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Biology and Biochemistry

D-Index
68
Citations
26988
World Ranking
7630
National Ranking
3471

Overview

Averil Ma is affiliated with the University of California, San Francisco in the United States. Their research primarily spans the fields of medicine, biochemistry, genetics, and molecular biology, with significant contributions also in immunology and microbiology.

The scientist's work covers several subfields of study, including immunology, molecular biology, cancer research, biomedical engineering, and oncology. The main topics they focus on include NF-κB signaling pathways, immune response and inflammation, gut microbiota and health, Clostridium difficile and Clostridium perfringens research, nanoplatforms for cancer theranostics, immune cells in cancer, and mechanisms and regulation of cell death.

Averil Ma has published extensively in various venues, with the most frequent publication platforms being bioRxiv (Cold Spring Harbor Laboratory), Gastroenterology, Scientific Reports, Nature Immunology, and the Journal of Clinical Investigation.

Some recent notable papers by Averil Ma are as follows:

  • Adaptive response to inflammation contributes to sustained myelopoiesis and confers a competitive advantage in myelodysplastic syndrome HSCs (2020, Nature Immunology)
  • Non-catalytic ubiquitin binding by A20 prevents psoriatic arthritis-like disease and inflammation (2020, Nature Immunology)
  • Strain-resolved analysis in a randomized trial of antibiotic pretreatment and maintenance dose delivery mode with fecal microbiota transplant for ulcerative colitis (2022, Scientific Reports)
  • Distinct phases of adult microglia proliferation: a Myc-mediated early phase and a Tnfaip3-mediated late phase (2022, Cell Discovery)
  • Microbial signals, MyD88, and lymphotoxin drive TNF-independent intestinal epithelial tissue damage (2022, Journal of Clinical Investigation)

Averil Ma frequently collaborates with a number of coauthors, including Barbara A. Malynn, Bahram Razani, Rommel Advincula, Philip Achacoso, and Xiaofei Sun.

Best Publications

  • De-ubiquitination and ubiquitin ligase domains of A20 downregulate NF-κB signalling

    Ingrid E. Wertz;Karen M. O'Rourke;Honglin Zhou;Michael Eby

  • IL-15 receptor maintains lymphoid homeostasis by supporting lymphocyte homing and proliferation

    James P Lodolce;David L Boone;Sophia Chai;Rachel E Swain

  • The combined functions of proapoptotic Bcl-2 family members bak and bax are essential for normal development of multiple tissues.

    Tullia Lindsten;Andrea J. Ross;Ayala King;Wei Xing Zong

  • Failure to Regulate TNF-Induced NF-κB and Cell Death Responses in A20-Deficient Mice

    Eric G. Lee;David L. Boone;Sophia Chai;Shon L. Libby

  • The ubiquitin-modifying enzyme A20 is required for termination of Toll-like receptor responses.

    David L. Boone;Emre E. Turer;Eric G. Lee;Regina Celeste Ahmad

  • Interleukin 15 Is Required for Proliferative Renewal of Virus-specific Memory CD8 T Cells

    Todd C. Becker;E. John Wherry;David Boone;Kaja Murali-Krishna

  • DIVERSE FUNCTIONS OF IL-2, IL-15, AND IL-7 IN LYMPHOID HOMEOSTASIS

    Averil Ma;Rima Koka;Patrick Burkett

  • Cytokines and autoimmunity

    John J O'Shea;Averil Ma;Peter Lipsky

  • Inhibition of NF-κB Signaling by A20 Through Disruption of Ubiquitin Enzyme Complexes

    Noula Shembade;Averil Ma;Edward W. Harhaj

  • A20: linking a complex regulator of ubiquitylation to immunity and human disease

    Averil Ma;Barbara A. Malynn

  • Multiple polymorphisms in the TNFAIP3 region are independently associated with systemic lupus erythematosus

    Stacy L. Musone;Kimberly E. Taylor;Timothy T. Lu;Joanne Nititham

  • Coordinate Expression and Trans Presentation of Interleukin (IL)-15Rα and IL-15 Supports Natural Killer Cell and Memory CD8+ T Cell Homeostasis

    Patrick R. Burkett;Rima Koka;Marcia Chien;Sophia Chai

  • GATA-1 and erythropoietin cooperate to promote erythroid cell survival by regulating bcl-xL expression.

    Todd Gregory;Channing Yu;Averil Ma;Stuart H. Orkin

  • IL-15Rα chaperones IL-15 to stable dendritic cell membrane complexes that activate NK cells via trans presentation

    Erwan Mortier;Tammy Woo;Rommel Advincula;Sara Gozalo

  • A Metabolite-Triggered Tuft Cell-ILC2 Circuit Drives Small Intestinal Remodeling

    Christoph Schneider;Claire E. O’Leary;Jakob von Moltke;Hong-Erh Liang

  • The Ubiquitin-Editing Enzyme A20 Restricts Nucleotide-Binding Oligomerization Domain Containing 2-Triggered Signals

    Osamu Hitotsumatsu;Regina Celeste Ahmad;Rita Tavares;Min Wang

  • A bacterial E3 ubiquitin ligase IpaH9.8 targets NEMO/IKK|[gamma]| to dampen the host NF-|[kappa]|B-mediated inflammatory response

    Hiroshi Ashida;Minsoo Kim;Marc Schmidt-Supprian;Averil Ma

  • Homeostatic MyD88-dependent signals cause lethal inflamMation in the absence of A20

    Emre E. Turer;Rita M. Tavares;Rita M. Tavares;Erwan Mortier;Osamu Hitotsumatsu

  • Interleukin (IL)-15Rα–deficient Natural Killer Cells Survive in Normal but Not IL-15Rα–deficient Mice

    Rima Koka;Patrick R. Burkett;Marcia Chien;Sophia Chai

  • A20 restricts ubiquitination of pro-interleukin-1β protein complexes and suppresses NLRP3 inflammasome activity

    Bao H. Duong;Michio Onizawa;Juan A. Oses-Prieto;Rommel Advincula

Frequent Co-Authors

Susan V. Lynch
Susan V. Lynch University of California, San Francisco
Lindsey A. Criswell
Lindsey A. Criswell National Institutes of Health
Sarah L. Gaffen
Sarah L. Gaffen University of Pittsburgh
Eugene B. Chang
Eugene B. Chang University of Chicago
Mark W. Musch
Mark W. Musch University of Chicago
Alma L. Burlingame
Alma L. Burlingame University of California, San Francisco
Elizabeth M. McNally
Elizabeth M. McNally Northwestern University
Hao Wu
Hao Wu Harvard University
Jianjun Liu
Jianjun Liu Genome Institute of Singapore
Tejal A. Desai
Tejal A. Desai University of California, San Francisco

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