What is she best known for?
The fields of study she is best known for:
Geneviève de Saint Basile mainly focuses on Immunology, Cell biology, Exocytosis, Hematopoietic stem cell transplantation and Degranulation.
The various areas that Geneviève de Saint Basile examines in her Immunology study include Mutation and Histopathology.
In her study, which falls under the umbrella issue of Cell biology, Cell killing, Lymphocyte and Cell Degranulation is strongly linked to Immunological synapse.
She has included themes like Survival rate, Gastroenterology, Single Center, Familial Hemophagocytic Lymphohistiocytosis and Severe combined immunodeficiency in her Hematopoietic stem cell transplantation study.
Geneviève de Saint Basile works mostly in the field of Single Center, limiting it down to topics relating to Hemophagocytosis and, in certain cases, Hemophagocytic lymphohistiocytosis.
Her studies in Degranulation integrate themes in fields like Granule, Lymphokine-activated killer cell and Effector.
Her most cited work include:
- Munc13-4 Is Essential for Cytolytic Granules Fusion and Is Mutated in a Form of Familial Hemophagocytic Lymphohistiocytosis (FHL3) (743 citations)
- CD40-CD40L independent Ig gene hypermutation suggests a second B cell diversification pathway in humans (365 citations)
- Munc18-2 deficiency causes familial hemophagocytic lymphohistiocytosis type 5 and impairs cytotoxic granule exocytosis in patient NK cells. (271 citations)
What are the main themes of her work throughout her whole career to date?
Her scientific interests lie mostly in Immunology, Hemophagocytic lymphohistiocytosis, Perforin, Cell biology and Genetics.
Her Immunology study combines topics in areas such as Mutation and Severe combined immunodeficiency.
Her study in Hemophagocytic lymphohistiocytosis is interdisciplinary in nature, drawing from both Immunopathology, CD8, Pediatrics and Familial Hemophagocytic Lymphohistiocytosis.
Her study looks at the relationship between Perforin and topics such as Cell activation, which overlap with Cytokine and Lymphocyte homeostasis.
Her research integrates issues of Exocytosis, Immunological synapse, Degranulation and Granule in her study of Cell biology.
Her work carried out in the field of Exocytosis brings together such families of science as Endosome and Lymphocyte.
She most often published in these fields:
- Immunology (96.69%)
- Hemophagocytic lymphohistiocytosis (62.91%)
- Perforin (41.72%)
What were the highlights of her more recent work (between 2014-2021)?
- Immunology (96.69%)
- Hemophagocytic lymphohistiocytosis (62.91%)
- Immunopathology (23.18%)
In recent papers she was focusing on the following fields of study:
Geneviève de Saint Basile spends much of her time researching Immunology, Hemophagocytic lymphohistiocytosis, Immunopathology, T cell and Perforin.
Her Immunology research is multidisciplinary, relying on both Mutation and Inflammatory bowel disease.
The Hemophagocytic lymphohistiocytosis study combines topics in areas such as Cytopenia, Familial Hemophagocytic Lymphohistiocytosis and UNC13D.
Her Cytopenia study integrates concerns from other disciplines, such as Inflammation, Myeloproliferative Disorders and CD8.
Geneviève de Saint Basile combines subjects such as Wolman disease, Gene mutation, Lymphocyte, Lymphoma and Genetic testing with her study of Familial Hemophagocytic Lymphohistiocytosis.
Her Pathogenesis research incorporates elements of Virus, CTL*, Immune disorder and Lymphocytic choriomeningitis.
Between 2014 and 2021, her most popular works were:
- Therapeutic effect of JAK1/2 blockade on the manifestations of hemophagocytic lymphohistiocytosis in mice (100 citations)
- Therapeutic effect of JAK1/2 blockade on the manifestations of hemophagocytic lymphohistiocytosis in mice (100 citations)
- Therapeutic effect of JAK1/2 blockade on the manifestations of hemophagocytic lymphohistiocytosis in mice (100 citations)
In her most recent research, the most cited papers focused on:
The scientist’s investigation covers issues in Immunology, Immunopathology, Hemophagocytic lymphohistiocytosis, Immune disorder and Pathogenesis.
Her Immunology research covers fields of interest such as STAT protein, HAVCR2 and Population.
Her STAT protein research includes elements of Ruxolitinib, Cytopenia, CD8, Janus kinase 1 and Myeloproliferative Disorders.
Geneviève de Saint Basile integrates several fields in her works, including HAVCR2, Immune system, T cell, T-cell lymphoma, Germline mutation and Subcutaneous Panniculitis-Like T-Cell Lymphoma.
Her specific area of interest is Immune system, where she studies Innate immune system.
The concepts of her Immune disorder study are interwoven with issues in Virus, CTL* and Lymphocytic choriomeningitis.
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