [carbonyl-11C]WAY-100635 for PET

    Roger N. Gunn;Peter A. Sargent;Christopher J. Bench;Eugenii A. Rabiner

  • Exquisite delineation of 5-HT1A receptors in human brain with PET and [carbonyl-11C]WAY-100635

    Victor W. Pike;Julie A. McCarron;Adriaan A. Lammertsma;Safiye Osman

  • Cerebellum Can Serve As a Pseudo-Reference Region in Alzheimer Disease to Detect Neuroinflammation Measured with PET Radioligand Binding to Translocator Protein.

    Chul Hyoung Lyoo;Masamichi Ikawa;Jeih San Liow;Sami S. Zoghbi

  • Recommendations for a practical production of [11C]methyl iodide☆

    C. Crouzel;B. Långström;V.W. Pike;H.H. Coenen

  • Consensus nomenclature rules for radiopharmaceutical chemistry - Setting the record straight.

    Heinz H. Coenen;Antony D. Gee;Michael Adam;Gunnar Antoni

  • Synthesis of the enantiomers of [N-methyl-11C]PK 11195 and comparison of their behaviours as radioligands for PK binding sites in rats.

    Farah Shah;Susan P. Hume;Victor W. Pike;Sharon Ashworth

  • Kinetic analysis in healthy humans of a novel positron emission tomography radioligand to image the peripheral benzodiazepine receptor, a potential biomarker for inflammation.

    Masahiro Fujita;Masao Imaizumi;Sami S. Zoghbi;Yota Fujimura

  • Synthesis and evaluation in monkey of two sensitive 11C-labeled aryloxyanilide ligands for imaging brain peripheral benzodiazepine receptors in vivo.

    Emmanuelle Briard;Sami S. Zoghbi;Masao Imaizumi;Jonathan P. Gourley

  • PET imaging of the dopamine transporter with 18F-FECNT: a polar radiometabolite confounds brain radioligand measurements.

    Sami S. Zoghbi;H. Umesha Shetty;Masanori Ichise;Masahiro Fujita

  • The "specific" P-glycoprotein inhibitor Tariquidar is also a substrate and an inhibitor for breast cancer resistance protein (BCRP/ABCG2).

    Pavitra Kannan;Pavitra Kannan;Sanjay Telu;Suneet Shukla;Suresh V. Ambudkar

  • Recommendations for fluorine-18 production

    Marcel Guillaume;André Luxen;Bruno Nebeling;Mario Argentini

  • Fast and high-yield microreactor syntheses of ortho-substituted [(18)F]fluoroarenes from reactions of [(18)F]fluoride ion with diaryliodonium salts.

    Joong-Hyun Chun;Shuiyu Lu;Yong-Sok Lee;Victor W. Pike

Frequent Co-Authors

Robert B. Innis
Robert B. Innis National Institutes of Health
Sami S. Zoghbi
Sami S. Zoghbi National Institutes of Health
Christer Halldin
Christer Halldin Karolinska Institute
Lars Farde
Lars Farde Karolinska Institute
Jussi Hirvonen
Jussi Hirvonen Turku University Hospital
Antony D. Gee
Antony D. Gee King's College London
Balázs Gulyás
Balázs Gulyás Nanyang Technological University
Vanessa Cropley
Vanessa Cropley University of Melbourne
Heinz H. Coenen
Heinz H. Coenen Forschungszentrum Jülich
Håkan Wikström
Håkan Wikström University of Groningen

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