What is she best known for?
The fields of study she is best known for:
- Gene
- Mutation
- Immune system
Her scientific interests lie mostly in Immunology, Immunodeficiency, CD40, Molecular biology and Cytidine deaminase.
Her study in Immunology is interdisciplinary in nature, drawing from both P110δ and Bronchiectasis.
Anne Durandy has researched Immunodeficiency in several fields, including Partial albinism, Immunosuppression and Bone marrow.
Her CD40 study integrates concerns from other disciplines, such as Retinoid X receptor, CD86, Antigen and Cell biology.
Her Molecular biology research is multidisciplinary, incorporating elements of Tumor necrosis factor alpha, Recombinant DNA, Mutation, T cell and Biochemistry.
Anne Durandy has researched Cytidine deaminase in several fields, including Hemolytic anemia, Somatic hypermutation, Activation-induced deaminase and Hyper IgM syndrome.
Her most cited work include:
- Activation-induced cytidine deaminase (AID) deficiency causes the autosomal recessive form of the Hyper-IgM syndrome (HIGM2). (1344 citations)
- Impairment of mycobacterial immunity in human interleukin-12 receptor deficiency (751 citations)
- X-linked anhidrotic ectodermal dysplasia with immunodeficiency is caused by impaired NF-kappaB signaling. (660 citations)
What are the main themes of her work throughout her whole career to date?
Her main research concerns Immunology, Molecular biology, Immunoglobulin class switching, Antibody and Cytidine deaminase.
Her research integrates issues of Hyper IgM syndrome and CD40 in her study of Immunology.
Anne Durandy works mostly in the field of Molecular biology, limiting it down to topics relating to B cell and, in certain cases, Cancer research.
Anne Durandy focuses mostly in the field of Immunoglobulin class switching, narrowing it down to topics relating to DNA repair and, in certain cases, DNA ligase.
Her work carried out in the field of Antibody brings together such families of science as Immunopathology and Lymphocyte.
The study incorporates disciplines such as Somatic hypermutation and Activation-induced deaminase in addition to Cytidine deaminase.
She most often published in these fields:
- Immunology (61.69%)
- Molecular biology (52.24%)
- Immunoglobulin class switching (41.29%)
What were the highlights of her more recent work (between 2010-2020)?
- Immunology (61.69%)
- Molecular biology (52.24%)
- Immunoglobulin class switching (41.29%)
In recent papers she was focusing on the following fields of study:
Immunology, Molecular biology, Immunoglobulin class switching, B cell and Activation-induced deaminase are her primary areas of study.
Her Immunology research includes elements of Mutation and CD40.
Her work in Molecular biology covers topics such as DNA repair which are related to areas like Isotype, Genetic disorder, Polymerase and Protein subunit.
Her studies in Immunoglobulin class switching integrate themes in fields like Cell biology and Somatic cell.
Her Activation-induced deaminase research is multidisciplinary, incorporating perspectives in Central tolerance and Cytidine deaminase.
Her biological study spans a wide range of topics, including Somatic hypermutation and Immune tolerance.
Between 2010 and 2020, her most popular works were:
- Phosphoinositide 3-Kinase δ Gene Mutation Predisposes to Respiratory Infection and Airway Damage (370 citations)
- Autosomal dominant STAT3 deficiency and hyper-IgE syndrome: molecular, cellular, and clinical features from a French national survey. (200 citations)
- A human immunodeficiency caused by mutations in the PIK3R1 gene (159 citations)
In her most recent research, the most cited papers focused on:
- Gene
- Mutation
- Immune system
Anne Durandy mainly focuses on Immunology, B cell, Molecular biology, Mutation and Naive B cell.
Her Immunology research incorporates themes from P110δ, Bronchiectasis and Pneumonia.
Her work deals with themes such as T cell, Signal transduction and Primary and secondary antibodies, which intersect with B cell.
Her research in Molecular biology intersects with topics in Genetics, Genetic disorder, Protein kinase B and DNA repair.
Her Antibody study focuses mostly on Immunoglobulin class switching, Somatic hypermutation, Cytidine deaminase and Activation-induced deaminase.
She interconnects Immune system and Immunoglobulin Class Switch Recombination in the investigation of issues within Cytidine deaminase.
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