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D-Index & Metrics

Biology and Biochemistry

D-Index
51
Citations
7064
World Ranking
17358
National Ranking
7132

Overview

Fu-Shin X. Yu is affiliated with Wayne State University in the United States and has contributed extensively to the fields of medicine and biochemistry, genetics, and molecular biology. Their research spans several subfields including molecular biology, ophthalmology, immunology, public health, environmental and occupational health, and radiology, nuclear medicine, and imaging.

The scientist's work primarily revolves around ocular biology and immunology, focusing on topics such as ocular surface and contact lenses, corneal surgery and treatments, ocular infections and treatments, advanced glycation end products research, psoriasis treatment and pathogenesis, neutrophil, myeloperoxidase and oxidative mechanisms, and immune response and inflammation.

Frequent collaboration is a notable aspect of their research output. Collaborators include Nan Gao, Rao Me, Chenyang Dai, Patrick Lee, and Yangyang Zhang, with whom they have published numerous papers.

Fu-Shin X. Yu has published in several scientific journals, often contributing to these venues multiple times:

  • Investigative Ophthalmology & Visual Science (4 publications)
  • Pain (2 publications)
  • Diabetes (1 publication)
  • Journal of Drug Targeting (1 publication)
  • The Journal of Immunology (1 publication)

Some recent research papers authored or co-authored by Fu-Shin X. Yu are:

  • Role of VIP and Sonic Hedgehog Signaling Pathways in Mediating Epithelial Wound Healing, Sensory Nerve Regeneration, and Their Defects in Diabetic Corneas, 2020, published in Diabetes
  • Lipo-PEG nano-ocular formulation successfully encapsulates hydrophilic fluconazole and traverses corneal and non-corneal path to reach posterior eye segment, 2021, published in Journal of Drug Targeting
  • ISG15 Acts as a Mediator of Innate Immune Response to Pseudomonas aeruginosa Infection in C57BL/6J Mouse Corneas, 2020, published in Investigative Ophthalmology & Visual Science
  • Role of IL-36γ/IL-36R Signaling in Corneal Innate Defense Against Candida albicans Keratitis, 2021, published in Investigative Ophthalmology & Visual Science
  • IL-36α Enhances Host Defense against Pseudomonas aeruginosa Keratitis in C57BL/6 Mouse Corneas, 2021, published in The Journal of Immunology

Best Publications

  • Toll-like receptor 5-mediated corneal epithelial inflammatory responses to Pseudomonas aeruginosa flagellin.

    Jing Zhang;Keping Xu;Balamurali Ambati;Fu Shin X Yu

  • Corneal epithelial tight junctions and their response to lipopolysaccharide challenge.

    Xian-jin Yi;Yuan Wang;Fu-Shin X. Yu

  • Growth factors and corneal epithelial wound healing

    Fu Shin X Yu;Jia Yin;Keping Xu;Jenny Huang

  • Toll-like receptor 3 agonist poly(I: C)-induced antiviral response in human corneal epithelial cells

    Ashok Kumar;Jing Zhang;Fu Shin X Yu

  • Wound-induced ATP release and EGF receptor activation in epithelial cells.

    Jia Yin;Keping Xu;Jing Zhang;Ashok Kumar

  • Wound-Induced HB-EGF Ectodomain Shedding and EGFR Activation in Corneal Epithelial Cells

    Ke Ping Xu;Yu Ding;Jianhua Ling;Zheng Dong

  • Toll-like receptor 2-mediated expression of β-defensin-2 in human corneal epithelial cells

    Ashok Kumar;Jing Zhang;Fu Shin X Yu

  • Herpes simplex virus 1 infection induces the expression of proinflammatory cytokines, interferons and TLR7 in human corneal epithelial cells.

    Hui Li;Jing Zhang;Ashok Kumar;Mei Zheng

  • High Glucose Suppresses Epidermal Growth Factor Receptor/Phosphatidylinositol 3-Kinase/Akt Signaling Pathway and Attenuates Corneal Epithelial Wound Healing

    Ke Ping Xu;Yanfeng Li;Alexander V. Ljubimov;Fu Shin X Yu

  • Activation of ERK1/2 MAP kinase pathway induces tight junction disruption in human corneal epithelial cells.

    Yuan Wang;Jing Zhang;Xian-jin Yi;Fu-Shin X. Yu

  • Innate immune response of corneal epithelial cells to Staphylococcus aureus infection: role of peptidoglycan in stimulating proinflammatory cytokine secretion.

    Ashok Kumar;Jing Zhang;Fu Shin X Yu

  • Toll-Like Receptors and Corneal Innate Immunity

    Ashok Kumar;Fu Shin X Yu

  • Impaired Epithelial Wound Healing and EGFR Signaling Pathways in the Corneas of Diabetic Rats

    Keping Xu;Fu-Shin X. Yu

  • Cathelicidin-related antimicrobial peptide is required for effective lung mucosal immunity in Gram-negative bacterial pneumonia.

    Melissa A. Kovach;Megan N. Ballinger;Michael W. Newstead;Xianying Zeng

  • Apoptosis-Resistance of Hypoxic Cells: Multiple Factors Involved and a Role for IAP-2

    Zheng Dong;Jin Zhao Wang;Fushin Yu;Manjeri A. Venkatachalam

  • Flagellin Stimulates Protective Lung Mucosal Immunity: Role of Cathelicidin-Related Antimicrobial Peptide

    Fu Shin Yu;Matthew D. Cornicelli;Melissa A. Kovach;Michael W. Newstead

  • Cross talk between c-Met and epidermal growth factor receptor during retinal pigment epithelial wound healing.

    Ke-Ping Xu;Fu-Shin X. Yu

  • Metformin suppresses retinal angiogenesis and inflammation in vitro and in vivo.

    Jing Han;Yue Li;Xiuli Liu;Tongrong Zhou

  • Corneal Organ Culture Model for Assessing Epithelial Responses to Surfactants

    Ke-Ping Xu;Xin-Fang Li;Fu-Shin X. Yu

  • Dendritic cell dysfunction and diabetic sensory neuropathy in the cornea

    Nan Gao;Chenxi Yan;Patrick Lee;Haijing Sun

Frequent Co-Authors

Theodore J. Standiford
Theodore J. Standiford University of Michigan–Ann Arbor
Qing Sheng Mi
Qing Sheng Mi Henry Ford Health System
Zheng Dong
Zheng Dong Augusta University
Richard L. Gallo
Richard L. Gallo University of California, San Diego
Linda D. Hazlett
Linda D. Hazlett Wayne State University
Gary W. Abrams
Gary W. Abrams Wayne State University
Alexander V. Ljubimov
Alexander V. Ljubimov Cedars-Sinai Medical Center
Maria G. Castro
Maria G. Castro University of Michigan–Ann Arbor
Jian-Fang Gui
Jian-Fang Gui Chinese Academy of Sciences
Michael Dean
Michael Dean National Institutes of Health

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