2012 - Fellow of the American Association for the Advancement of Science (AAAS)
His scientific interests lie mostly in DNA repair, Molecular biology, Fanconi anemia, Fanconi anemia, complementation group C and FANCD2. His DNA repair research is multidisciplinary, relying on both DNA damage and Genome instability. His Molecular biology research incorporates elements of Cell culture, Complementary DNA, Chromatin, Erythropoietin receptor and Phosphorylation.
His Fanconi anemia study combines topics from a wide range of disciplines, such as Cancer research, Disease, BRIP1, Cell cycle and Chromosome instability. His work deals with themes such as FANCG, FAN1 and FANCB, which intersect with Fanconi anemia, complementation group C. His studies deal with areas such as Ataxia-telangiectasia and Ubiquitin ligase as well as FANCD2.
His primary areas of investigation include Cancer research, Molecular biology, Fanconi anemia, DNA repair and Internal medicine. His Cancer research research focuses on subjects like PARP inhibitor, which are linked to Olaparib. His work focuses on many connections between Molecular biology and other disciplines, such as Erythropoietin receptor, that overlap with his field of interest in Cell culture and SOCS2.
His Fanconi anemia research is included under the broader classification of Genetics. His work carried out in the field of DNA repair brings together such families of science as Homologous recombination, DNA damage, Genome instability and Cell biology. His FANCD2 study incorporates themes from FANCM and Monoubiquitination.
His primary scientific interests are in Cancer research, Homologous recombination, PARP inhibitor, Cancer and DNA repair. His Cancer research research is multidisciplinary, relying on both DNA damage, Genome instability, Poly ADP ribose polymerase, Gene and Ovarian cancer. His research integrates issues of Synthetic lethality, Polymerase, Fanconi anemia and CRISPR in his study of Homologous recombination.
Alan D. D'Andrea interconnects Progenitor cell, Haematopoiesis and Cell biology in the investigation of issues within Fanconi anemia. Alan D. D'Andrea has included themes like RNA interference, Microsatellite instability and DNA replication in his DNA repair study. His DNA study combines topics in areas such as Molecular biology and Gene knockdown.
This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.
Activating mutation in the tyrosine kinase JAK2 in polycythemia vera, essential thrombocythemia, and myeloid metaplasia with myelofibrosis.
Ross L. Levine;Ross L. Levine;Martha Wadleigh;Jan Cools;Benjamin L. Ebert;Benjamin L. Ebert.
Cancer Cell (2005)
Interaction of the Fanconi anemia proteins and BRCA1 in a common pathway.
Irene Garcia-Higuera;Toshiyasu Taniguchi;Shridar Ganesan;M.Stephen Meyn.
Molecular Cell (2001)
Biallelic Inactivation of BRCA2 in Fanconi Anemia
Niall G. Howlett;Toshiyasu Taniguchi;Susan Olson;Barbara Cox.
Repair Pathway Choices and Consequences at the Double-Strand Break
Raphael Ceccaldi;Beatrice Rondinelli;Alan D. D’Andrea.
Trends in Cell Biology (2016)
Cloning of cDNA for the major DNA-binding protein of the erythroid lineage through expression in mammalian cells
Shih-Feng Tsai;David I. K. Martin;David I. K. Martin;Leonard I. Zon;Leonard I. Zon;Alan D. D'Andrea;Alan D. D'Andrea.
Expression cloning of the murine erythropoietin receptor.
Alan D. D'Andrea;Alan D. D'Andrea;Harvey F. Lodish;Gordon G. Wong.
The Fanconi anaemia/BRCA pathway
Alan D. D'Andrea;Markus Grompe.
Nature Reviews Cancer (2003)
Identification of the FANCI protein, a monoubiquitinated FANCD2 paralog required for DNA repair.
Agata Smogorzewska;Agata Smogorzewska;Shuhei Matsuoka;Patrizia Vinciguerra;E. Robert McDonald.
How the Fanconi Anemia Pathway Guards the Genome
George Lucian Moldovan;Alan D. D'Andrea.
Annual Review of Genetics (2009)
Disruption of the Fanconi anemia-BRCA pathway in cisplatin-sensitive ovarian tumors.
Toshiyasu Taniguchi;Marc Tischkowitz;Najim Ameziane;Shirley V. Hodgson.
Nature Medicine (2003)
If you think any of the details on this page are incorrect, let us know.
We appreciate your kind effort to assist us to improve this page, it would be helpful providing us with as much detail as possible in the text box below: