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Dipanjan Chowdhury

Dipanjan Chowdhury

D-Index & Metrics

Biology and Biochemistry

D-Index
59
Citations
16486
World Ranking
12349
National Ranking
5286

Research.com Recognitions

  • 2009 - OSA Fellows For optics publications, a distinguished record of consistent engineering-oriented ideas for telecommunication fiber optics, and an outstanding management ability, all contributing significantly toward the advancement of optics.

Overview

Dipanjan Chowdhury is affiliated with Harvard University in the United States, where the focus of their research spans several interconnected areas within biochemistry, genetics, molecular biology, and medicine.

Their main fields of study include:

  • Biochemistry, Genetics and Molecular Biology
  • Medicine

Within these fields, their subfields of study encompass:

  • Molecular Biology
  • Cancer Research
  • Oncology
  • Reproductive Medicine
  • Genetics

Dipanjan Chowdhury's work explores various scientific topics, focusing primarily on:

  • DNA Repair Mechanisms
  • PARP inhibition in cancer therapy
  • MicroRNA in disease regulation
  • Cancer-related molecular mechanisms research
  • Ovarian cancer diagnosis and treatment
  • RNA modifications and cancer
  • Biochemical and Molecular Research

The scientist has contributed to multiple research papers, including several prominent recent publications such as:

  • "Immunogenomic profiling determines responses to combined PARP and PD-1 inhibition in ovarian cancer" (2020) published in Nature Communications
  • "Targeting replication stress in cancer therapy" (2022) published in Nature Reviews Drug Discovery
  • "Berzosertib plus gemcitabine versus gemcitabine alone in platinum-resistant high-grade serous ovarian cancer: a multicentre, open-label, randomised, phase 2 trial" (2020) published in The Lancet Oncology
  • "TRIP13 regulates DNA repair pathway choice through REV7 conformational change" (2020) published in Nature Cell Biology
  • "A druggable addiction to de novo pyrimidine biosynthesis in diffuse midline glioma" (2022) published in Cancer Cell

The venues in which they frequently publish include:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Nature Communications
  • Cancer Research
  • Molecular Cell
  • Neuro-Oncology

Dipanjan Chowdhury often collaborates with several researchers, with frequent co-authors being:

  • Alan D. D'Andrea
  • Panagiotis A. Konstantinopoulos
  • Wojciech Fendler
  • Daphne A. Haas-Kogan
  • Huy Nguyen

In 2009, Dipanjan Chowdhury received the OSA Fellows award, recognized for contributions toward the advancement of optics in telecommunication fiber optics, including a distinguished record of engineering-oriented ideas and management ability in the field.

Best Publications

  • Antibody mediated in vivo delivery of small interfering RNAs via cell-surface receptors

    Erwei Song;Pengcheng Zhu;Sang Kyung Lee;Dipanjan Chowdhury

  • DNA breaks and chromosome pulverization from errors in mitosis

    Karen Crasta;Neil J. Ganem;Neil J. Ganem;Regina Dagher;Regina Dagher;Alexandra B. Lantermann

  • Death by a thousand cuts: granzyme pathways of programmed cell death.

    Dipanjan Chowdhury;Judy Lieberman

  • Mutations in the gene encoding the 3'-5' DNA exonuclease TREX1 are associated with systemic lupus erythematosus.

    Min Ae Lee-Kirsch;Maolian Gong;Dipanjan Chowdhury;Lydia Senenko

  • Association and prognostic significance of BRCA1/2-mutation status with neoantigen load, number of tumor-infiltrating lymphocytes and expression of PD-1/PD-L1 in high grade serous ovarian cancer.

