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Molecular Biology

D-Index
61
Citations
29862
World Ranking
1875
National Ranking
132

Overview

Heinz D. Osiewacz is affiliated with Goethe University Frankfurt in Germany. Their research predominantly focuses on biochemistry, genetics, and molecular biology, contributing to 44 publications in these fields, alongside 13 publications related to medicine. Within these broad areas, their work delves deeply into molecular biology, aging, epidemiology, cell biology, and physiology.

Their research explores several main topics, including mitochondrial function and pathology, genetics related to aging and longevity in model organisms, ATP synthase and ATPases, autophagy in disease and therapy, Alzheimer's disease research and treatments, photosynthetic processes and mechanisms, and porphyrin metabolism and disorders.

  • Classification and Nomenclature of Metacaspases and Paracaspases: No More Confusion with Caspases (2020, Molecular Cell)
  • Role of sorting nexin PaATG24 in autophagy, aging and development of Podospora anserina (2020, Mechanisms of Ageing and Development)
  • Impaired F1Fo-ATP-Synthase Dimerization Leads to the Induction of Cyclophilin D-Mediated Autophagy-Dependent Cell Death and Accelerated Aging (2021, Cells)
  • Mitochondrial Phospholipid Homeostasis Is Regulated by the i-AAA Protease PaIAP and Affects Organismic Aging (2021, Cells)
  • Disruption of the MICOS complex leads to an aberrant cristae structure and an unexpected, pronounced lifespan extension in Podospora anserina (2022, Journal of Cellular Biochemistry)

Frequent publication venues for their work include journals such as Cells, where they have published four papers, the Journal of Fungi with two publications, Biochimica et Biophysica Acta (BBA) - Bioenergetics, and Faculty Opinions - Post-Publication Peer Review of the Biomedical Literature with two papers each, as well as Molecular Cell.

They have collaborated multiple times with several coauthors, including Andréa Hamann (8 publications), Lea Schürmanns (5 publications), Verena Warnsmann (5 publications), Lisa-Marie Marschall (4 publications), and Anja C. Meeßen (3 publications).

Best Publications

  • Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)

    Daniel J. Klionsky;Amal Kamal Abdel-Aziz;Sara Abdelfatah;Mahmoud Abdellatif

  • Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

    Daniel J. Klionsky;Kotb Abdelmohsen;Akihisa Abe;Joynal Abedin

  • Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

    Daniel J. Klionsky;Kotb Abdelmohsen;Akihisa Abe;Joynal Abedin

  • Macromolecular organization of ATP synthase and complex I in whole mitochondria

    Karen M. Davies;Mike Strauss;Bertram Daum;Jan H. Kief

  • Reducing mitochondrial fission results in increased life span and fitness of two fungal ageing models.

    C Q Scheckhuber;N Erjavec;A Tinazli;A Hamann

  • Mitochondrial quality control: an integrated network of pathways.

    Fabian Fischer;Andrea Hamann;Heinz D. Osiewacz

  • Erratum to: Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) (Autophagy, 12, 1, 1-222, 10.1080/15548627.2015.1100356

    Daniel J. Klionsky;Kotb Abdelmohsen;Akihisa Abe;Joynal Abedin

  • Age-dependent dissociation of ATP synthase dimers and loss of inner-membrane cristae in mitochondria

    Bertram Daum;Andreas Walter;Angelika Horst;Heinz D. Osiewacz;Heinz D. Osiewacz

  • The mitochondrial plasmid of Podospora anserina: A mobile intron of a mitochondrial gene

    H. D. Osíewacz;K. Esser

  • De novo assembly of a 40 Mb eukaryotic genome from short sequence reads: Sordaria macrospora, a model organism for fungal morphogenesis.

    Minou Nowrousian;Jason E Stajich;Meiling Chu;Ines Engh

  • Loss of mitochondrial peptidase Clpp leads to infertility, hearing loss plus growth retardation via accumulation of CLPX, mtDNA and inflammatory factors

    Suzana Gispert;Dajana Parganlija;Michael Klinkenberg;Stefan Dröse

  • Guidelines and recommendations on yeast cell death nomenclature

    Didac Carmona-Gutierrez;Maria Anna Bauer;Andreas Zimmermann;Andrés Aguilera

  • Apoptosis pathways in fungal growth, development and ageing.

    Andrea Hamann;Diana Brust;Heinz D. Osiewacz

  • Molecular Biology of Fungal Development

    Heinz D. Osiewacz

  • Increasing organismal healthspan by enhancing mitochondrial protein quality control.

    Karin Luce;Heinz D. Osiewacz

  • Mating-type genes from the homothallic fungus Sordaria macrospora are functionally expressed in a heterothallic ascomycete

    Stefanie Pöggeler;Siegfried Risch;Ulrich Kück;Heinz D. Osiewacz

  • Copper-modulated gene expression and senescence in the filamentous fungus Podospora anserina.

    Corina Borghouts;Alexandra Werner;Thomas Elthon;Heinz D. Osiewacz

  • The onset of senescence is affected by DNA rearrangements of a discontinuous mitochondrial gene in Podospora anserina.

    Ulrich Kück;Heinz D. Osiewacz;Udo Schmidt;Birgit Kappelhoff

  • Supramolecular organization of cytochrome c oxidase- and alternative oxidase-dependent respiratory chains in the filamentous fungus Podospora anserina.

    Frank Krause;Christian Q. Scheckhuber;Alexandra Werner;Sascha Rexroth

  • Simultaneous impairment of mitochondrial fission and fusion reduces mitophagy and shortens replicative lifespan

    Dominik Bernhardt;Matthias Müller;Andreas S. Reichert;Heinz D. Osiewacz

Frequent Co-Authors

Andreas S. Reichert
Andreas S. Reichert Heinrich Heine University Düsseldorf
Boris Zhivotovsky
Boris Zhivotovsky Karolinska Institute
Norbert A. Dencher
Norbert A. Dencher Technical University of Darmstadt
Ina Koch
Ina Koch Goethe University Frankfurt
Evelina Gatti
Evelina Gatti Aix-Marseille University
Sergio Lavandero
Sergio Lavandero University of Chile
Karl Esser
Karl Esser Ruhr University Bochum
Maurizio Molinari
Maurizio Molinari Universita della Svizzera Italiana
Beth Levine
Beth Levine The University of Texas Southwestern Medical Center
Stefanie Pöggeler
Stefanie Pöggeler University of Göttingen

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