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Immunology

D-Index
42
Citations
6129
World Ranking
4899
National Ranking
411

Overview

Austen Worth is affiliated with Great Ormond Street Hospital in the United Kingdom. Their research spans multiple fields within medicine, with a focus on immunology and microbiology.

Their work concentrates on several subfields, including immunology, genetics, epidemiology, hematology, and oncology. The main topics addressed in their publications include immunodeficiency and autoimmune disorders, blood disorders and treatments, cytomegalovirus and herpesvirus research, hematopoietic stem cell transplantation, immune cell function and interaction, autoimmune and inflammatory disorders research, and genomics and rare diseases.

Austen Worth has contributed to numerous papers. Significant recent publications include:

  • Phage Therapy of Mycobacterium Infections: Compassionate Use of Phages in 20 Patients With Drug-Resistant Mycobacterial Disease (2022), published in Clinical Infectious Diseases
  • Whole-genome sequencing of a sporadic primary immunodeficiency cohort (2020), published in Nature
  • Hematopoietic cell transplantation in severe combined immunodeficiency: The SCETIDE 2006-2014 European cohort (2021), published in Journal of Allergy and Clinical Immunology
  • Extended clinical and immunological phenotype and transplant outcome in CD27 and CD70 deficiency (2020), published in Blood
  • Neuroinflammatory Disease as an Isolated Manifestation of Hemophagocytic Lymphohistiocytosis (2020), published in Journal of Clinical Immunology

Frequent coauthors collaborating with Austen Worth include Kanchan Rao, Judith Breuer, Claire Booth, Andrew R. Gennery, and Alexandra Y. Kreins.

Their research is often published in venues such as the Journal of Clinical Immunology, bioRxiv (Cold Spring Harbor Laboratory), Journal of Allergy and Clinical Immunology, Blood, and Clinical Immunology.

Best Publications

  • The extended phenotype of LPS-responsive beige-like anchor protein (LRBA) deficiency

    Laura Gámez-Díaz;Dietrich August;Polina Stepensky;Shoshana Revel-Vilk

  • Long-term follow-up of IPEX syndrome patients after different therapeutic strategies: An international multicenter retrospective study

    Federica Barzaghi;Laura Cristina Amaya Hernandez;Benedicte Neven;Silvia Ricci

  • Two novel activating mutations in the Wiskott-Aldrich syndrome protein result in congenital neutropenia

    Phil J. Ancliff;Michael P. Blundell;Giles O. Cory;Yolanda Calle

  • Whole-genome sequencing of a sporadic primary immunodeficiency cohort

    Thaventhiran Jed.;H Lango Allen;O S Burren;W Rae

  • Loss-of-function nuclear factor κB subunit 1 (NFKB1) variants are the most common monogenic cause of common variable immunodeficiency in Europeans

    Paul Tuijnenburg;Hana Lango Allen;Hana Lango Allen;Siobhan O. Burns;Daniel Greene;Daniel Greene

  • Autoimmune lymphoproliferative syndrome: molecular basis of disease and clinical phenotype.

    Austen Worth;Adrian J. Thrasher;Adrian J. Thrasher;H. Bobby Gaspar;H. Bobby Gaspar

  • Omission of in vivo T-cell depletion promotes rapid expansion of naïve CD4+ cord blood lymphocytes and restores adaptive immunity within 2 months after unrelated cord blood transplant.

