What is she best known for?
The fields of study she is best known for:
Isabelle Callebaut mainly focuses on Genetics, Cell biology, Biochemistry, Sequence analysis and Molecular biology.
Her studies in Genetics integrate themes in fields like Molecular model, Melatonin and Computational biology.
Her Cell biology research includes elements of Exocytosis and Tudor domain.
Her Biochemistry study deals with Biophysics intersecting with Mutation, Intracellular, Transporter and Binding protein.
Her Sequence analysis course of study focuses on Eukaryotic DNA replication and DNA methylation, Transcriptional regulation and Homology.
Her Molecular biology research includes themes of LIG4 syndrome, Replication protein A, DCLRE1C Gene, DCLRE1C and Complementary DNA.
Her most cited work include:
- Artemis, a Novel DNA Double-Strand Break Repair/V(D)J Recombination Protein, Is Mutated in Human Severe Combined Immune Deficiency (745 citations)
- Munc13-4 Is Essential for Cytolytic Granules Fusion and Is Mutated in a Form of Familial Hemophagocytic Lymphohistiocytosis (FHL3) (743 citations)
- From BRCA1 to RAP1: a widespread BRCT module closely associated with DNA repair (478 citations)
What are the main themes of her work throughout her whole career to date?
The scientist’s investigation covers issues in Genetics, Cell biology, Molecular biology, Biochemistry and Gene.
Genetics is represented through her Sequence analysis, Mutation, Missense mutation, DNA repair and DNA research.
Her Mutation research incorporates elements of Cancer research and Cystic fibrosis transmembrane conductance regulator.
Isabelle Callebaut is interested in GTPase, which is a field of Cell biology.
Her Molecular biology study combines topics in areas such as Epitope, Bovine leukemia virus, Binding domain and Complementary DNA.
Biochemistry is closely attributed to Biophysics in her study.
She most often published in these fields:
- Genetics (26.72%)
- Cell biology (19.47%)
- Molecular biology (18.70%)
What were the highlights of her more recent work (between 2015-2021)?
- Mutation (12.60%)
- Cell biology (19.47%)
- Immunology (7.25%)
In recent papers she was focusing on the following fields of study:
Her main research concerns Mutation, Cell biology, Immunology, Cystic fibrosis and Cystic fibrosis transmembrane conductance regulator.
Her Mutation research is within the category of Genetics.
Genetics connects with themes related to Molecular biology in her study.
Her Cell biology research is multidisciplinary, relying on both Biochemistry, Major facilitator superfamily, Telomere, Transcription and DNA replication.
Her work in Immunology addresses subjects such as Germline, which are connected to disciplines such as Common variable immunodeficiency.
Her Cystic fibrosis transmembrane conductance regulator research is multidisciplinary, incorporating perspectives in Biophysics, Mutant, Function and ATP-binding cassette transporter.
Between 2015 and 2021, her most popular works were:
- Disease-associated mutations identify a novel region in human STING necessary for the control of type I interferon signaling (87 citations)
- Inherited CD70 deficiency in humans reveals a critical role for the CD70–CD27 pathway in immunity to Epstein-Barr virus infection (71 citations)
- Shared genetic predisposition in rheumatoid arthritis-interstitial lung disease and familial pulmonary fibrosis. (70 citations)
In her most recent research, the most cited papers focused on:
Her primary areas of investigation include Immunology, Mutation, Cancer research, Exome sequencing and Cystic fibrosis transmembrane conductance regulator.
Her work in the fields of Immunology, such as Myeloid, B cell and Common variable immunodeficiency, overlaps with other areas such as Mechanism.
Her biological study spans a wide range of topics, including Molecular biology, Gene knockdown, Microcephaly and DNA repair.
Her Cancer research study combines topics from a wide range of disciplines, such as Congenital Neutropenia, Exocrine pancreatic insufficiency, Shwachman–Diamond syndrome, Unfolded protein response and Membrane protein.
Her study in Exome sequencing is interdisciplinary in nature, drawing from both Fanconi anemia, Rheumatoid arthritis, Genetic predisposition and Pathology.
Her Cystic fibrosis transmembrane conductance regulator research focuses on ATP-binding cassette transporter and how it connects with Drug discovery, Computational biology, In silico, Function and Cystic fibrosis.
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