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Biology and Biochemistry

D-Index
67
Citations
18016
World Ranking
8136
National Ranking
3682

Overview

Mark W. Musch is affiliated with the University of Chicago in the United States. Their research primarily focuses on the interactions between diet, gut microbiota, and metabolic health, investigating how dietary patterns influence biological rhythms and disease development.

The scientist has published extensively in several fields, notably Medicine and Biochemistry, Genetics and Molecular Biology. Their specific subfields of study include Physiology, Molecular Biology, Endocrinology, Diabetes and Metabolism, Endocrine and Autonomic Systems, and Genetics.

The main topics covered in their work encompass:

  • Gut microbiota and health
  • Dietary Effects on Health
  • Diet and metabolism studies
  • Circadian rhythm and melatonin
  • Diet, Metabolism, and Disease
  • Diabetes and associated disorders
  • Gastrointestinal motility and disorders

Mark W. Musch has published research papers in several venues, including:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Cell Host & Microbe
  • The FASEB Journal
  • SSRN Electronic Journal

Frequent collaborators include Jun Miyoshi, Eugene B. Chang, Vanessa Leone, Katya Frazier, and Amal Kambal.

Notable recent papers authored or co-authored by Mark W. Musch include:

  • High-fat diet disrupts REG3γ and gut microbial rhythms promoting metabolic dysfunction, 2022, Cell Host & Microbe
  • High fat diet disrupts diurnal interactions between REG3γ and small intestinal gut microbes resulting in metabolic dysfunction, 2020, bioRxiv (Cold Spring Harbor Laboratory)
  • Development of early-stage type 1 diabetes in germ-free interleukin-10 deficient mice, 2020, bioRxiv (Cold Spring Harbor Laboratory)
  • High fat diet disrupts diurnal interactions between small intestinal host innate immune factor REG3γ and gut microbiota resulting in metabolic dysfunction, 2022, The FASEB Journal
  • Western Diet Disrupts REG3γ and Gut Microbial Rhythms Promoting Metabolic Dysfunction, 2020, SSRN Electronic Journal

Best Publications

  • Dietary-fat-induced taurocholic acid promotes pathobiont expansion and colitis in Il10 −/− mice

    Suzanne Devkota;Yunwei Wang;Mark W. Musch;Vanessa Leone

  • Effects of diurnal variation of gut microbes and high-fat feeding on host circadian clock function and metabolism.

    Vanessa Leone;Sean M. Gibbons;Sean M. Gibbons;Kristina Martinez;Alan L. Hutchison

  • Novel role of the vitamin D receptor in maintaining the integrity of the intestinal mucosal barrier

    Juan Kong;Zhongyi Zhang;Mark W. Musch;Gang Ning

  • Antibiotic-induced perturbations in gut microbial diversity influences neuro-inflammation and amyloidosis in a murine model of Alzheimer’s disease

    Myles R. Minter;Can Zhang;Vanessa Leone;Daina L. Ringus

  • Small Intestine Microbiota Regulate Host Digestive and Absorptive Adaptive Responses to Dietary Lipids

    Kristina Martinez-Guryn;Kristina Martinez-Guryn;Nathaniel Hubert;Katya Frazier;Saskia Urlass

  • Probiotics inhibit nuclear factor-κB and induce heat shock proteins in colonic epithelial cells through proteasome inhibition

    Elaine O. Petrof;Keishi Kojima;Mark J. Ropeleski;Mark W. Musch

  • Microbial signals drive pre-leukaemic myeloproliferation in a Tet2-deficient host.

    Marlies Meisel;Reinhard Hinterleitner;Alain Pacis;Li Chen

  • Recognition of host immune activation by Pseudomonas aeruginosa

    Licheng Wu;Oscar Estrada;Olga Zaborina;Manjeet Bains

  • Soluble factors from Lactobacillus GG activate MAPKs and induce cytoprotective heat shock proteins in intestinal epithelial cells

    Yun Tao;Kenneth A. Drabik;Tonya S. Waypa;Mark W. Musch

  • Intestinal epithelial vitamin D receptor signaling inhibits experimental colitis

    Weicheng Liu;Yunzi Chen;Yunzi Chen;Maya Aharoni Golan;Maria L. Annunziata

  • Antibiotic-induced perturbations in microbial diversity during post-natal development alters amyloid pathology in an aged APP SWE /PS1 ΔE9 murine model of Alzheimer’s disease

    Myles R. Minter;Reinhard Hinterleitner;Marlies Meisel;Can Zhang

  • Na+-K+-Cl- co-transport in the intestine of a marine teleost.

    Mark W. Musch;Stephanie A. Orellana;Leigh S. Kimberg;Michael Field

  • hPepT1 transports muramyl dipeptide, activating NF-κB and stimulating IL-8 secretion in human colonic Caco2/bbe cells

    Stephan R. Vavricka;Mark W. Musch;Jonathan E. Chang;Yasushi Nakagawa

  • The Bacillus subtilis Quorum-Sensing Molecule CSF Contributes to Intestinal Homeostasis via OCTN2, a Host Cell Membrane Transporter

    Mikihiro Fujiya;Mark W. Musch;Yasushi Nakagawa;Shien Hu

  • Na+/H+ exchangers, NHE-1 and NHE-3, of rat intestine. Expression and localization.

    Crescence Bookstein;Alex M. DePaoli;Yue Xie;Ping Niu

  • Gut-Derived Sepsis Occurs When the Right Pathogen With the Right Virulence Genes Meets the Right Host: Evidence for In Vivo Virulence Expression in Pseudomonas aeruginosa

    John Alverdy;Christopher Holbrook;Flavio Rocha;Louis Seiden

  • Coordinated epithelial NHE3 inhibition and barrier dysfunction are required for TNF-mediated diarrhea in vivo

    Daniel R. Clayburgh;Mark W. Musch;Michael Leitges;Yang Xin Fu

  • T cell activation causes diarrhea by increasing intestinal permeability and inhibiting epithelial Na+/K+-ATPase

    Mark W. Musch;Lane L. Clarke;Daniel Mamah;Lara R. Gawenis

  • Glutamine attenuates tumor necrosis factor-α release and enhances heat shock protein 72 in human peripheral blood mononuclear cells

    Paul E Wischmeyer;Jacob Riehm;Kristen D Singleton;Hongyu Ren

  • Regulation of Human CLC-3 Channels by Multifunctional Ca2+/Calmodulin-dependent Protein Kinase

    Ping Huang;Jie Liu;Anke Di;Nicole C. Robinson

Frequent Co-Authors

Eugene B. Chang
Eugene B. Chang University of Chicago
Marc Bissonnette
Marc Bissonnette University of Chicago
Bana Jabri
Bana Jabri University of Chicago
Jerrold R. Turner
Jerrold R. Turner Brigham and Women's Hospital
Chun-Su Yuan
Chun-Su Yuan University of Chicago
Richard J. Miller
Richard J. Miller Northwestern University
Masahiro Yamamoto
Masahiro Yamamoto Osaka University
Tong-Chuan He
Tong-Chuan He University of Chicago
Jack A. Gilbert
Jack A. Gilbert University of California, San Diego
Yong Huang
Yong Huang Hong Kong University of Science and Technology

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