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Molecular Biology

D-Index
86
Citations
379464
World Ranking
812
National Ranking
429

Overview

Joseph Sambrook was affiliated with The University of Texas Southwestern Medical Center in the United States. Their research centered primarily on biochemistry, genetics, and molecular biology, with substantial contributions to molecular biology techniques and applications as well as bacterial genetics and biotechnology.

The main fields of study encompassed by Sambrook included:

  • Biochemistry, Genetics and Molecular Biology

Within these fields, their work covered several subfields such as:

  • Molecular Biology
  • Genetics
  • Ecology
  • Biotechnology
  • Biomedical Engineering

The research topics Sambrook investigated reflected these fields and included:

  • RNA and protein synthesis mechanisms
  • DNA and Nucleic Acid Chemistry
  • Molecular Biology Techniques and Applications
  • Bacterial Genetics and Biotechnology
  • Bacteriophages and microbial interactions
  • Advanced biosensing and bioanalysis techniques
  • RNA modifications and cancer

Sambrook contributed extensively to published literature. A prominent venue for their work was Cold Spring Harbor Protocols, in which they published a significant number of papers, including the following recent examples:

  • Precipitation of RNA with Ethanol, 2020, Cold Spring Harbor Protocols
  • The Inoue Method for Preparation and Transformation of Competent Escherichia coli: "Ultracompetent" Cells, 2020, Cold Spring Harbor Protocols
  • Alkaline Phosphatase, 2020, Cold Spring Harbor Protocols
  • Cloning and Transformation with Plasmid Vectors, 2021, Cold Spring Harbor Protocols
  • Transformation of Escherichia coli by Electroporation, 2020, Cold Spring Harbor Protocols

Throughout their career, Sambrook collaborated frequently with several coauthors, most notably Michael R. Green.

Best Publications

  • Molecular Cloning: A Laboratory Manual

    Joseph Sambrook;E. F. Fritsch;Tom Maniatis

  • Molecular cloning–A laboratory manual. New York: Cold Spring Harbor Laboratory. 1982, 545 S., 42 $

    T. Mamiatis;E. F. Fritsch;J. Sambrook;J. Engel

  • Molecular Cloning: A Laboratory Manual Volume 3

    Michael R. Green;Joseph Sambrook

  • Molecular cloning : a laboratory manual

    Joseph Frank Sambrook;David William Russell

  • Protein folding in the cell.

    Mary-Jane Gething;Joseph Sambrook

  • Detection of two restriction endonuclease activities in Haemophilus parainfluenzae using analytical agarose--ethidium bromide electrophoresis

    Phillip A. Sharp;Bill Sugden;Joe Sambrook

  • The presence of malfolded proteins in the endoplasmic reticulum signals the induction of glucose-regulated proteins

    Yasunori Kozutsumi;Mark Segal;Karl Normington;Mary-Jane Gething

  • A transmembrane protein with a cdc2+/CDC28-related kinase activity is required for signaling from the ER to the nucleus.

    Kazutoshi Morl;Wenzhen Ma;Mary-Jane Gething;Joseph Sambrook

  • Purification of nucleic acids by extraction with phenol:chloroform.

    Joseph Sambrook;David W. Russell

  • Affinity panning of a library of peptides displayed on bacteriophages reveals the binding specificity of BiP.

    Sylvie Blond-Elguindi;Steven E. Cwirla;William J. Dower;Robert J. Lipshutz

  • The Condensed Protocols from Molecular Cloning: A Laboratory Manual

    David Russell;Joseph Sambrook;David W. Russell

  • Molecular Cloning A Laboratory Manual Fourth Edition

    Keith Roberts;Peter Walter;Michael Richard Green;Joseph Sambrook

  • The arrangement of simian virus 40 sequences in the DNA of transformed cells

    Michael Botchan;William Topp;Joe Sambrook

  • S. cerevisiae encodes an essential protein homologous in sequence and function to mammalian BiP

    Karl Normington;Kenji Kohno;Yasunori Kozutsumi;Mary-Jane Gething

  • A 22 bp cis-acting element is necessary and sufficient for the induction of the yeast KAR2 (BiP) gene by unfolded proteins.

    K Mori;A Sant;K Kohno;K Normington

  • Dominant Negative ATM Mutations in Breast Cancer Families

    Georgia Chenevix-Trench;Amanda B. Spurdle;Magtouf Gatei;Helena Kelly

  • The Integrated State of Viral DNA in SV40-Transformed Cells

    J. Sambrook;H. Westphal;P. R. Srinivasan;R. Dulbecco

  • The involvement of calcium in transport of secretory proteins from the endoplasmic reticulum

    Joseph F. Sambrook

  • The promoter region of the yeast KAR2 (BiP) gene contains a regulatory domain that responds to the presence of unfolded proteins in the endoplasmic reticulum

    K Kohno;K Normington;J Sambrook;M J Gething

  • Cell-surface expression of influenza haemagglutinin from a cloned DNA copy of the RNA gene.

    Mary-Jane Gething;Joe Sambrook

Frequent Co-Authors

David W. Russell
David W. Russell University of Washington
Robert D. Gerard
Robert D. Gerard The University of Texas Southwestern Medical Center
Michael R. Botchan
Michael R. Botchan University of California, Berkeley
Bill Sugden
Bill Sugden University of Wisconsin–Madison
Ulf Pettersson
Ulf Pettersson Uppsala University
Elizabeth J. Goldsmith
Elizabeth J. Goldsmith The University of Texas Southwestern Medical Center
Georgia Chenevix-Trench
Georgia Chenevix-Trench QIMR Berghofer Medical Research Institute
Kim Orth
Kim Orth The University of Texas Southwestern Medical Center
Jerry Y. Niederkorn
Jerry Y. Niederkorn The University of Texas Southwestern Medical Center

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