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Chemistry

D-Index
72
Citations
15403
World Ranking
5381
National Ranking
311

Biology and Biochemistry

D-Index
75
Citations
16625
World Ranking
5425
National Ranking
418

Overview

Shamshad Cockcroft is affiliated with University College London in the United Kingdom and has contributed extensively to the fields of Biochemistry, Genetics and Molecular Biology, and Medicine. Their research spans several subfields, including Molecular Biology, Cell Biology, Surgery, Physiology, and Biochemistry. The main topics addressed in their work include Cellular transport and secretion, Pancreatic function and diabetes, Protein Kinase Regulation and GTPase Signaling, Inflammasome and immune disorders, Sphingolipid Metabolism and Signaling, Cholesterol and Lipid Metabolism, and Endoplasmic Reticulum Stress and Disease.

Shamshad Cockcroft has published papers in various scientific venues. Frequent publication venues include Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids, bioRxiv (Cold Spring Harbor Laboratory), Essays in Biochemistry, Frontiers in Cell and Developmental Biology, and Progress in Lipid Research.

Recent papers from Cockcroft provide insight into their diverse research interests:

  • Phosphatidylinositol(4,5)bisphosphate: diverse functions at the plasma membrane, 2020, Essays in Biochemistry
  • CDP-Diacylglycerol Synthases (CDS): Gateway to Phosphatidylinositol and Cardiolipin Synthesis, 2020, Frontiers in Cell and Developmental Biology
  • Phospholipase C families: Common themes and versatility in physiology and pathology, 2020, Progress in Lipid Research
  • Fatty acid synthesis promotes inflammasome activation through NLRP3 palmitoylation, 2024, Cell Reports
  • Courier service for phosphatidylinositol: PITPs deliver on demand, 2021, Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids

Collaboration has been a consistent aspect of Cockcroft's career, with frequent co-authors including Stuart Leishman, Paras Anand, Matilda Katan, Nicholas J. Blunsom, and Jacques Behmoaras. These partnerships highlight interdisciplinary approaches within their research domains.

Best Publications

  • Role of guanine nucleotide binding protein in the activation of polyphosphoinositide phosphodiesterase.

    Shamshad Cockcroft;Bastien D. Gomperts

  • Phospholipase D: a downstream effector of ARF in granulocytes

    Shamshad Cockcroft;Geraint M. H. Thomas;Amanda Fensome;Blandine Geny

  • Inositol-lipid-specific phospholipase C isoenzymes and their differential regulation by receptors.

    S Cockcroft;G M H Thomas

  • Polyphosphoinositide phosphodiesterase: regulation by a novel guanine nucleotide binding protein, Gp

    Shamshad Cockcroft

  • Two roles for guanine nucleotides in the stimulus-secretion sequence of neutrophils.

    M. M. Barrowman;S. Cockcroft;B. D. Gomperts

  • Stimulated neutrophils from patients with autosomal recessive chronic granulomatous disease fail to phosphorylate a Mr-44,000 protein.

    Anthony W. Segal;Paul G. Heyworth;Shamshad Cockcroft;Margaret M. Barrowman

  • Characterization of p150, an Adaptor Protein for the Human Phosphatidylinositol (PtdIns) 3-Kinase: SUBSTRATE PRESENTATION BY PHOSPHATIDYLINOSITOL TRANSFER PROTEIN TO THE p150·;PtdIns 3-KINASE COMPLEX *

    Christina Panaretou;Jan Domin;Shamshad Cockcroft;Michael D. Waterfield

  • ATP induces nucleotide permeability in rat mast cells

    S Cockcroft;B D Gomperts

  • THE ATP4- RECEPTOR OF RAT MAST-CELLS

    S Cockcroft;B D Gomperts

  • A new family of StART domain proteins at membrane contact sites has a role in ER-PM sterol transport

    Alberto T Gatta;Louise H Wong;Yves Y Sere;Diana M Calderón-Noreña

  • Type I phosphatidylinositol 4-phosphate 5-kinase directly interacts with ADP-ribosylation factor 1 and is responsible for phosphatidylinositol 4,5-bisphosphate synthesis in the golgi compartment.

    David H. Jones;James B. Morris;Clive P. Morgan;Hisatake Kondo

  • An essential role for phosphatidylinositol transfer protein in phospholipase C-Mediated inositol lipid signaling

    Geraint M.H. Thomas;Emer Cunningham;Amanda Fensome;Andrew Ball

  • Two G-proteins act in series to control stimulus-secretion coupling in mast cells: use of neomycin to distinguish between G-proteins controlling polyphosphoinositide phosphodiesterase and exocytosis.

    Shamshad Cockcroft;Tim W. Howell;Bastien D. Gomperts

  • Signalling roles of mammalian phospholipase D1 and D2.

    S Cockcroft

  • Essential synergy between Ca2+ and guanine nucleotides in exocytotic secretion from permeabilized rat mast cells.

    Tim W. Howell;Shamshad Cockcroft;Bastien D. Gomperts

  • Regulation of inositol lipid-specific phospholipase cdelta by changes in Ca2+ ion concentrations.

    Victoria Allen;Philip Swigart;Robert Cheung;Shamshad Cockcroft

  • Requirement for phosphatidylinositol transfer protein in epidermal growth factor signaling

    Andrea Kauffmann-Zeh;Geraint M. H. Thomas;Andrew Ball;Simon Prosser

  • Membrane targeting and activation of the Lowe syndrome protein OCRL1 by rab GTPases.

    Noora Hyvola;Aipo Diao;Eddie McKenzie;Alison Skippen

  • Phospholipase D and membrane traffic. Potential roles in regulated exocytosis, membrane delivery and vesicle budding.

    David Jones;Clive Morgan;Shamshad Cockcroft

  • ARF and PITP restore GTPγS-stimulated protein secretion from cytosol-depleted HL60 cells by promoting PIP2 synthesis

    Amanda Fensome;Emer Cunningham;Simon Prosser;Siow Khoon Tan

Frequent Co-Authors

David T. Jones
David T. Jones University College London
J. Justin Hsuan
J. Justin Hsuan University College London
Neil Q. McDonald
Neil Q. McDonald The Francis Crick Institute
Matilda Katan
Matilda Katan University College London
Robert H. Insall
Robert H. Insall University of Glasgow
Timothy P. Levine
Timothy P. Levine University College London
Anant K. Menon
Anant K. Menon Cornell University
Nicholas T. Ktistakis
Nicholas T. Ktistakis Babraham Institute
Pentti Somerharju
Pentti Somerharju University of Helsinki
Nicholas F. Totty
Nicholas F. Totty Ludwig Cancer Research

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