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Overview

Denis Guilloteau is affiliated with François Rabelais University in France and has produced research primarily in the field of Medicine. Their work spans multiple subfields, including Radiology, Nuclear Medicine and Imaging, Neurology, Cellular and Molecular Neuroscience, Pharmaceutical Science, and Materials Chemistry.

Guilloteau's research focuses on areas such as Medical Imaging Techniques and Applications, Radiopharmaceutical Chemistry and Applications, Neuroscience and Neuropharmacology Research, Chemical Reactions and Isotopes, Neurological Disorders and Treatments, Parkinson's Disease Mechanisms and Treatments, and Functional Brain Connectivity Studies.

Among their recent papers are the following:

  • Usefulness of PET With [18F]LBT-999 for the Evaluation of Presynaptic Dopaminergic Neuronal Loss in a Clinical Environment, 2020, Frontiers in Neurology
  • Imaging of dopamine transporter with [18F]LBT-999: initial evaluation in healthy volunteers, 2022, The Quarterly Journal of Nuclear Medicine and Molecular Imaging
  • Fully automated radiosynthesis of [18F]LBT999 on TRACERlab FXFN and AllinOne modules, a PET radiopharmaceutical for imaging the dopamine transporter in human brain, 2020, EJNMMI Radiopharmacy and Chemistry
  • Development and preclinical evaluation of [18F]FBVM as a new potent PET tracer for vesicular acetylcholine transporter, 2022, European Journal of Medicinal Chemistry
  • Médicaments radiopharmaceutiques: du diagnostic au théranostique des tumeurs neuroendocrines, 2021, Médecine Nucléaire

Denis Guilloteau frequently collaborates with a set of coauthors who have contributed significantly to their research. These coauthors include Johnny Vercouillie, Patrick Emond, Nicolas Arlicot, Serge Maïa, and Jean-Bernard Deloye.

Their work appears in scientific venues such as Frontiers in Neurology, The Quarterly Journal of Nuclear Medicine and Molecular Imaging, EJNMMI Radiopharmacy and Chemistry, European Journal of Medicinal Chemistry, and Médecine Nucléaire.

Best Publications

  • Relationship between the Appearance of Symptoms and the Level of Nigrostriatal Degeneration in a Progressive 1-Methyl-4-Phenyl-1,2,3,6-Tetrahydropyridine-Lesioned Macaque Model of Parkinson's Disease

    Erwan Bezard;Erwan Bezard;Sandra Dovero;Caroline Prunier;Paula Ravenscroft

  • α-Linolenic Acid Dietary Deficiency Alters Age-Related Changes of Dopaminergic and Serotoninergic Neurotransmission in the Rat Frontal Cortex

    Sylvie Delion;Sylvie Chalon;Denis Guilloteau;Jean-Claude Besnard

  • Chronic dietary α-linolenic acid deficiency alters dopaminergic and serotoninergic neurotransmission in rats

    Sylvie Delion;Sylvie Chalon;Josiane Hérault;Denis Guilloteau

  • Region-specific hierarchy between atrophy, hypometabolism, and β-amyloid (Aβ) load in Alzheimer's disease dementia.

    Renaud La Joie;Audrey Perrotin;Louisa Barré;Caroline Hommet;Caroline Hommet

  • Plasma fatty acid levels in autistic children.

    S. Vancassel;G. Durand;C. Barthélémy;B. Lejeune

  • Dietary Fish Oil Affects Monoaminergic Neurotransmission and Behavior in Rats

    Sylvie Chalon;Sylvie Delion-Vancassel;Catherine Belzung;Denis Guilloteau

  • Using PET with 18F-AV-45 (florbetapir) to quantify brain amyloid load in a clinical environment

    V. Camus;P. Payoux;P. Payoux;L. Barré;L. Barré;B. Desgranges;B. Desgranges;B. Desgranges

  • The dopamine mesocorticolimbic pathway is affected by deficiency in n−3 polyunsaturated fatty acids

    Luc Zimmer;Sylvie Vancassel;Sylvain Cantagrel;Patrick Breton

  • Modification of dopamine neurotransmission in the nucleus accumbens of rats deficient in n-3 polyunsaturated fatty acids.

