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Biology and Biochemistry

D-Index
53
Citations
14753
World Ranking
15960
National Ranking
6628

Research.com Recognitions

  • 2012 - Fellow of the American Association for the Advancement of Science (AAAS)

Overview

Diane L. Barber is affiliated with the University of California, San Francisco in the United States. Their research primarily lies within the field of Biochemistry, Genetics and Molecular Biology, with a focus on Molecular Biology, Cancer Research, Physiology, Cell Biology, and Neurology as notable subfields. The scientist's work broadly addresses topics such as Cancer, Hypoxia, and Metabolism, Pluripotent Stem Cells Research, ATP Synthase and ATPases Research, CRISPR and Genetic Engineering, RNA Research and Splicing, Calcium signaling and nucleotide metabolism, and Ion Transport and Channel Regulation.

Their recent publications include:

  • pHLARE: a new biosensor reveals decreased lysosome pH in cancer cells, 2020, Molecular Biology of the Cell
  • Intracellular pH Regulates Cancer and Stem Cell Behaviors: A Protein Dynamics Perspective, 2020, Frontiers in Oncology
  • Intracellular pH dynamics regulates intestinal stem cell lineage specification, 2023, Nature Communications
  • TCR signaling promotes formation of an STS1-Cbl-b complex with pH-sensitive phosphatase activity that suppresses T cell function in acidic environments, 2023, Immunity
  • An acidic residue buried in the dimer interface of isocitrate dehydrogenase 1 (IDH1) helps regulate catalysis and pH sensitivity, 2020, Biochemical Journal

Frequent co-authors in their collaborations include Bradley A. Webb, Katharine A. White, Todd Nystul, Francesca M. Aloisio, and Torsten Wittmann. The majority of their work has appeared in publication venues such as bioRxiv (Cold Spring Harbor Laboratory), Molecular Biology of the Cell, Immunity, Frontiers in Oncology, and Nature Communications.

Besides articles, Diane L. Barber has authored a book titled Organelles in Disease, published in 2023 by Springer Science+Business Media. They also hold the distinction of being recognized as a Fellow of the American Association for the Advancement of Science (AAAS) since 2012.

Best Publications

  • Dysregulated pH: a perfect storm for cancer progression.

    Bradley A. Webb;Michael Chimenti;Matthew P. Jacobson;Diane L. Barber

  • Dissecting the Tumor Myeloid Compartment Reveals Rare Activating Antigen-Presenting Cells Critical for T Cell Immunity

    Miranda L. Broz;Mikhail Binnewies;Bijan Boldajipour;Amanda E. Nelson

  • The changing face of the Na+/H+ exchanger, NHE1: structure, regulation, and cellular actions.

    L K Putney;S P Denker;D L Barber

  • Cell migration requires both ion translocation and cytoskeletal anchoring by the Na-H exchanger NHE1

    Sheryl P. Denker;Diane L. Barber

  • Direct Binding of the Na–H Exchanger NHE1 to ERM Proteins Regulates the Cortical Cytoskeleton and Cell Shape Independently of H+ Translocation

    Sheryl P Denker;Derek C Huang;John Orlowski;Heinz Furthmayr

  • Molecular Analysis of System N Suggests Novel Physiological Roles in Nitrogen Metabolism and Synaptic Transmission

    Farrukh A Chaudhry;Farrukh A Chaudhry;Richard J Reimer;David Krizaj;Diane Barber

  • Na-H exchange-dependent increase in intracellular pH times G2/M entry and transition.

    Luanna K. Putney;Diane L. Barber

  • Cancer cell behaviors mediated by dysregulated pH dynamics at a glance.

    Katharine A. White;Bree K. Grillo-Hill;Diane L. Barber

  • Intracellular pH Sensors: Design Principles and Functional Significance

    Jyoti Srivastava;Diane L. Barber;Matthew P. Jacobson

  • p160ROCK mediates RhoA activation of Na–H exchange

    Tomoko Tominaga;Toshimasa Ishizaki;Shuh Narumiya;Diane L. Barber

  • Na-H exchange acts downstream of RhoA to regulate integrin-induced cell adhesion and spreading.

    Tomoko Tominaga;Diane L. Barber

  • Dynamic actin remodeling during epithelial-mesenchymal transition depends on increased moesin expression.

    Jennifer Haynes;Jyoti Srivastava;Nikki Madson;Torsten Wittmann

  • Gα13 Stimulates Na+-H+ Exchange through Distinct Cdc42-dependent and RhoA-dependent Pathways

    Rebecca Hooley;Chun-Yuan Yu;Marc Symons;Diane L. Barber

  • G alpha 13 stimulates Na-H exchange.

    T Voyno-Yasenetskaya;B R Conklin;R L Gilbert;R Hooley

  • A human MAP kinase interactome

    Sourav Bandyopadhyay;Chih-yuan Chiang;Jyoti Srivastava;Merril Gersten

  • Cloning and sequence analysis of cDNA for the canine neurotensin/neuromedin N precursor

    Paul R. Dobner;Diane L. Barber;Lydia Villa-Komaroff;Colleen McKiernan

  • Cofilin is a pH sensor for actin free barbed end formation: role of phosphoinositide binding.

    Christian Frantz;Gabriela Barreiro;Laura Dominguez;Xiaoming Chen

  • A calcineurin homologous protein inhibits GTPase-stimulated Na-H exchange.

    Xia Lin;Diane L. Barber

  • Ion transport proteins anchor and regulate the cytoskeleton

    Sheryl P Denker;Diane L Barber

  • Na(+)/H(+) exchanger NHE1 as plasma membrane scaffold in the assembly of signaling complexes.

    Martin Baumgartner;Hitesh Patel;Diane L. Barber

Frequent Co-Authors

Matthew P. Jacobson
Matthew P. Jacobson University of California, San Francisco
Alan D. D'Andrea
Alan D. D'Andrea Dana-Farber Cancer Institute
Ryan D. Hernandez
Ryan D. Hernandez McGill University
Xia Lin
Xia Lin Baylor College of Medicine
John Orlowski
John Orlowski McGill University
Robert H. Insall
Robert H. Insall University of Glasgow
Don C. Lamb
Don C. Lamb Ludwig-Maximilians-Universität München
Sumit K. Chanda
Sumit K. Chanda Discovery Institute
Laura J. van't Veer
Laura J. van't Veer University of California, San Francisco
John Kuriyan
John Kuriyan Vanderbilt University

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