World's Best Scientists 2026 revealed!

D-Index & Metrics

Molecular Biology

D-Index
47
Citations
15320
World Ranking
2710
National Ranking
1313

Overview

Toshiyasu Taniguchi is affiliated with the Fred Hutchinson Cancer Research Center in the United States. Their research primarily focuses on the fields of biochemistry, genetics, and molecular biology, with a notable emphasis on molecular biology within these domains.

The scientist's main research topics include DNA repair mechanisms, CRISPR and genetic engineering, cancer-related molecular pathways, chromosomal and genetic variations, and cell image analysis techniques. These topics reflect a concentration on understanding and manipulating genetic material and cellular processes relevant to both fundamental biology and disease contexts.

Taniguchi has published work in a selection of scientific journals spanning diverse but interconnected disciplines. Frequent publication venues include Life Science Alliance, Nature Cell Biology, and Microscopy.

Among their recent papers are the following:

  • RFWD3 and translesion DNA polymerases contribute to PCNA modification-dependent DNA damage tolerance, 2022, Life Science Alliance
  • Maintenance of R-loop structures by phosphorylated hTERT preserves genome integrity, 2024, Nature Cell Biology
  • Semi-automated image acquisition and analyses for broad users utilizing macro keyboards, 2025, Microscopy

Collaboration is a component of their research activities, with frequent co-authors including Rie Kanao, Hidehiko Kawai, Minoru Takata, Chikahide Masutani, and Mitsuhiro Machitani.

Best Publications

  • Interaction of the Fanconi anemia proteins and BRCA1 in a common pathway.

    Irene Garcia-Higuera;Toshiyasu Taniguchi;Shridar Ganesan;M.Stephen Meyn

  • Biallelic Inactivation of BRCA2 in Fanconi Anemia

    Niall G. Howlett;Toshiyasu Taniguchi;Susan Olson;Barbara Cox

  • Secondary mutations as a mechanism of cisplatin resistance in BRCA2 -mutated cancers

    Wataru Sakai;Elizabeth M. Swisher;Beth Y. Karlan;Mukesh K. Agarwal

  • Disruption of the Fanconi anemia-BRCA pathway in cisplatin-sensitive ovarian tumors.

    Toshiyasu Taniguchi;Marc Tischkowitz;Najim Ameziane;Shirley V. Hodgson

  • Secondary Somatic Mutations Restoring BRCA1/2 Predict Chemotherapy Resistance in Hereditary Ovarian Carcinomas

    Barbara Norquist;Kaitlyn A. Wurz;Christopher C. Pennil;Rochelle Garcia

  • Convergence of the fanconi anemia and ataxia telangiectasia signaling pathways.

    Toshiyasu Taniguchi;Irene Garcia-Higuera;Bo Xu;Paul R. Andreassen

  • S-phase–specific interaction of the Fanconi anemia protein, FANCD2, with BRCA1 and RAD51

    Toshiyasu Taniguchi;Irene Garcia-Higuera;Irene Garcia-Higuera;Paul R. Andreassen;Paul R. Andreassen;Richard C. Gregory;Richard C. Gregory

  • Gene expression profile of BRCAness that correlates with responsiveness to chemotherapy and with outcome in patients with epithelial ovarian cancer.

    Panagiotis A. Konstantinopoulos;Dimitrios Spentzos;Beth Y. Karlan;Toshiyasu Taniguchi

  • Secondary BRCA1 Mutations in BRCA1-Mutated Ovarian Carcinomas with Platinum Resistance

    Elizabeth M. Swisher;Wataru Sakai;Beth Y. Karlan;Kaitlyn Wurz

  • ATR couples FANCD2 monoubiquitination to the DNA-damage response

    Paul R. Andreassen;Alan D. D'Andrea;Toshiyasu Taniguchi

  • Positional Cloning of a Novel Fanconi Anemia Gene, FANCD2

    Cynthia Timmers;Toshiyasu Taniguchi;James Hejna;Carol Reifsteck

  • Molecular pathogenesis of Fanconi anemia: recent progress.

    Toshiyasu Taniguchi;Alan D. D'Andrea;Alan D. D'Andrea

  • Human Fanconi anemia monoubiquitination pathway promotes homologous DNA repair

    Koji Nakanishi;Yun-Gui Yang;Andrew J. Pierce;Toshiyasu Taniguchi

  • Cancer Survivorship—Genetic Susceptibility and Second Primary Cancers: Research Strategies and Recommendations

    Lois B. Travis;Charles S. Rabkin;Linda Morris Brown;James M. Allan

  • Interaction of FANCD2 and NBS1 in the DNA damage response

    Koji Nakanishi;Toshiyasu Taniguchi;Velvizhi Ranganathan;Helen V. New

  • Functional restoration of BRCA2 protein by secondary BRCA2 mutations in BRCA2-mutated ovarian carcinoma.

    Wataru Sakai;Elizabeth M. Swisher;Céline Jacquemont;Kurapaty Venkatapoorna Chandramohan

  • The Fanconi anemia pathway is required for the DNA replication stress response and for the regulation of common fragile site stability

    Niall G. Howlett;Toshiyasu Taniguchi;Sandra G. Durkin;Alan D. D'Andrea

  • Chemosensitization to cisplatin by inhibitors of the Fanconi anemia/BRCA pathway

    Deborah Chirnomas;Toshiyasu Taniguchi;Michelle De La Vega;Ami P. Vaidya

  • Proteasome function is required for DNA damage response and fanconi anemia pathway activation.

    Céline Jacquemont;Toshiyasu Taniguchi

  • Ataxia-Pancytopenia Syndrome Is Caused by Missense Mutations in SAMD9L.

    Dong Hui Chen;Jennifer E. Below;Akiko Shimamura;Sioban B. Keel

Frequent Co-Authors

Alan D. D'Andrea
Alan D. D'Andrea Dana-Farber Cancer Institute
Markus Grompe
Markus Grompe Oregon Health & Science University
Elizabeth M. Swisher
Elizabeth M. Swisher University of Washington
Beth Y. Karlan
Beth Y. Karlan University of California, Los Angeles
Susan B. Olson
Susan B. Olson Oregon Health & Science University
Toshiro Fujita
Toshiro Fujita University of Tokyo
Christopher J. Kemp
Christopher J. Kemp Fred Hutchinson Cancer Research Center
Koji Nakanishi
Koji Nakanishi Columbia University
Muneesh Tewari
Muneesh Tewari University of Michigan–Ann Arbor
Hans Joenje
Hans Joenje VU University Medical Center

If you think any of the details on this page are incorrect, let us know.

Report an issue

We appreciate your kind effort to assist us to improve this page, it would be helpful providing us with as much detail as possible in the text box below:

Related Online Degrees & Career Pathways

A background in molecular biology can open doors to a wide range of career fields, both in laboratory research and in applied health sciences. Many students interested in expanding their skills look for accessible and flexible online degree options. If you are considering a shift toward healthcare, there are accelerated nursing programs for non nurses online which can help molecular biology graduates transition quickly into nursing roles.

Another option to explore involves the communication sciences. If you do not have an undergraduate background in the field but want to pursue speech-language pathology, several online speech-language pathology prerequisites program choices make it possible to meet the necessary requirements. Graduates may then apply for asha accredited online slp master's programs to move into professional SLP roles.

For those interested in mental health, combining a molecular biology background with advanced nursing can prove valuable. Psychiatric nurse practitioners are in high demand, and you can learn more about compensation and state-by-state opportunities on the dnp pmhnp salary page.

Best Scientists Citing Toshiyasu Taniguchi

Trending Scientists

Recently Published Articles