Anton J.G. Horrevoets

Best Publications

• Atheroprotective communication between endothelial cells and smooth muscle cells through miRNAs.

  Eduard Hergenreider;Susanne Heydt;Karine Tréguer;Thomas Boettger

  1473
  Citations

• Prolonged fluid shear stress induces a distinct set of endothelial cell genes, most specifically lung Krüppel-like factor (KLF2).

  Rob J. Dekker;Simone van Soest;Simone van Soest;Ruud D. Fontijn;Ruud D. Fontijn;Sonia Salamanca;Sonia Salamanca

  830
  Citations

• Endothelial KLF2 Links Local Arterial Shear Stress Levels to the Expression of Vascular Tone-Regulating Genes

  Rob J. Dekker;Johannes V. van Thienen;Jakub Rohlena;Saskia C. de Jager

  452
  Citations

• KLF2 provokes a gene expression pattern that establishes functional quiescent differentiation of the endothelium

  Rob J. Dekker;Reinier A. Boon;Mariska G. Rondaij;Astrid Kragt

  436
  Citations

• Monocyte subset accumulation in the human heart following acute myocardial infarction and the role of the spleen as monocyte reservoir

  Anja M. van der Laan;Ellis N. ter Horst;Ronak Delewi;Mark P.V. Begieneman

  267
  Citations

• Vascular endothelial genes that are responsive to tumor necrosis factor-alpha in vitro are expressed in atherosclerotic lesions, including inhibitor of apoptosis protein-1, stannin, and two novel genes.

  A. J. G. Horrevoets;R. D. Fontijn;A. J. Van Zonneveld;C. J. M. De Vries

  237
  Citations

• Key transcriptional regulators of the vasoprotective effects of shear stress

  Unknown

  231
  Citations

• Primary cilia sensitize endothelial cells for fluid shear stress.

  Beerend P. Hierck;Kim Van der Heiden;Fanneke E. Alkemade;Simone Van de Pas

  222
  Citations

• KLF2 Primes the Antioxidant Transcription Factor Nrf2 for Activation in Endothelial Cells

  Joost O. Fledderus;Reinier A. Boon;Oscar L. Volger;Hanna Hurttila

  219
  Citations

• Prolonged shear stress and KLF2 suppress constitutive proinflammatory transcription through inhibition of ATF2

  Joost O. Fledderus;Johannes V. Van Thienen;Reinier A. Boon;Rob J. Dekker

  195
  Citations

• The apolipoprotein L gene cluster has emerged recently in evolution and is expressed in human vascular tissue.

  Houshang Monajemi;Ruud D. Fontijn;Hans Pannekoek;Anton J.G. Horrevoets

  187
  Citations

• Nrf2-dependent and -independent responses to nitro-fatty acids in human endothelial cells: Identification of heat shock response as the major pathway activated by nitro-oleic acid

  Emilia Kansanen;Henna-Kaisa Jyrkkänen;Oscar L. Volger;Hanna Leinonen

  180
  Citations

• The human kinesin-like protein RB6K is under tight cell cycle control and is essential for cytokinesis.

  Ruud D. Fontijn;Bruno Goud;Arnaud Echard;Florence Jollivet

  176
  Citations

• Shear stress sustains atheroprotective endothelial KLF2 expression more potently than statins through mRNA stabilization

  Johannes V van Thienen;Joost O Fledderus;Rob J Dekker;Jakub Rohlena

  175
  Citations

• Comparative proteomics of human endothelial cell caveolae and rafts using two-dimensional gel electrophoresis and mass spectrometry

  Richard R. Sprenger;Dave Speijer;Jaap Willem Back;Chris G. de Koster

  161
  Citations

• P-Selectin Glycoprotein Ligand-1 Is Expressed on Endothelial Cells and Mediates Monocyte Adhesion to Activated Endothelium

  Paula Da Costa Martins;Juan Jesús García-Vallejo;Johannes V. Van Thienen;Mar Fernandez-Borja

  157
  Citations

• Simvastatin has an anti-inflammatory effect on macrophages via upregulation of an atheroprotective transcription factor, Kruppel-like factor 2

  Tiina T. Tuomisto;Henri Lumivuori;Emilia Kansanen;Sanna-Kaisa Häkkinen

  146
  Citations

• MicroRNAs regulate human brain endothelial cell barrier function in inflammation: implications for multiple sclerosis

  Arie Reijerkerk;M. Alejandro Lopez-Ramirez;Bert van het Hof;Joost A.R. Drexhage

  144
  Citations

• Expression of a retinoic acid signature in circulating CD34 cells from coronary artery disease patients.

  Tineke C T M van der Pouw Kraan;Stephan H Schirmer;Stephan H Schirmer;Joost O Fledderus;Perry D Moerland

  8
  Citations

• KLF2 provokes a gene expression pattern that establishes functional quiescent differentiation of the endothelium

  Reinier A. Boon;Rob J. Dekker;Mariska G. Rondaij;Oscar L. Volger

  1
  Citations