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Biology and Biochemistry

D-Index
64
Citations
14371
World Ranking
9686
National Ranking
256

Overview

Michael Kassiou is affiliated with the University of Sydney in Australia. Their research primarily spans the fields of Medicine and Biochemistry, Genetics and Molecular Biology, with significant contributions to subfields such as Molecular Biology, Physiology, Neurology, Cellular and Molecular Neuroscience, and Organic Chemistry.

The scientist's work covers various research topics including:

  • Adenosine and Purinergic Signaling
  • Alzheimer's disease research and treatments
  • Neuroinflammation and Neurodegeneration Mechanisms
  • Neuroscience and Neuropharmacology Research
  • Cannabis and Cannabinoid Research
  • Pharmacological Receptor Mechanisms and Effects
  • Amyotrophic Lateral Sclerosis Research

Michael Kassiou has published numerous papers, among which the following are notable:

  • Low intrinsic efficacy for G protein activation can explain the improved side effect profiles of new opioid agonists, 2020, Science Signaling
  • Late-stage Functionalization for Improving Drug-like Molecular Properties, 2023, Chemical Reviews
  • Altered serum protein levels in frontotemporal dementia and amyotrophic lateral sclerosis indicate calcium and immunity dysregulation, 2020, Scientific Reports
  • Prodromal neuroinflammatory, cholinergic and metabolite dysfunction detected by PET and MRS in the TgF344-AD transgenic rat model of AD: a collaborative multi-modal study, 2021, Theranostics
  • Recent Scaffold Hopping Applications in Central Nervous System Drug Discovery, 2022, Journal of Medicinal Chemistry

The venues where Michael Kassiou frequently publishes include:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • ACS Chemical Neuroscience
  • International Journal of Molecular Sciences
  • Scientific Reports
  • Theranostics

The scientist has collaborated extensively with co-authors such as:

  • Eryn L. Werry
  • Jonathan J. Danon
  • Andrew P. Montgomery
  • Tristan A. Reekie
  • Lars M. Ittner

Michael Kassiou is also an author of book publications, including work published by Frontiers Media, notably titled "Medicinal and Pharmaceutical Chemistry Editor's Pick 2024" slated for release in 2025.

Best Publications

  • Boron in drug discovery: carboranes as unique pharmacophores in biologically active compounds.

    Fatiah Issa;Michael Kassiou;Louis M. Rendina

  • Small animal SPECT and its place in the matrix of molecular imaging technologies.

    Steven R Meikle;Peter Kench;Michael Kassiou;Michael Kassiou;Richard B Banati

  • DPA-714, a New Translocator Protein–Specific Ligand: Synthesis, Radiofluorination, and Pharmacologic Characterization

    Michelle L James;Roger R Fulton;Johnny Vercoullie;David J Henderson

  • Pharmacology of Valinate and tert-Leucinate Synthetic Cannabinoids 5F-AMBICA, 5F-AMB, 5F-ADB, AMB-FUBINACA, MDMB-FUBINACA, MDMB-CHMICA, and Their Analogues.

    Samuel D. Banister;Mitchell Longworth;Richard Kevin;Shivani Sachdev

  • Recent Developments in TSPO PET Imaging as A Biomarker of Neuroinflammation in Neurodegenerative Disorders.

    Eryn L. Werry;Fiona M. Bright;Olivier Piguet;Lars M. Ittner

  • Low intrinsic efficacy for G protein activation can explain the improved side effect profiles of new opioid agonists.

    Alexander Gillis;Arisbel B. Gondin;Andrea Kliewer;Julie Sanchez;Julie Sanchez

  • Comparative Evaluation of the Translocator Protein Radioligands 11C-DPA-713, 18F-DPA-714, and 11C-PK11195 in a Rat Model of Acute Neuroinflammation

    Fabien Chauveau;Nadja Van Camp;Frédéric Dollé;Bertrand Kuhnast

  • Neuroinflammation in frontotemporal dementia.

    Fiona Bright;Eryn L. Werry;Carol Dobson-Stone;Carol Dobson-Stone;Olivier Piguet;Olivier Piguet

  • Brain inflammation is induced by co-morbidities and risk factors for stroke

    Caroline Drake;Hervé Boutin;Matthew S. Jones;Adam Denes

  • Neuroinflammation and brain atrophy in former NFL players: An in vivo multimodal imaging pilot study

    Jennifer M. Coughlin;Yuchuan Wang;Cynthia A. Munro;Shuangchao Ma

  • Pharmacology of Indole and Indazole Synthetic Cannabinoid Designer Drugs AB-FUBINACA, ADB-FUBINACA, AB-PINACA, ADB-PINACA, 5F-AB-PINACA, 5F-ADB-PINACA, ADBICA, and 5F-ADBICA

    Samuel D. Banister;Samuel D. Banister;Michael Moir;Jordyn Stuart;Richard C. Kevin

  • Evaluation of the PBR/TSPO Radioligand [18F]DPA-714 in a Rat Model of Focal Cerebral Ischemia

    Abraham Martín;Raphaël Boisgard;Benoit Thézé;Nadja Van Camp

  • Effects of Bioisosteric Fluorine in Synthetic Cannabinoid Designer Drugs JWH-018, AM-2201, UR-144, XLR-11, PB-22, 5F-PB-22, APICA, and STS-135

    Samuel D. Banister;Jordyn Stuart;Richard C. Kevin;Amelia Edington

  • Translational evaluation of translocator protein as a marker of neuroinflammation in schizophrenia

    T Notter;J M Coughlin;T Gschwind;U Weber-Stadlbauer

  • The Translocator Protein

    Alana M. Scarf;Michael Kassiou

  • 11C-DPA-713: A Novel Peripheral Benzodiazepine Receptor PET Ligand for In Vivo Imaging of Neuroinflammation

    Hervé Boutin;Fabien Chauveau;Cyrille Thominiaux;Marie Claude Grégoire

  • Developing a preclinical model of Parkinson's disease: a study of behaviour in rats with graded 6-OHDA lesions

    L. Truong;H. Allbutt;M. Kassiou;M. Kassiou;J.M. Henderson

  • Positron emission tomography imaging of neuroinflammation.

    Annachiara Cagnin;Michael Kassiou;Steve R. Meikle;Richard B. Banati

  • In vivo markers of inflammatory response in recent-onset schizophrenia: a combined study using [(11)C]DPA-713 PET and analysis of CSF and plasma.

    J M Coughlin;Y Wang;E B Ambinder;R E Ward

  • Determination and reduction of translocator protein (TSPO) ligand rs6971 discrimination.

    Renee Sokias;Eryn L. Werry;Sook W. Chua;Tristan A. Reekie

Frequent Co-Authors

Frédéric Dollé
Frédéric Dollé French Alternative Energies and Atomic Energy Commission (CEA)
Iain S. McGregor
Iain S. McGregor University of Sydney
Lars M. Ittner
Lars M. Ittner Macquarie University
Denis Guilloteau
Denis Guilloteau François Rabelais University
Robert F. Dannals
Robert F. Dannals Johns Hopkins University School of Medicine
MacDonald J. Christie
MacDonald J. Christie University of Sydney
Martin G. Pomper
Martin G. Pomper Johns Hopkins University School of Medicine
Matthew C. Kiernan
Matthew C. Kiernan Royal Prince Alfred Hospital
Richard B. Banati
Richard B. Banati University of Sydney
Olivier Piguet
Olivier Piguet University of Sydney

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