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Sylvain Latour

Sylvain Latour

D-Index & Metrics

Microbiology

D-Index
67
Citations
15934
World Ranking
2275
National Ranking
130

Overview

Sylvain Latour is affiliated with the Institut Imagine in France. Their research primarily spans the fields of Medicine and Immunology and Microbiology, with extensive publication records in Immunology as a subfield. Other notable subfields include Epidemiology, Oncology, Molecular Biology, and Genetics.

Latour's scientific work is focused on multiple topics related to immune system function and disease mechanisms. These main topics include:

  • Immunodeficiency and Autoimmune Disorders
  • Immune Cell Function and Interaction
  • Cytomegalovirus and herpesvirus research
  • Viral-associated cancers and disorders
  • T-cell and B-cell Immunology
  • Biochemical and Molecular Research
  • Acute Lymphoblastic Leukemia research

Their frequent publication venues illustrate their engagement with leading journals in the field. Key venues with multiple publications include:

  • Blood
  • The Journal of Experimental Medicine
  • Journal of Clinical Immunology
  • Nature Communications
  • Journal of Allergy and Clinical Immunology

Latour has contributed to several research papers over recent years. Selected notable publications are:

  • "Primary immunodeficiencies reveal the molecular requirements for effective host defense against EBV infection," 2020, Blood
  • "HEM1 deficiency disrupts mTORC2 and F-actin control in inherited immunodysregulatory disease," 2020, Science
  • "Extended clinical and immunological phenotype and transplant outcome in CD27 and CD70 deficiency," 2020, Blood
  • "Contribution of rare and predicted pathogenic gene variants to childhood-onset lupus: a large, genetic panel analysis of British and French cohorts," 2020, The Lancet Rheumatology
  • "Human T-bet governs the generation of a distinct subset of CD11c high CD21 low B cells," 2022, Science Immunology

Regarding collaborations, Sylvain Latour frequently coauthors with several researchers, including:

  • David Boutboul
  • Emmanuel Martin
  • Benjamin Fournier
  • Capucine Pïcard
  • Alain Fischer

Best Publications

  • XIAP deficiency in humans causes an X-linked lymphoproliferative syndrome

    Stéphanie Rigaud;Marie-Claude Fondanèche;Nathalie Lambert;Nathalie Lambert;Benoit Pasquier

  • Efficacy of Gene Therapy for X-Linked Severe Combined Immunodeficiency

    Salima Hacein-Bey-Abina;Julia Hauer;Annick Lim;Capucine Picard

  • Stepwise development of MAIT cells in mouse and human.

    Emmanuel Martin;Emmanuel Treiner;Emmanuel Treiner;Livine Duban;Lucia Guerri

  • The same tyrosine-based inhibition motif, in the intra-cytoplasmic domain of FcγRIIB, regulates negatively BCR-, TCR-, and FcR-dependent cell activation

    Marc Daëron;Sylvain Latour;Odile Malbec;Eric Espinosa

  • The Syk Protein Tyrosine Kinase Is Essential for Fcγ Receptor Signaling in Macrophages and Neutrophils

    Friedemann Kiefer;John Brumell;Nadia Al-Alawi;Sylvain Latour

  • Clinical spectrum and features of activated phosphoinositide 3-kinase δ syndrome: A large patient cohort study.

    Tanya I Coulter;Anita Chandra;Chris M Bacon;Judith Babar

  • Impairment of immunity to Candida and Mycobacterium in humans with bi-allelic RORC mutations

    Satoshi Okada;Satoshi Okada;Janet G Markle;Elissa K Deenick;Elissa K Deenick;Federico Mele

  • Defective NKT cell development in mice and humans lacking the adapter SAP, the X-linked lymphoproliferative syndrome gene product

    Benoit Pasquier;Luo Yin;Marie-Claude Fondanèche;Francis Relouzat

  • Regulation of high-affinity IgE receptor-mediated mast cell activation by murine low-affinity IgG receptors.

    M Daëron;O Malbec;S Latour;M Arock

  • Munc18-2 deficiency causes familial hemophagocytic lymphohistiocytosis type 5 and impairs cytotoxic granule exocytosis in patient NK cells.

    Marjorie Côte;Mickaël M. Ménager;Agathe Burgess;Nizar Mahlaoui

  • Clinical similarities and differences of patients with X-linked lymphoproliferative syndrome type 1 (XLP-1/SAP-deficiency) versus type 2 (XLP-2/XIAP-deficiency)

    Jana Pachlopnik Schmid;Jana Pachlopnik Schmid;Danielle Canioni;Despina Moshous;Despina Moshous;Fabien Touzot

  • X-linked lymphoproliferative disease due to SAP/SH2D1A deficiency: a multicenter study on the manifestations, management, and outcome of the disease

    Claire Booth;Kimberly C. Gilmour;Paul Veys;Andrew R. Gennery

  • Binding of SAP SH2 domain to FynT SH3 domain reveals a novel mechanism of receptor signalling in immune regulation.

    Sylvain Latour;Romain Roncagalli;Riyan Chen;Marcin Bakinowski

  • Bidirectional negative regulation of human T and dendritic cells by CD47 and its cognate receptor signal-regulator protein-alpha: down-regulation of IL-12 responsiveness and inhibition of dendritic cell activation.

    Sylvain Latour;Hiroyuki Tanaka;Christian Demeure;Véronique Mateo

  • Regulation of SLAM-mediated signal transduction by SAP, the X-linked lymphoproliferative gene product

    Sylvain Latour;Sylvain Latour;Gerald Gish;Cheryl D. Helgason;R. Keith Humphries

  • NEGATIVE REGULATION OF IMMUNORECEPTOR SIGNALING

    André Veillette;Sylvain Latour;Dominique Davidson

  • High Expression of Inhibitory Receptor SHPS-1 and Its Association With Protein-Tyrosine Phosphatase SHP-1 in Macrophages

    André Veillette;Eric Thibaudeau;Sylvain Latour

  • Proximal protein tyrosine kinases in immunoreceptor signaling.

    Sylvain Latour;André Veillette

  • Differential Intrinsic Enzymatic Activity of Syk and Zap-70 Protein-tyrosine Kinases

    Sylvain Latour;Lionel M. L. Chow;André Veillette

  • CTP synthase 1 deficiency in humans reveals its central role in lymphocyte proliferation

    Emmanuel Martin;Noé Palmic;Sylvia Sanquer;Christelle Lenoir

  • Dok-3, a novel adapter molecule involved in the negative regulation of immunoreceptor signaling.

    Serge Lemay;Dominique Davidson;Sylvain Latour;André Veillette

Frequent Co-Authors

Alain Fischer
Alain Fischer Collège de France
Capucine Picard
Capucine Picard Université Paris Cité
André Veillette
André Veillette University of Montreal
Despina Moshous
Despina Moshous Necker-Enfants Malades Hospital
Wolf H. Fridman
Wolf H. Fridman Université Paris Cité
Frédéric Rieux-Laucat
Frédéric Rieux-Laucat Université Paris Cité
Jean-Pierre de Villartay
Jean-Pierre de Villartay Université Paris Cité
Marc Daëron
Marc Daëron Institut Pasteur
Frank M. Ruemmele
Frank M. Ruemmele Necker-Enfants Malades Hospital
Hirokazu Kanegane
Hirokazu Kanegane Tokyo Medical and Dental University

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