What is he best known for?
The fields of study he is best known for:
- Gene
- Cancer
- Internal medicine
His scientific interests lie mostly in Immunology, Genetic enhancement, Cell biology, Severe combined immunodeficiency and Transplantation.
His research investigates the link between Immunology and topics such as Stem cell that cross with problems in Embryonic stem cell.
Adrian J. Thrasher combines subjects such as Progenitor cell, Molecular biology, Viral vector and Transgene with his study of Genetic enhancement.
His biological study spans a wide range of topics, including Transduction and Virology.
The study incorporates disciplines such as Wiskott–Aldrich syndrome protein, Actin cytoskeleton, Arp2/3 complex, Wiskott–Aldrich syndrome and Retinitis pigmentosa in addition to Cell biology.
The concepts of his Severe combined immunodeficiency study are interwoven with issues in Insertional mutagenesis, Natural killer cell, Leukemia and Oncology.
His most cited work include:
- Effect of gene therapy on visual function in Leber's congenital amaurosis. (1589 citations)
- Correction of X-linked chronic granulomatous disease by gene therapy, augmented by insertional activation of MDS1-EVI1, PRDM16 or SETBP1. (1020 citations)
- Sustained Correction of X-Linked Severe Combined Immunodeficiency by ex Vivo Gene Therapy (977 citations)
What are the main themes of his work throughout his whole career to date?
Adrian J. Thrasher mostly deals with Immunology, Genetic enhancement, Cell biology, Viral vector and Stem cell.
His Immunology research includes elements of Wiskott–Aldrich syndrome and Transplantation.
His Genetic enhancement study incorporates themes from Haematopoiesis, Cancer research, Transgene, Virology and Severe combined immunodeficiency.
Adrian J. Thrasher has researched Haematopoiesis in several fields, including Progenitor cell, CD34 and Chronic granulomatous disease.
His Cell biology research is multidisciplinary, relying on both Wiskott–Aldrich syndrome protein, Podosome, Actin cytoskeleton and Cytoskeleton.
His Viral vector study combines topics from a wide range of disciplines, such as Molecular biology and Transduction.
He most often published in these fields:
- Immunology (48.12%)
- Genetic enhancement (43.99%)
- Cell biology (27.46%)
What were the highlights of his more recent work (between 2015-2021)?
- Genetic enhancement (43.99%)
- Immunology (48.12%)
- Cell biology (27.46%)
In recent papers he was focusing on the following fields of study:
Adrian J. Thrasher focuses on Genetic enhancement, Immunology, Cell biology, Haematopoiesis and Cancer research.
His Genetic enhancement study integrates concerns from other disciplines, such as CD34, Stem cell, Viral vector, Primary immunodeficiency and Transplantation.
His Immunology research includes themes of Hematopoietic stem cell transplantation, Wiskott–Aldrich syndrome and Severe combined immunodeficiency.
He focuses mostly in the field of Severe combined immunodeficiency, narrowing it down to topics relating to Common gamma chain and, in certain cases, Dendritic cell.
His work carried out in the field of Cell biology brings together such families of science as Cellular differentiation, T cell and Wiskott–Aldrich syndrome protein, Actin cytoskeleton, Cytoskeleton.
The various areas that Adrian J. Thrasher examines in his Haematopoiesis study include Progenitor cell, Homing and Chronic granulomatous disease.
Between 2015 and 2021, his most popular works were:
- Molecular remission of infant B-ALL after infusion of universal TALEN gene-edited CAR T cells (444 citations)
- Hematopoietic Stem-Cell Gene Therapy for Cerebral Adrenoleukodystrophy (189 citations)
- The European Society for Immunodeficiencies (ESID) Registry Working Definitions for the Clinical Diagnosis of Inborn Errors of Immunity (123 citations)
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