    Robert Chiesa;Kimberly Gilmour;Waseem Qasim;Stuart Adams

  • Long-term outcome of LRBA deficiency in 76 patients after various treatment modalities as evaluated by the immune deficiency and dysregulation activity (IDDA) score

    Victoria Katharina Tesch;Hassan Abolhassani;Hassan Abolhassani;Bella Shadur;Bella Shadur;Joachim Zobel

  • WIP Regulates the Stability and Localization of WASP to Podosomes in Migrating Dendritic Cells

    Hsiu-Chuan Chou;Inés M. Antón;Mark R. Holt;Claudia Curcio

  • T-cell receptor αβ+ and CD19+ cell–depleted haploidentical and mismatched hematopoietic stem cell transplantation in primary immune deficiency

    Ravi M. Shah;Reem Elfeky;Zohreh Nademi;Waseem Qasim

  • Thymus Transplantation for Complete Digeorge Syndrome: European Experience

    E. Graham Davies;E. Graham Davies;Melissa Cheung;Kimberly Gilmour;Jesmeen Maimaris

  • The Wiskott-Aldrich Syndrome: The Actin Cytoskeleton and Immune Cell Function

    Michael P. Blundell;Austen Worth;Gerben Bouma;Adrian J. Thrasher

  • Inherited p40phox deficiency differs from classic chronic granulomatous disease

    Annemarie Van De Geer;Alejandro Nieto-Patlán;Alejandro Nieto-Patlán;Alejandro Nieto-Patlán;Douglas B. Kuhns;Anton T.J. Tool

  • Risk factors predisposing to the development of hypogammaglobulinemia and infections post-Rituximab.

    Evangelos A A Christou;Giuliana Giardino;Austen Worth;Fani Ladomenou

  • Human cytomegalovirus haplotype reconstruction reveals high diversity due to superinfection and evidence of within-host recombination.

    Juliana Cudini;Sunando Roy;Charlotte J. Houldcroft;Josephine M. Bryant

  • Pre-emptive rituximab based on viraemia and T cell reconstitution: a highly effective strategy for the prevention of Epstein-Barr virus-associated lymphoproliferative disease following stem cell transplantation.

    Austen Worth;Austen Worth;Rachel Conyers;Jonathon Cohen;Mamta Jagani

  • Identifying functional defects in patients with immune dysregulation due to LRBA and CTLA-4 mutations

    Tie Zheng Hou;Nisha Verma;Jennifer Wanders;Alan Kennedy

  • Treosulfan and Fludarabine Conditioning for Hematopoietic Stem Cell Transplantation in Children with Primary Immunodeficiency: UK Experience

    Mary A. Slatter;Kanchan Rao;Intan Juliana Abd Hamid;Intan Juliana Abd Hamid;Zohreh Nademi

  • Characterization of the clinical and immunologic phenotype and management of 157 individuals with 56 distinct heterozygous NFKB1 mutations

    Tiziana Lorenzini;Manfred Fliegauf;Nils Klammer;Natalie Frede

  • Hematopoietic cell transplantation in severe combined immunodeficiency: The SCETIDE 2006-2014 European cohort.

    Arjan C. Lankester;Benedicte Neven;Nizar Mahlaoui;Erik G.J. von Asmuth

  • A new functional assay for the diagnosis of X-linked inhibitor of apoptosis (XIAP) deficiency.

    S. Ammann;S. Ammann;R. Elling;M. Gyrd-Hansen;G. Dückers

  • Extended clinical and immunological phenotype and transplant outcome in CD27 and CD70 deficiency

    Sujal Ghosh;Sevgi Köstel Bal;Sevgi Köstel Bal;Emily S.J. Edwards;Emily S.J. Edwards;Bethany Pillay;Bethany Pillay

Frequent Co-Authors

Adrian J. Thrasher
Adrian J. Thrasher University College London
Siobhan O. Burns
Siobhan O. Burns University College London
Persis Amrolia
Persis Amrolia Great Ormond Street Hospital
Paul Veys
Paul Veys Great Ormond Street Hospital
Andrew R. Gennery
Andrew R. Gennery Newcastle University
Mary Slatter
Mary Slatter Newcastle University
Kimberly Gilmour
Kimberly Gilmour Great Ormond Street Hospital
Judith Breuer
Judith Breuer University College London
Andrew J. Cant
Andrew J. Cant Newcastle University
Sophie Hambleton
Sophie Hambleton Newcastle University

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