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Microbiology

D-Index
59
Citations
9212
World Ranking
3341
National Ranking
1317

Overview

Linda D. Hazlett is affiliated with Wayne State University in the United States and has contributed significantly to research in multiple scientific domains, particularly biochemistry, genetics, molecular biology, environmental science, and medicine. Their work spans various subfields including health, toxicology, mutagenesis, molecular biology, immunology, pharmacology, and radiology, nuclear medicine and imaging.

The scientist's research topics frequently address areas such as air quality and health impacts, climate change and health impacts, immune response and inflammation, corneal surgery and treatments, pharmacological effects of natural compounds, advanced glycation end products research, and ocular surface and contact lens studies.

Recent publications by Linda D. Hazlett include the following:

  • Airborne Particulates Affect Corneal Homeostasis and Immunity (2020) in Investigative Ophthalmology & Visual Science
  • Phenotypes of CF rabbits generated by CRISPR/Cas9-mediated disruption of the CFTR gene (2020) in JCI Insight
  • Nano-Biomaterials for Retinal Regeneration (2021) in Nanomaterials
  • Effects of Glycyrrhizin Treatment on Diabetic Cornea (2020) in Journal of Ocular Pharmacology and Therapeutics
  • Targeting Inflammation Driven by HMGB1 in Bacterial Keratitis-A Review (2021) in Pathogens

Linda D. Hazlett has published frequently in the following venues:

  • Pathogens
  • The Ocular Surface
  • Investigative Ophthalmology & Visual Science
  • International Journal of Molecular Sciences
  • Scientific Reports

Frequent co-authors who have collaborated with Linda D. Hazlett include:

  • Sharon A. McClellan
  • Mallika Somayajulu
  • Ahalya Pitchaikannu
  • Shunbin Xu
  • Denise Bessert

Best Publications

  • Corneal response to Pseudomonas aeruginosa infection.

    Linda Dondero Hazlett

  • Defensins in innate immunity

    Linda Hazlett;Minhao Wu

  • Thymosin Beta 4 Promotes Corneal Wound Healing and Decreases Inflammation in Vivo Following Alkali Injury

    Gabriel Sosne;Elizabeth A. Szliter;Ronald Barrett;Karen A. Kernacki

  • Prolonged Elevation of IL-1 in Pseudomonas aeruginosa Ocular Infection Regulates Macrophage-Inflammatory Protein-2 Production, Polymorphonuclear Neutrophil Persistence, and Corneal Perforation

    Xiaowen L. Rudner;Karen A. Kernacki;Ronald P. Barrett;Linda D. Hazlett

  • Increased severity of Pseudomonas aeruginosa corneal infection in strains of mice designated as Th1 versus Th2 responsive

    Linda D. Hazlett;Sharon McClellan;Byungsuk Kwon;Ronald Barrett

  • Macrophage inflammatory protein-2 is a mediator of polymorphonuclear neutrophil influx in ocular bacterial infection.

    Karen A. Kernacki;Ronald P. Barrett;Jeffery A. Hobden;Linda D. Hazlett

  • Thymosin beta 4 promotes corneal wound healing and modulates inflammatory mediators in vivo.

    Gabriel Sosne;Chi Chao Chan;Khoan Thai;Michael Kennedy

  • Evidence for N-acetylmannosamine as an ocular receptor for P. aeruginosa adherence to scarified cornea.

    L D Hazlett;M M Moon;M Strejc;R S Berk

  • Pili and lipopolysaccharide of Pseudomonas aeruginosa bind to the glycolipid asialo GM1.

    S K Gupta;R S Berk;S Masinick;L D Hazlett

  • Pseudomonas aeruginosa lipopolysaccharide binds galectin-3 and other human corneal epithelial proteins.

    Suresh K. Gupta;Sharon Masinick;Michael Garrett;Linda D. Hazlett

  • Early cytokine and chemokine gene expression during Pseudomonas aeruginosa corneal infection in mice

    Karen A. Kernacki;Dennis J. Goebel;Michael S. Poosch;Linda D. Hazlett

  • IL-33 Shifts Macrophage Polarization, Promoting Resistance against Pseudomonas aeruginosa Keratitis

    Linda D. Hazlett;Sharon A. McClellan;Ronald P. Barrett;Xi Huang

  • Silencing Toll-like receptor-9 in Pseudomonas aeruginosa keratitis.

    Xi Huang;Ronald P. Barrett;Sharon A. McClellan;Linda D. Hazlett

  • TLR4 Is Required for Host Resistance in Pseudomonas aeruginosa Keratitis

    Xi Huang;Wenjin Du;Sharon A. McClellan;Ronald P. Barrett

  • Macrophages Restrict Pseudomonas aeruginosa Growth, Regulate Polymorphonuclear Neutrophil Influx, and Balance Pro- and Anti-Inflammatory Cytokines in BALB/c Mice

    Sharon A. McClellan;Xi Huang;Ronald P. Barrett;Nico van Rooijen

  • SIGIRR promotes resistance against Pseudomonas aeruginosa keratitis by down-regulating type-1 immunity and IL-1R1 and TLR4 signaling.

    Xi Huang;Linda D. Hazlett;Wenjin Du;Ronald P. Barrett

  • In vivo bacterial protease production during Pseudomonas aeruginosa corneal infection.

    K A Kernacki;J A Hobden;L D Hazlett;R Fridman

  • Pathogenic Mechanisms of P. aeruginosa Keratitis: A Review of the Role of T Cells, Langerhans Cells, PMN, and Cytokines

    Linda D. Hazlett

  • Toll-like receptors and the eye.

    Fu Shin X Yu;Linda D. Hazlett

  • Infectious corneal ulceration: a proposal for neglected tropical disease status.

    Lawson Ung;Nisha R. Acharya;Tushar Agarwal;Eduardo C. Alfonso

  • TREM-1 Amplifies Corneal Inflammation after Pseudomonas aeruginosa Infection by Modulating Toll-Like Receptor Signaling and Th1/Th2-Type Immune Responses

    Minhao Wu;Anping Peng;Mingxia Sun;Qiuchan Deng

Frequent Co-Authors

Fu-Shin X. Yu
Fu-Shin X. Yu Wayne State University
Michael E. Stern
Michael E. Stern University of Cologne
Hynda K. Kleinman
Hynda K. Kleinman George Washington University
Reza Dana
Reza Dana Massachusetts Eye and Ear Infirmary
Eric Pearlman
Eric Pearlman University of California, Irvine
Jerry Y. Niederkorn
Jerry Y. Niederkorn The University of Texas Southwestern Medical Center
Alan R. Burns
Alan R. Burns University of Houston
Rafael Fridman
Rafael Fridman Wayne State University
Daniel B. Jones
Daniel B. Jones Beth Israel Deaconess Medical Center
Mark D. P. Willcox
Mark D. P. Willcox University of New South Wales

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