D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Microbiology D-index 60 Citations 13,033 128 World Ranking 2056 National Ranking 122

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • Immune system
  • Mutation

Cell biology, Immunology, Signal transduction, Molecular biology and X-linked lymphoproliferative disease are his primary areas of study. His study of SH3 domain is a part of Cell biology. His study in Immunology is interdisciplinary in nature, drawing from both Chronic mucocutaneous candidiasis and Mucocutaneous Candidiasis.

Sylvain Latour combines subjects such as Interleukin 12, CD47, Signal-regulatory protein alpha and IL-2 receptor with his study of Signal transduction. His Molecular biology research is multidisciplinary, incorporating elements of Tyrosine, Immunoreceptor tyrosine-based inhibitory motif, Receptor, Phosphorylation and Immunoglobulin E. His research in X-linked lymphoproliferative disease tackles topics such as Lymphoproliferative disorders which are related to areas like Cellular differentiation, Immune system, Pediatrics, Immune dysregulation and Survival rate.

His most cited work include:

  • XIAP deficiency in humans causes an X-linked lymphoproliferative syndrome (531 citations)
  • Efficacy of Gene Therapy for X-Linked Severe Combined Immunodeficiency (484 citations)
  • The same tyrosine-based inhibition motif, in the intra-cytoplasmic domain of FcγRIIB, regulates negatively BCR-, TCR-, and FcR-dependent cell activation (440 citations)

What are the main themes of his work throughout his whole career to date?

Sylvain Latour focuses on Immunology, Cell biology, Immune system, Immunodeficiency and Molecular biology. His work in the fields of Immunology, such as Natural killer T cell, Virus and Lymphoproliferative disorders, intersects with other areas such as XIAP. His Cell biology research is multidisciplinary, incorporating perspectives in Biochemistry and T-cell receptor.

His studies deal with areas such as NKG2D, X-linked lymphoproliferative disease and Lymphocyte as well as Immune system. His work carried out in the field of Immunodeficiency brings together such families of science as Cancer research, Primary immunodeficiency, Severe combined immunodeficiency and Immune dysregulation. His Molecular biology study combines topics in areas such as Cell culture, Transfection, Receptor, Immunoglobulin E and Gene product.

He most often published in these fields:

  • Immunology (57.14%)
  • Cell biology (33.57%)
  • Immune system (31.43%)

What were the highlights of his more recent work (between 2017-2021)?

  • Immune system (31.43%)
  • Cancer research (19.29%)
  • Immunology (57.14%)

In recent papers he was focusing on the following fields of study:

His primary areas of study are Immune system, Cancer research, Immunology, Epstein–Barr virus and T cell. Specifically, his work in Immune system is concerned with the study of Immunodeficiency. Sylvain Latour focuses mostly in the field of Immunodeficiency, narrowing it down to matters related to Cytokine and, in some cases, Cell biology, Mechanistic target of rapamycin, Phosphorylation and Autoimmune disease.

His study on Cancer research also encompasses disciplines like

  • Mutation that intertwine with fields like Kinase and MAPK/ERK pathway,
  • Germline mutation together with Carcinogenesis, Chromosomal translocation and Computational biology. His study in the fields of X-Linked Lymphoproliferative Syndrome under the domain of Epstein–Barr virus overlaps with other disciplines such as Molecular Diagnostic Method. His study focuses on the intersection of T cell and fields such as Lymphocyte with connections in the field of Acquired immune system and DOCK8 Deficiency.

Between 2017 and 2021, his most popular works were:

  • Dominant-negative IKZF1 mutations cause a T, B, and myeloid cell combined immunodeficiency (59 citations)
  • Inherited Immunodeficiencies With High Predisposition to Epstein-Barr Virus-Driven Lymphoproliferative Diseases. (40 citations)
  • Inherited Immunodeficiencies With High Predisposition to Epstein-Barr Virus-Driven Lymphoproliferative Diseases. (40 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • Immune system
  • Mutation

Sylvain Latour mostly deals with Epstein–Barr virus, Immune system, Lymphoproliferative disorders, Immunology and T cell. His Epstein–Barr virus study improves the overall literature in Virus. His biological study deals with issues like CD137, which deal with fields such as Primary immunodeficiency, T cell mediated immunity and Calcium flux.

His T cell research incorporates elements of Cancer research, Immunodeficiency, Mechanistic target of rapamycin, Phosphorylation and Lymphocyte. The Cancer research study combines topics in areas such as Mutation and Kinase, MAPK/ERK pathway, Kinase activity. The study incorporates disciplines such as Cytokine, Germline and Cell biology in addition to Immunodeficiency.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

XIAP deficiency in humans causes an X-linked lymphoproliferative syndrome

Stéphanie Rigaud;Marie-Claude Fondanèche;Nathalie Lambert;Nathalie Lambert;Benoit Pasquier.
Nature (2006)

718 Citations

Efficacy of Gene Therapy for X-Linked Severe Combined Immunodeficiency

Salima Hacein-Bey-Abina;Julia Hauer;Annick Lim;Capucine Picard.
The New England Journal of Medicine (2010)

688 Citations

Stepwise development of MAIT cells in mouse and human.

Emmanuel Martin;Emmanuel Treiner;Emmanuel Treiner;Livine Duban;Lucia Guerri.
PLOS Biology (2009)

550 Citations

The same tyrosine-based inhibition motif, in the intra-cytoplasmic domain of FcγRIIB, regulates negatively BCR-, TCR-, and FcR-dependent cell activation

Marc Daëron;Sylvain Latour;Odile Malbec;Eric Espinosa.
Immunity (1995)

526 Citations

The Syk Protein Tyrosine Kinase Is Essential for Fcγ Receptor Signaling in Macrophages and Neutrophils

Friedemann Kiefer;John Brumell;Nadia Al-Alawi;Sylvain Latour.
Molecular and Cellular Biology (1998)

455 Citations

Regulation of high-affinity IgE receptor-mediated mast cell activation by murine low-affinity IgG receptors.

M Daëron;O Malbec;S Latour;M Arock.
Journal of Clinical Investigation (1995)

408 Citations

Defective NKT cell development in mice and humans lacking the adapter SAP, the X-linked lymphoproliferative syndrome gene product

Benoit Pasquier;Luo Yin;Marie-Claude Fondanèche;Francis Relouzat.
Journal of Experimental Medicine (2005)

405 Citations

Munc18-2 deficiency causes familial hemophagocytic lymphohistiocytosis type 5 and impairs cytotoxic granule exocytosis in patient NK cells.

Marjorie Côte;Mickaël M. Ménager;Agathe Burgess;Nizar Mahlaoui.
Journal of Clinical Investigation (2009)

384 Citations

Impairment of immunity to Candida and Mycobacterium in humans with bi-allelic RORC mutations

Satoshi Okada;Satoshi Okada;Janet G Markle;Elissa K Deenick;Elissa K Deenick;Federico Mele.
Science (2015)

341 Citations

Clinical similarities and differences of patients with X-linked lymphoproliferative syndrome type 1 (XLP-1/SAP-deficiency) versus type 2 (XLP-2/XIAP-deficiency)

Jana Pachlopnik Schmid;Jana Pachlopnik Schmid;Danielle Canioni;Despina Moshous;Despina Moshous;Fabien Touzot.
Blood (2011)

340 Citations

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