World's Best Scientists 2026 revealed!

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Immunology

D-Index
82
Citations
19386
World Ranking
1532
National Ranking
766

Medicine

D-Index
82
Citations
19412
World Ranking
16325
National Ranking
8210

Overview

Jerry Y. Niederkorn is affiliated with The University of Texas Southwestern Medical Center in the United States. Their research primarily focuses on the biology and immunology of the ocular surface, with special attention to corneal health and related immune responses.

The scientist's recent publications cover a range of topics relevant to ocular surface diseases and immune mechanisms. Key papers include:

  • The biology of Acanthamoeba keratitis, 2020, published in Experimental Eye Research
  • "Corneal Nerves, CD11c+ Dendritic Cells and Their Impact on Ocular Immune Privilege", 2021, published in Frontiers in Immunology
  • Corneal Nerve Ablation Abolishes Ocular Immune Privilege by Downregulating CD103 on T Regulatory Cells, 2020, published in Investigative Ophthalmology & Visual Science
  • Immunologic basis for development of keratoconjunctivitis sicca in systemic autoimmune diseases: Role of innate immune sensors, 2024, published in The Ocular Surface

Their collaborative work involves several frequent coauthors, including:

  • Michael E. Stern
  • Argyrios N. Theofilopoulos
  • Philipp Steven
  • Robert I. Fox
  • Margarita Calonge

The scientist publishes regularly in several specialized venues, such as:

  • Experimental Eye Research
  • Frontiers in Immunology
  • The Ocular Surface
  • Investigative Ophthalmology & Visual Science

Jerry Y. Niederkorn's work spans multiple fields, predominantly Medicine, with additional focus on Biochemistry, Genetics and Molecular Biology. Their subfield contributions include Public Health, Environmental and Occupational Health, Endocrinology, Immunology, Neurology, and Rheumatology.

The main scientific topics addressed in their research cover:

  • Ocular Surface and Contact Lens
  • Legionella and Acanthamoeba research
  • Immunotherapy and Immune Responses
  • Neuroinflammation and Neurodegeneration Mechanisms
  • Urticaria and Related Conditions
  • Allergic Rhinitis and Sensitization
  • Corneal Surgery and Treatments

Best Publications

  • See no evil, hear no evil, do no evil: The lessons of immune privilege

    Jerry Y Niederkorn

  • IL-17 disrupts corneal barrier following desiccating stress.

    C. S. De Paiva;S. Chotikavanich;S. B. Pangelinan;J. D. Pitcher

  • Immunosuppressive factors secreted by human amniotic epithelial cells.

    Haochuan Li;Jerry Y. Niederkorn;Sudha Neelam;Elizabeth Mayhew

  • Desiccating Stress Induces T Cell-Mediated Sjögren’s Syndrome-Like Lacrimal Keratoconjunctivitis

    Jerry Y. Niederkorn;Michael E. Stern;Stephen C. Pflugfelder;Cintia S. De Paiva

  • Dry Eye–Induced Conjunctival Epithelial Squamous Metaplasia Is Modulated by Interferon-γ

    Cintia S. De Paiva;Arturo L. Villarreal;Rosa M. Corrales;Hassan T. Rahman

  • A novel role for TGF-beta and IL-10 in the induction of immune privilege.

    Thomas J. D'Orazio;Jerry Y. Niederkorn

  • Induction of anterior chamber-associated immune deviation requires an intact, functional spleen

    J W Streilein;J Y Niederkorn

  • Immune privilege and immune regulation in the eye.

    Jerry Y. Niederkorn

  • Cutting Edge: Role of Macrophage Migration Inhibitory Factor in Inhibiting NK Cell Activity and Preserving Immune Privilege

    Rajendra Apte;D. Sinha;E. Mayhew;G. J. Wistow

  • The pathophysiology of Acanthamoeba keratitis.

    Daniel W. Clarke;Jerry Y. Niederkorn

  • Resistance of Acanthamoeba castellanii Cysts to Physical, Chemical, and Radiological Conditions

    A. Aksozek;K. McClellan;K. Howard;J. Y. Niederkorn

  • Deviant immune responses to allogeneic tumors injected intracamerally and subcutaneously in mice.

    J Niederkorn;J W Streilein;J A Shadduck

  • The pathogenesis of Acanthamoeba keratitis

    Jerry Y. Niederkorn;Hassan Alizadeh;Henry Leher;James P. McCulley

  • The immune privilege of corneal allografts.

    Jerry Y. Niederkorn

  • Systemic immune unresponsiveness induced in adult mice by anterior chamber presentation of minor histocompatibility antigens.

    J. W. Streilein;Jerry Y Niederkorn;J. A. Shadduck

  • Promotion of murine orthotopic corneal allograft survival by systemic administration of anti-CD4 monoclonal antibody.

    Yu-Guang He;J. Ross;Jerry Y Niederkorn

  • Immune privilege in the anterior chamber of the eye.

    Jerry Y. Niederkorn

  • PD-L1: PD-1 interaction contributes to the functional suppression of T-cell responses to human uveal melanoma cells in vitro.

    Wanhua Yang;Peter W. Chen;Haochuan Li;Hassan Alizadeh

  • Human uveal melanoma cells produce macrophage migration-inhibitory factor to prevent lysis by NK cells.

    Amanda C. Repp;Elizabeth S. Mayhew;Sherine Apte;Jerry Y. Niederkorn

  • Autoimmunity at the ocular surface: pathogenesis and regulation

    M E Stern;C S Schaumburg;R Dana;M Calonge

  • Immune mechanisms of corneal allograft rejection.

    Jerry Y. Niederkorn

  • The role of contact lenses, trauma, and Langerhans cells in a Chinese hamster model of Acanthamoeba keratitis

    F. Van Klink;H. Alizadeh;Yu-Guang He;J. A. Mellon

Frequent Co-Authors

Stephen C. Pflugfelder
Stephen C. Pflugfelder Baylor College of Medicine
Michael E. Stern
Michael E. Stern University of Cologne
J W Streilein
J W Streilein Harvard University
De-Quan Li
De-Quan Li Baylor College of Medicine
Reza Dana
Reza Dana Massachusetts Eye and Ear Infirmary
Martine J. Jager
Martine J. Jager Leiden University Medical Center
Peter Chen
Peter Chen ETH Zurich
Joseph Sambrook
Joseph Sambrook The University of Texas Southwestern Medical Center
Linda D. Hazlett
Linda D. Hazlett Wayne State University
Henry J. Kaplan
Henry J. Kaplan University of Louisville

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