    Luc Zimmer;Sylvie Delion-Vancassel;Georges Durand;Denis Guilloteau

  • Molecular Imaging of Microglial Activation in Amyotrophic Lateral Sclerosis

    Philippe Corcia;Clovis Tauber;Clovis Tauber;Johnnie Vercoullie;Johnnie Vercoullie;Nicolas Arlicot;Nicolas Arlicot

  • Polyunsaturated fatty acids and cerebral function: focus on monoaminergic neurotransmission.

    Sylvie Chalon;Sylvie Vancassel;Luc Zimmer;Denis Guilloteau

  • Chronic n-3 polyunsaturated fatty acid deficiency alters dopamine vesicle density in the rat frontal cortex.

    L Zimmer;S Delpal;D Guilloteau;J Aı̈oun

  • Partial recovery of dopaminergic pathway after graft of adult mesenchymal stem cells in a rat model of Parkinson's disease.

    Gaëlle Bouchez;Luc Sensebé;Patrick Vourc’h;Patrick Vourc’h;Lucette Garreau;Lucette Garreau

  • Translocator Protein-18 kDa (TSPO) Positron Emission Tomography (PET) Imaging and Its Clinical Impact in Neurodegenerative Diseases.

    Anne-Claire Dupont;Bérenger Largeau;Maria Joao Santiago Ribeiro;Denis Guilloteau

  • Behavior and serotonergic disorders in rats exposed prenatally to valproate: a model for autism.

    Diane Dufour-Rainfray;Patrick Vourc’h;Anne-Marie Le Guisquet;Anne-Marie Le Guisquet;Lucette Garreau;Lucette Garreau

  • Reversibility of n-3 fatty acid deficiency-induced changes in dopaminergic neurotransmission in rats: critical role of developmental stage.

    Ercem Kodas;Sylvie Vancassel;Bernard Lejeune;Denis Guilloteau

  • Age-related changes in phospholipid fatty acid composition and monoaminergic neurotransmission in the hippocampus of rats fed a balanced or an n-3 polyunsaturated fatty acid-deficient diet

    Sylvie Delion;Sylvie Chalon;Denis Guilloteau;Bernard Lejeune

  • Subjective cognitive decline in cognitively normal elders from the community or from a memory clinic: Differential affective and imaging correlates.

    Audrey Perrotin;Renaud La Joie;Vincent de La Sayette;Louisa Barré;Louisa Barré;Louisa Barré

  • Synthesis and ligand binding of nortropane derivatives : N-substituted 2β-carbomethoxy-3β-(4'-iodophenyl)nortropane and N-(3-iodoprop-(2E)-enyl)-2β-carbomethoxy-3β-(3',4'-disubstituted phenyl)nortropane. New high-affinity and selective compounds for the dopamine transporter

    Patrick Emond;Lucette Garreau;Sylvie Chalon;Miriam Boazi

  • Chronic n-3 polyunsaturated fatty acid diet-deficiency acts on dopamine metabolism in the rat frontal cortex: a microdialysis study.

    L Zimmer;S Hembert;G Durand;P Breton

Frequent Co-Authors

Catherine Belzung
Catherine Belzung François Rabelais University
Francis Eustache
Francis Eustache Université de Caen Normandie
Lars Farde
Lars Farde Karolinska Institute
Gaël Chételat
Gaël Chételat Université de Caen Normandie
Michèle Allard
Michèle Allard Centre national de la recherche scientifique, CNRS
Håkan Hall
Håkan Hall Karolinska Institute
Balázs Gulyás
Balázs Gulyás Nanyang Technological University
Andrea Varrone
Andrea Varrone Karolinska Institute
Christian E. Gross
Christian E. Gross University of Bordeaux
François Tison
François Tison University of Bordeaux

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