John Orlowski

Overview

Best Publications

• Sensors and regulators of intracellular pH

  Joseph R. Casey;Sergio Grinstein;John Orlowski

  2256
  Citations

• Molecular cloning of putative members of the Na/H exchanger gene family. cDNA cloning, deduced amino acid sequence, and mRNA tissue expression of the rat Na/H exchanger NHE-1 and two structurally related proteins.

  J Orlowski;R.A. Kandasamy;G.E. Shull

  864
  Citations

• Diversity of the mammalian sodium/proton exchanger SLC9 gene family.

  John Orlowski;Sergio Grinstein

  760
  Citations

• Na+/H+ Exchangers of Mammalian Cells *

  John Orlowski;Sergio Grinstein

  720
  Citations

• Tissue-specific and developmental regulation of rat Na,K-ATPase catalytic alpha isoform and beta subunit mRNAs.

  J Orlowski;J B Lingrel

  647
  Citations

• Direct Binding of the Na–H Exchanger NHE1 to ERM Proteins Regulates the Cortical Cytoskeleton and Cell Shape Independently of H+ Translocation

  Sheryl P Denker;Derek C Huang;John Orlowski;Heinz Furthmayr

  575
  Citations

• Molecular genetics of Na,K-ATPase.

  Jerry B. Lingrel;John Orlowski;Marcia M. Shull;Elmer M. Price

  504
  Citations

• Identification of a Mitochondrial Na+/H+Exchanger

  Masayuki Numata;Kevin Petrecca;Norma Lake;John Orlowski

  392
  Citations

• Heterologous expression and functional properties of amiloride high affinity (NHE-1) and low affinity (NHE-3) isoforms of the rat Na/H exchanger.

  J Orlowski

  387
  Citations

• Functional characterization of three isoforms of the Na+/H+ exchanger stably expressed in Chinese hamster ovary cells. ATP dependence, osmotic sensitivity, and role in cell proliferation.

  A. Kapus;S. Grinstein;Sanjeev Wasan;Ramani Kandasamy

  360
  Citations

• Molecular Cloning and Characterization of a Novel (Na+,K+)/H+ Exchanger Localized to the trans-Golgi Network

  Masayuki Numata;John Orlowski

  346
  Citations

• Primary structure and functional expression of a novel gastrointestinal isoform of the rat Na/H exchanger.

  Zhuo Wang;J. Orlowski;G. E. Shull

  309
  Citations

• The epithelial sodium-hydrogen antiporter Na+/H+ exchanger 3 accumulates and is functional in recycling endosomes

  Sudhir D'Souza;Ana Garcia-Cabado;Frank Yu;Ken Teter

  251
  Citations

• Intracellular Ph Regulation by Na+/H+ Exchange Requires Phosphatidylinositol 4,5-Bisphosphate

  Orit Aharonovitz;Hans C. Zaun;Tamas Balla;John D. York

  251
  Citations

• Cytoplasmic Domain of the Ubiquitous Na+/H+ Exchanger NHE1 Can Confer Ca2+ Responsiveness to the Apical Isoform NHE3

  Shigeo Wakabayashi;Toshitaro Ikeda;Josette Noël;Bernhard Schmitt

  250
  Citations

• Endosomal Recycling of the Na+/H+Exchanger NHE3 Isoform Is Regulated by the Phosphatidylinositol 3-Kinase Pathway

  Kazuyoshi Kurashima;Elöd Z. Szabó;Gergely Lukacs;John Orlowski

  227
  Citations

• Focal localization of the NHE-1 isoform of the Na+/H+ antiport: assessment of effects on intracellular pH

  S. Grinstein;M. Woodside;T. K. Waddell;G. P. Downey

  211
  Citations

• Molecular Cloning, Genomic Organization, and Functional Expression of Na+/H+ Exchanger Isoform 5 (NHE5) from Human Brain

  Nancy R. Baird;John Orlowski;Elöd Z. Szabó;Hans C. Zaun

  211
  Citations

• Identification of sites required for down-regulation of Na+/H+ exchanger NHE3 activity by cAMP-dependent protein kinase. phosphorylation-dependent and -independent mechanisms.

  Kazuyoshi Kurashima;Frank H. Yu;Ana G. Cabado;Elöd Z. Szabó

  208
  Citations

• Functional properties of the rat Na/H exchanger NHE-2 isoform expressed in Na/H exchanger-deficient Chinese hamster ovary cells.

  F H Yu;G E Shull;J Orlowski

  198
  Citations