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Immunology

D-Index
111
Citations
42106
World Ranking
481
National Ranking
292

Research.com Recognitions

  • 2010 - Fellow of the American Association for the Advancement of Science (AAAS)

Overview

Cox Terhorst is affiliated with the Beth Israel Deaconess Medical Center in the United States. Their research primarily spans the fields of Biochemistry, Genetics and Molecular Biology, and Medicine, with a particular focus on Genetics, Oncology, and Molecular Biology as subfields. The scientist's work also touches on Hematology and Epidemiology.

The main topics addressed in Terhorst's research include virus-based gene therapy, CAR-T cell therapy, RNA interference and gene delivery, hemophilia treatment, viral infectious diseases and gene expression in insects, cytomegalovirus and herpesvirus research, and viral gastroenteritis epidemiology.

Terhorst has contributed to several research articles, including:

  • Immune Responses to Viral Gene Therapy Vectors, 2020, published in Molecular Therapy
  • IL-15 blockade and rapamycin rescue multifactorial loss of factor VIII from AAV-transduced hepatocytes in hemophilia A mice, 2022, published in Molecular Therapy
  • B cell focused transient immune suppression protocol for efficient AAV readministration to the liver, 2024, published in Molecular Therapy - Methods & Clinical Development
  • TLR9-Independent CD8 T Cell Responses in Hepatic AAV Gene Transfer Through IL-1R1-MyD88 Signaling, 2023, published in SSRN Electronic Journal

The scientist has frequently published in venues such as Molecular Therapy, Molecular Therapy - Methods & Clinical Development, and SSRN Electronic Journal.

Frequent collaborators include Roland W. Herzog, Ype P. de Jong, Moanaro Biswas, Kentaro Yamada, and Sandeep Kumar.

Terhorst was named a Fellow of the American Association for the Advancement of Science (AAAS) in 2010.

Best Publications

  • SLAM Family Receptors Distinguish Hematopoietic Stem and Progenitor Cells and Reveal Endothelial Niches for Stem Cells

    Mark J. Kiel;Ömer H. Yilmaz;Toshihide Iwashita;Osman H. Yilmaz

  • The X-linked lymphoproliferative-disease gene product SAP regulates signals induced through the co-receptor SLAM

    J. Sayos;C. Wu;M. Morra;N. Wang

  • The T Cell Receptor/CD3 Complex: A Dynamic Protein Ensemble

    Hans Clevers;Balbino Alarcon;Thomas Wileman;Cox Terhorst

  • The Role of the T3/Antigen Receptor Complex in T-Cell Activation

    Arthur Weiss;John Imboden;Kenneth Hardy;Bernhard Manger

  • Immune Responses to Viral Gene Therapy Vectors.

    Jamie L. Shirley;Ype P. de Jong;Cox Terhorst;Roland W. Herzog

  • Recognition of cluster of differentiation 1 antigens by human CD4 − CD8 >− cytolytic T lymphocyte

    Steven Porcelli;Steven Porcelli;Michael B. Brenner;Michael B. Brenner;Julia L. Greenstein;Cox Terhorst

  • Requirement for natural killer cell-produced interferon gamma in defense against murine cytomegalovirus infection and enhancement of this defense pathway by interleukin 12 administration.

    Jordan S. Orange;Baoping Wang;Cox Terhorst;Christine A. Biron

  • Sequence and expression of transcripts of the human T-cell receptor β-chain genes

    Yasunobu Yoshikai;Demetri Anatoniou;Stephen P. Clark;Yusuke Yanagi

  • Characterization of a human B cell-specific antigen (B2) distinct from B1.

    L M Nadler;P Stashenko;R Hardy;A van Agthoven

  • Homotypic Interactions Mediated by Slamf1 and Slamf6 Receptors Control NKT Cell Lineage Development

    Klaus Griewank;Christine Borowski;Svend Rietdijk;Ninghai Wang

  • T Cell–mediated Pathology in Two Models of Experimental Colitis Depends Predominantly on the Interleukin 12/Signal Transducer and Activator of Transcription (Stat)-4 Pathway, but Is Not Conditional on Interferon γ Expression by T Cells

    Stephen J. Simpson;Samir Shah;Martina Comiskey;Ype P. de Jong

  • Reconstitution of an active surface T3/T-cell antigen receptor by DNA transfer

    Pamela S. Ohashi;Tak W. Mak;Peter Van den Elsen;Yusuke Yanagi

  • The SAP and SLAM families in immune responses and X-linked lymphoproliferative disease.

    Pablo Engel;Michael J. Eck;Cox Terhorst

  • SAP couples Fyn to SLAM immune receptors.

    Betty Liwah Chan;Arpad Lanyi;Arpad Lanyi;Hyun Kyu Song;Jan Griesbach

  • Development of chronic colitis is dependent on the cytokine MIF

    Y. P. de Jong;A. C. Abadia-Molina;A. R. Satoskar;K. Clarke

  • Stimulation of the T3-T cell receptor complex induces a membrane-potential-sensitive calcium influx.

    Hans C. Oettgen;Cox Terhorst;Lewis C. Cantley;Philip M. Rosoff

  • SAP controls T cell responses to virus and terminal differentiation of TH2 cells.

    Chengbin Wu;Khuong B. Nguyen;Gary C. Pien;Ninghai Wang

  • Biochemical studies of the human thymocyte cell-surface antigens T6, T9 and T10.

    Cox Terhorst;Andre van Agthoven;Kenneth Leclair;Peter Snow

  • Developmental control point in induction of thymic cortex regulated by a subpopulation of prothymocytes

    G. A. Holländer;Baoping Wang;A. Nichogiannopoulou;P. P. Platenburg

  • Expression of murine CD1 on gastrointestinal epithelium.

    Paul A. Bleicher;Steven P. Balk;Steven P. Balk;Susan J. Hagen;Richard S. Blumberg;Richard S. Blumberg

  • Characteristics of a monoclonal antibody (WT-31) that recognizes a common epitope on the human T cell receptor for antigen.

    H. Spits;J. Borst;W. Tax;P. J. A. Capel

  • T cells as therapeutic targets in SLE

    José C. Crispín;Vasileios C. Kyttaris;Cox Terhorst;George C. Tsokos

Frequent Co-Authors

Atul K. Bhan
Atul K. Bhan Harvard University
Roland W. Herzog
Roland W. Herzog Indiana University
Jaime Sancho
Jaime Sancho Spanish National Research Council
Pablo Engel
Pablo Engel University of Barcelona
Emiko Mizoguchi
Emiko Mizoguchi Kurume University
Jack L. Strominger
Jack L. Strominger Harvard University
George C. Tsokos
George C. Tsokos Harvard Medical School
Hans C. Oettgen
Hans C. Oettgen Boston Children's Hospital
Jannie Borst
Jannie Borst Leiden University Medical Center
Arlene H. Sharpe
Arlene H. Sharpe Harvard University

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