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Jean-Paul Mornon

Jean-Paul Mornon

D-Index & Metrics

Biology and Biochemistry

D-Index
68
Citations
16001
World Ranking
7816
National Ranking
259

Overview

Jean-Paul Mornon is affiliated with Sorbonne University in France, focusing on research areas within Medicine as well as Biochemistry, Genetics and Molecular Biology. Their subfields of study include Pulmonary and Respiratory Medicine, Molecular Biology, Genetics, Oncology, and Pediatrics, Perinatology and Child Health.

The scientist's research centers primarily on cystic fibrosis and related molecular mechanisms, covering topics such as Cystic Fibrosis Research Advances, Bacterial Genetics and Biotechnology, Protein Structure and Dynamics, Neonatal Respiratory Health Research, Advanced Biosensing and Bioanalysis Techniques, Drug Transport and Resistance Mechanisms, and RNA and Protein Synthesis Mechanisms.

Frequent publication venues for Jean-Paul Mornon's work include Cellular and Molecular Life Sciences, Scientific Reports, Biomolecules, European Journal of Medicinal Chemistry, and Frontiers in Pharmacology.

Notable recent papers authored or co-authored by Jean-Paul Mornon include:

  • Pharmacological chaperones improve intra-domain stability and inter-domain assembly via distinct binding sites to rescue misfolded CFTR (2021, Cellular and Molecular Life Sciences)
  • Digging into the 3D Structure Predictions of AlphaFold2 with Low Confidence: Disorder and Beyond (2022, Biomolecules)
  • Targeting different binding sites in the CFTR structures allows to synergistically potentiate channel activity (2020, European Journal of Medicinal Chemistry)
  • New insights into structure and function of bis-phosphinic acid derivatives and implications for CFTR modulation (2021, Scientific Reports)
  • Functional and Pharmacological Characterization of the Rare CFTR Mutation W361R (2020, Frontiers in Pharmacology)

Their collaborations include frequent co-authors such as Isabelle Callebaut, Ahmad Elbahnsi, B. Chevalier, Alexandre Hinzpeter, and Iwona Pranke, contributing to multiple publications across related fields.

Best Publications

  • Hydrophobic cluster analysis: an efficient new way to compare and analyse amino acid sequences

    C. Gaboriaud;V. Bissery;T. Benchetrit;J.P. Mornon

  • Conserved catalytic machinery and the prediction of a common fold for several families of glycosyl hydrolases

    Bernard Henrissat;Isabelle Callebaut;Sylvie Fabrega;Pierre Lehn

  • Molecular cloning and characterization of MPL, the human homolog of the v-mpl oncogene: identification of a member of the hematopoietic growth factor receptor superfamily.

    Isabelle Vigon;Jean-Paul Mornon;Laurence Cocault;Marie-Therese Mitjavila

  • From BRCA1 to RAP1: a widespread BRCT module closely associated with DNA repair

    Isabelle Callebaut;Jean-Paul Mornon

  • Deciphering protein sequence information through hydrophobic cluster analysis (HCA): current status and perspectives.

    I. Callebaut;G. Labesse;P. Durand;A. Poupon

  • Cellulase families revealed by hydrophobic cluster analysis.

    B. Henrissat;M. Claeyssens;P. Tomme;L. Lemesle

  • Metallo-β-lactamase fold within nucleic acids processing enzymes: the β-CASP family

    Isabelle Callebaut;Despina Moshous;Jean‐Paul Mornon;Jean‐Pierre de Villartay

  • The Ig-like Structure of the C-Terminal Domain of Lamin A/C, Mutated in Muscular Dystrophies, Cardiomyopathy, and Partial Lipodystrophy

    Isabelle Krimm;Cecilia Östlund;Bernard Gilquin;Joël Couprie

  • Hydrophobic cluster analysis: procedures to derive structural and functional information from 2-D-representation of protein sequences

    L. Lemesle-Varloot;B. Henrissat;C. Gaboriaud;C. Gaboriaud;V. Bissery

  • The immunoglobulin fold family: sequence analysis and 3D structure comparisons.

    D.M. Halaby;A. Poupon;J.-P. Mornon

  • The characterization of murine BCMA gene defines it as a new member of the tumor necrosis factor receptor superfamily.

    C Madry;Y Laabi;I Callebaut;J Roussel

  • The BAH (bromo-adjacent homology) domain: a link between DNA methylation, replication and transcriptional regulation

    Isabelle Callebaut;Jean-Claude Courvalin;Jean-Paul Mornon

  • The Hedgehog-inducible ubiquitin ligase subunit WSB-1 modulates thyroid hormone activation and PTHrP secretion in the developing growth plate.

    Monica Dentice;Amitabha Bandyopadhyay;Balázs Gereben;Isabelle Callebaut

  • An immunophilin that binds M(r) 90,000 heat shock protein: main structural features of a mammalian p59 protein.

    Isabelle Callebaut;Jack-Michel Renoir;Marie-Claire Lebeau;Nelly Massol

  • The immunoglobulin superfamily: An insight on its tissular, species, and functional diversity

    D. M. Halaby;J. P. E. Mornon

  • Rhenium Carbonyl Complexes of .beta.-Estradiol Derivatives with High Affinity for the Estradiol Receptor: An Approach to Selective Organometallic Radiopharmaceuticals

    Siden Top;Hassane El Hafa;Anne Vessieres;Jacques Quivy

  • The N-termini of FAK and JAKs contain divergent band 4.1 domains.

    Jean-Antoine Girault;Gilles Labesse;Jean-Paul Mornon;Isabelle Callebaut

  • Molecular models of the open and closed states of the whole human CFTR protein.

    Jean-Paul Mornon;Pierre Lehn;Isabelle Callebaut

  • Structural symmetry of the extracellular domain of the cytokine/growth hormone/prolactin receptor family and interferon receptors revealed by hydrophobic cluster analysis.

    E. Thoreau;B. Petridou;P.A. Kelly;J. Djiane

  • Steroid hormone receptors and pharmacology

    J.P. Raynaud;M.M. Bouton;M. Moguilewsky;T. Ojasoo

Frequent Co-Authors

Isabelle Callebaut
Isabelle Callebaut Sorbonne University
Bernard Henrissat
Bernard Henrissat Technical University of Denmark
Gilles Labesse
Gilles Labesse Grenoble Alpes University
Arsène Burny
Arsène Burny Université Libre de Bruxelles
Jean-Pierre de Villartay
Jean-Pierre de Villartay Université Paris Cité
Daniel Portetelle
Daniel Portetelle University of Liège
Alain Fischer
Alain Fischer Collège de France
Edwin Milgrom
Edwin Milgrom Grenoble Alpes University
Jean-François Zagury
Jean-François Zagury heSam Université

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