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Immunology

D-Index
67
Citations
16308
World Ranking
2666
National Ranking
1276

Overview

Hans C. Oettgen is affiliated with Boston Children's Hospital in the United States. Their research extensively covers the fields of Medicine and Immunology and Microbiology, with a particular focus on immunology-related subfields.

The primary subfields of their work include Immunology, Immunology and Allergy, Physiology, Infectious Diseases, and Pediatrics, Perinatology and Child Health. Their publications focus on several main topics such as Food Allergy and Anaphylaxis Research, Mast cells and histamine, Asthma and respiratory diseases, Allergic Rhinitis and Sensitization, Immunodeficiency and Autoimmune Disorders, IL-33, ST2, and ILC Pathways, and T-cell and B-cell Immunology.

The scientist has published in multiple venues, with frequent contributions to:

  • Journal of Allergy and Clinical Immunology
  • Immunity
  • Frontiers in Immunology
  • Contemporary Clinical Trials
  • Cell Reports Medicine

Recent papers authored or co-authored by Hans C. Oettgen include:

  • "IgE and IgG Antibodies as Regulators of Mast Cell and Basophil Functions in Food Allergy" (2020, Frontiers in Immunology)
  • "Regulatory T Cell-Derived TGF-β1 Controls Multiple Checkpoints Governing Allergy and Autoimmunity" (2020, Immunity)
  • "Preventing asthma in high risk kids (PARK) with omalizumab: Design, rationale, methods, lessons learned and adaptation" (2020, Contemporary Clinical Trials)
  • "High-resolution epitope mapping by AllerScan reveals relationships between IgE and IgG repertoires during peanut oral immunotherapy" (2021, Cell Reports Medicine)
  • "Mast cells in food allergy: Inducing immediate reactions and shaping long-term immunity" (2022, Journal of Allergy and Clinical Immunology)

Frequent co-authors collaborating with Hans C. Oettgen include:

  • Wanda Phipatanakul
  • Janet Chou
  • Harald Renz
  • Raif S. Geha
  • Zuhair K. Ballas

Best Publications

  • The X-linked lymphoproliferative-disease gene product SAP regulates signals induced through the co-receptor SLAM

    J. Sayos;C. Wu;M. Morra;N. Wang

  • Adaptive immunity

    Unknown

  • IgE Enhances Mouse Mast Cell FcεRI Expression In Vitro and In Vivo: Evidence for a Novel Amplification Mechanism in IgE-dependent Reactions

    Masao Yamaguchi;Chris S. Lantz;Hans C. Oettgen;Ildy M. Katona

  • Allergen-Induced Bronchial Hyperreactivity and Eosinophilic Inflammation Occur in the Absence of IgE in a Mouse Model of Asthma

    Paul D. Mehlhop;Matthijs van de Rijn;Alison B. Goldberg;Joanne P. Brewer

  • A microbiota signature associated with experimental food allergy promotes allergic sensitization and anaphylaxis

    Magali Noval Rivas;Oliver T. Burton;Petra Wise;Yu-qian Zhang

  • Active anaphylaxis in IgE-deficient mice

    Hans C. Oettgen;Thomas R. Martin;Thomas R. Martin;Anthony Wynshaw-Boris;Chuxia Deng

  • Roles of TH1 and TH2 cytokines in a murine model of allergic dermatitis

    Jonathan M. Spergel;Emiko Mizoguchi;Hans Oettgen;Atul K. Bhan

  • Food allergy

    Unknown

  • Regulatory T cell reprogramming toward a Th2-cell-like lineage impairs oral tolerance and promotes food allergy.

    Magali Noval Rivas;Magali Noval Rivas;Oliver T. Burton;Oliver T. Burton;Petra Wise;Louis-Marie Charbonnier;Louis-Marie Charbonnier

  • Stimulation of the T3-T cell receptor complex induces a membrane-potential-sensitive calcium influx.

    Hans C. Oettgen;Cox Terhorst;Lewis C. Cantley;Philip M. Rosoff

  • CCR3 is essential for skin eosinophilia and airway hyperresponsiveness in a murine model of allergic skin inflammation

    Weilie Ma;Paul J. Bryce;Alison A. Humbles;Dhafer Laouini

  • IgE regulation and roles in asthma pathogenesis

    Hans C. Oettgen;Raif S. Geha

  • A T3-like protein complex associated with the antigen receptor on murine T cells

    Oettgen Hc;Pettey Cl;Maloy Wl;Terhorst C

  • Eotaxin triggers eosinophil-selective chemotaxis and calcium flux via a distinct receptor and induces pulmonary eosinophilia in the presence of interleukin 5 in mice.

    M. E. Rothenberg;R. Ownbey;P. D. Mehlhop;P. M. Loiselle

  • IgE in asthma and atopy: cellular and molecular connections

    Hans C. Oettgen;Raif S. Geha

  • IL-4 production by group 2 innate lymphoid cells promotes food allergy by blocking regulatory T-cell function

    Magali Noval Rivas;Magali Noval Rivas;Oliver T. Burton;Oliver T. Burton;Hans C. Oettgen;Hans C. Oettgen;Talal Chatila;Talal Chatila

  • IgE enhances parasite clearance and regulates mast cell responses in mice infected with Trichinella spiralis.

    Michael F. Gurish;Paul J. Bryce;Hong Tao;Alison B. Kisselgof

  • Immune sensitization in the skin is enhanced by antigen-independent effects of IgE.

    Paul J Bryce;Mendy L Miller;Ichiro Miyajima;Mindy Tsai

  • Molecular and Biological Characterization of the Murine Leukotriene B4 Receptor Expressed on Eosinophils

    Wei-Wei Huang;Eduardo A. Garcia-Zepeda;Alain Sauty;Hans C. Oettgen

  • SLP-76 deficiency impairs signaling via the high-affinity IgE receptor in mast cells.

    Vadim I. Pivniouk;Thomas R. Martin;Jennifer M. Lu-Kuo;Howard R. Katz

  • IL-10 is critical for Th2 responses in a murine model of allergic dermatitis

    Dhafer Laouini;Harri Alenius;Paul Bryce;Hans Oettgen

  • IgE regulates mouse basophil Fc epsilon RI expression in vivo.

    C S Lantz;M Yamaguchi;H C Oettgen;I M Katona

Frequent Co-Authors

Raif S. Geha
Raif S. Geha Boston Children's Hospital
Talal A. Chatila
Talal A. Chatila Boston Children's Hospital
Cox Terhorst
Cox Terhorst Beth Israel Deaconess Medical Center
Michael F. Gurish
Michael F. Gurish Harvard Medical School
Stephen J. Galli
Stephen J. Galli Stanford University
Lynda C. Schneider
Lynda C. Schneider Boston Children's Hospital
Paul J. Bryce
Paul J. Bryce University of Massachusetts Lowell
Dale T. Umetsu
Dale T. Umetsu Stanford University
Daniel S. Friend
Daniel S. Friend Brigham and Women's Hospital
Edda Fiebiger
Edda Fiebiger Boston Children's Hospital

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