    Kyle C. Strickland;Brooke E Howitt;Sachet A Shukla;Scott J. Rodig

  • γ-H2AX Dephosphorylation by Protein Phosphatase 2A Facilitates DNA Double-Strand Break Repair

    Dipanjan Chowdhury;Michael-Christopher Keogh;Haruhiko Ishii;Craig L. Peterson

  • miR-24 Inhibits Cell Proliferation by Targeting E2F2, MYC, and Other Cell-Cycle Genes via Binding to “Seedless” 3′UTR MicroRNA Recognition Elements

    Ashish Lal;Francisco Navarro;Christopher A. Maher;Laura E. Maliszewski

  • A phosphatase complex that dephosphorylates γH2AX regulates DNA damage checkpoint recovery

    Michael Christopher Keogh;Jung Ae Kim;Michael Downey;Jeffrey Fillingham

  • An siRNA-based microbicide protects mice from lethal herpes simplex virus 2 infection

    Deborah Palliser;Dipanjan Chowdhury;Qing Yin Wang;Sandra J. Lee

  • miR-182-Mediated Downregulation of BRCA1 Impacts DNA Repair and Sensitivity to PARP Inhibitors

    Patryk Moskwa;Francesca M. Buffa;Yunfeng Pan;Rohit Panchakshari

  • miR-24-mediated downregulation of H2AX suppresses DNA repair in terminally differentiated blood cells.

    Ashish Lal;Yunfeng Pan;Francisco Navarro;Derek M Dykxhoorn

  • The exonuclease TREX1 is in the SET complex and acts in concert with NM23-H1 to degrade DNA during granzyme A-mediated cell death.

    Dipanjan Chowdhury;Paul J. Beresford;Pengcheng Zhu;Dong Zhang

  • A PP4-Phosphatase Complex Dephosphorylates γ-H2AX Generated during DNA Replication

    Dipanjan Chowdhury;Xingzhi Xu;Xueyan Zhong;Fariyal Ahmed

  • Stabilization of mutant BRCA1 protein confers PARP inhibitor and platinum resistance.

    Neil Johnson;Shawn F. Johnson;Wei Yao;Yu Chen Li

  • Stepwise activation of the immunoglobulin μ heavy chain gene locus

    Dipanjan Chowdhury;Ranjan Sen

  • A mutation in TREX1 that impairs susceptibility to granzyme A-mediated cell death underlies familial chilblain lupus

    Min Ae Lee-Kirsch;Dipanjan Chowdhury;Scott Harvey;Maoliang Gong

  • Immunogenomic profiling determines responses to combined PARP and PD-1 inhibition in ovarian cancer.

    Anniina Färkkilä;Doga C. Gulhan;Julia Casado;Connor A. Jacobson

  • Pax5 is required for recombination of transcribed, acetylated, 5′ IgH V gene segments

    David G.T. Hesslein;David L. Pflugh;Dipanjan Chowdhury;Alfred L. M. Bothwell

  • DYNLL1 binds to MRE11 to limit DNA end resection in BRCA1-deficient cells

    Yizhou Joseph He;Khyati Meghani;Marie-Christine Caron;Chunyu Yang

  • A PP4 phosphatase complex dephosphorylates RPA2 to facilitate DNA repair via homologous recombination

    Dong Hyun Lee;Yunfeng Pan;Shlomo Kanner;Patrick Sung

Frequent Co-Authors

Judy Lieberman
Judy Lieberman Boston Children's Hospital
Alan D. D'Andrea
Alan D. D'Andrea Dana-Farber Cancer Institute
Ursula A. Matulonis
Ursula A. Matulonis Harvard University
Elizabeth M. Swisher
Elizabeth M. Swisher University of Washington
Geoffrey I. Shapiro
Geoffrey I. Shapiro Harvard University
Vassilis G. Gorgoulis
Vassilis G. Gorgoulis National and Kapodistrian University of Athens
David Pellman
David Pellman Howard Hughes Medical Institute
Massimo Loda
Massimo Loda Cornell University
Sachet A. Shukla
Sachet A. Shukla The University of Texas MD Anderson Cancer Center
Todd R. Golub
Todd R. Golub Harvard University

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