World's Best Scientists 2026 revealed!

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Biology and Biochemistry

D-Index
91
Citations
28064
World Ranking
2334
National Ranking
1247

Medicine

D-Index
91
Citations
28020
World Ranking
11832
National Ranking
6067

Overview

Raj K. Puri is affiliated with the US Food and Drug Administration in the United States. Their research spans multiple fields of study, mainly focusing on Medicine, Biochemistry, Genetics and Molecular Biology, and Engineering. Within these fields, Puri's work is notably concentrated in several subfields including Oncology, Biomedical Engineering, Immunology, Molecular Biology, and Genetics.

The primary topics addressed in Puri's research include CAR-T cell therapy research, Toxin Mechanisms and Immunotoxins, Nanowire Synthesis and Applications, Viral Infectious Diseases and Gene Expression in Insects, Virus-based gene therapy research, Nanofabrication and Lithography Techniques, and Transgenic Plants and Applications.

Recent published papers reflect this breadth of research:

  • Identification and characterisation of novel CAR-T cells to target IL13Rα2 positive human glioma in vitro and in vivo, 2024, Clinical and Translational Medicine
  • Characterization of chimeric antigen receptor modified T cells expressing scFv-IL-13Rα2 after radiolabeling with 89Zirconium oxine for PET imaging, 2023, Journal of Translational Medicine
  • Recent Advances in IL-13Rα2-Directed Cancer Immunotherapy, 2022, Frontiers in Immunology
  • Clinical Development of Gene Therapies: The First Three Decades and Counting, 2020, Molecular Therapy - Methods & Clinical Development
  • A Novel Role of Interleukin 13 Receptor alpha2 in Perineural Invasion and its Association with Poor Prognosis of Patients with Pancreatic Ductal Adenocarcinoma, 2020, Cancers

Puri's frequent coauthors include Bharat Joshi with whom they have collaborated on nine occasions, Pamela Leland and Steven R. Bauer with five joint publications each, Dhiraj Kumar with three, and SuJin Hwang with two.

The scientist's work is regularly published in a number of scholarly venues. Among these, the most frequent publication venues are the Journal of Translational Medicine, Frontiers in Immunology, Molecular Therapy - Methods & Clinical Development, Cancers, and Clinical and Translational Medicine.

Best Publications

  • The MicroArray Quality Control (MAQC) project shows inter- and intraplatform reproducibility of gene expression measurements

    Leming Shi;Laura H. Reid;Wendell D. Jones;Richard Shippy

  • IL-13 signaling through the IL-13alpha2 receptor is involved in induction of TGF-beta1 production and fibrosis.

    Stefan Fichtner-Feigl;Warren Strober;Koji Kawakami;Raj K Puri

  • The Microarray Quality Control (MAQC)-II study of common practices for the development and validation of microarray-based predictive models

    Leming Shi;Gregory Campbell;Wendell D. Jones;Fabien Campagne

  • Gene expression in human embryonic stem cell lines: unique molecular signature

    Bhaskar Bhattacharya;Takumi Miura;Ralph Brandenberger;Josef Mejido

  • Phase III randomized trial of CED of IL13-PE38QQR vs Gliadel wafers for recurrent glioblastoma.

    Sandeep Kunwar;Susan Chang;Manfred Westphal;Michael Vogelbaum

  • MSC-based product characterization for clinical trials: an FDA perspective

    Michael Mendicino;Michael Mendicino;Alexander M. Bailey;Keith Wonnacott;Raj K. Puri

  • Receptor for Interleukin 13: INTERACTION WITH INTERLEUKIN 4 BY A MECHANISM THAT DOES NOT INVOLVE THE COMMON γ CHAIN SHARED BY RECEPTORS FOR INTERLEUKINS 2, 4, 7, 9, AND 15

    Nicholas I. Obiri;Waldemar Debinski;Warren J. Leonard;Raj K. Puri

  • The balance of reproducibility, sensitivity, and specificity of lists of differentially expressed genes in microarray studies

    Leming Shi;Wendell D. Jones;Roderick V. Jensen;Stephen C. Harris

  • The External RNA Controls Consortium: a progress report.

    Shawn C Baker;Steven R Bauer;Richard P Beyer;James D Brenton

  • cDNA Cloning and Characterization of the Human Interleukin 13 Receptor α Chain

    M. Javad Aman;Nahid Tayebi;Nicholas I. Obiri;Raj K. Puri

  • Direct intracerebral delivery of cintredekin besudotox (IL13-PE38QQR) in recurrent malignant glioma: a report by the Cintredekin Besudotox Intraparenchymal Study Group.

    Sandeep Kunwar;Michael D. Prados;Susan M. Chang;Mitchel S. Berger

  • A Novel Chimeric Protein Composed of Interleukin 13 and Pseudomonas Exotoxin Is Highly Cytotoxic to Human Carcinoma Cells Expressing Receptors for Interleukin 13 and Interleukin 4

    Waldemar Debinski;Nicholas I. Obiri;Ira Pastan;Raj K. Puri

  • Human glioma cells overexpress receptors for interleukin 13 and are extremely sensitive to a novel chimeric protein composed of interleukin 13 and pseudomonas exotoxin.

    W Debinski;N I Obiri;S K Powers;I Pastan

  • Intratumoral administration of recombinant circularly permuted interleukin-4-Pseudomonas exotoxin in patients with high-grade glioma.

    Robert W. Rand;Robert J. Kreitman;Nicholas Patronas;Frederick Varricchio

  • The interleukin-13 receptor α2 chain: an essential component for binding and internalization but not for interleukin-13–induced signal transduction through the STAT6 pathway

    Koji Kawakami;Jun Taguchi;Takashi Murata;Raj K. Puri

  • Medical applications of microarray technologies: a regulatory science perspective

    Emanuel F. Petricoin;Joseph L. Hackett;Lawrence J. Lesko;Raj K. Puri

  • Poor drug distribution as a possible explanation for the results of the PRECISE trial.

    John H. Sampson;Gary Archer;Christoph Pedain;Eva Wembacher-Schröder

  • Cross-platform comparability of microarray technology: intra-platform consistency and appropriate data analysis procedures are essential.

    Leming Shi;Weida Tong;Hong Fang;Uwe Scherf

  • Polypeptide components of two 8 S forms of chicken oviduct progesterone receptor

    J J Dougherty;R K Puri;D O Toft

  • Cell and gene therapies: moving from research to clinic

    David F Stroncek;Raj K Puri

Frequent Co-Authors

Ira Pastan
Ira Pastan Center for Cancer Research
Robert J. Kreitman
Robert J. Kreitman National Cancer Institute
Cory M. Hogaboam
Cory M. Hogaboam Cedars-Sinai Medical Center
Hong Fang
Hong Fang National Center for Toxicological Research
Mahendra S. Rao
Mahendra S. Rao National Institutes of Health
Leming Shi
Leming Shi Fudan University
Claudia Jakubzick
Claudia Jakubzick Dartmouth College
Roger Perkins
Roger Perkins United States Food and Drug Administration
John H. Sampson
John H. Sampson Duke University
Susan M. Chang
Susan M. Chang University of California, San Francisco

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