World's Best Scientists 2026 revealed!

D-Index & Metrics

Biology and Biochemistry

D-Index
77
Citations
23837
World Ranking
4732
National Ranking
2291

Overview

Elisabeth A. Seftor is affiliated with Northwestern University in the United States, contributing to the fields of biochemistry, genetics, and molecular biology. Their research primarily spans cell biology, molecular biology, immunology, and organic chemistry.

Their recent publications include notable works such as:

  • Experimental coexpression of vimentin and keratin intermediate filaments in human melanoma cells augments motility., 2020, PubMed
  • CVM-1118 (foslinanib), a 2-phenyl-4-quinolone derivative, promotes apoptosis and inhibits vasculogenic mimicry via targeting TRAP1, 2023, Pathology & Oncology Research
  • Editor's Note: The Paradoxical Expression of Maspin in Ovarian Carcinoma, 2021, Clinical Cancer Research
  • Correction: Margaryan et al. The Stem Cell Phenotype of Aggressive Breast Cancer Cells. Cancers 2019, 11, 340, 2025, Cancers

Their frequent co-authors include Mary J.C. Hendrix, Richard E.B. Seftor, Yi Wen Chu, Lewis H. Romer, and Lifen Shen.

Publication venues where Elisabeth A. Seftor has contributed include:

  • PubMed
  • Pathology & Oncology Research
  • Clinical Cancer Research
  • Cancers

The main scientific domains of their research are within biochemistry, genetics, and molecular biology, focusing in particular on the subfields of cell biology, molecular biology, immunology and allergy, organic chemistry, and immunology.

Key topics addressed in their work are:

  • Skin and Cellular Biology Research
  • Cellular Mechanics and Interactions
  • Cell Adhesion Molecules Research
  • Quinazolinone synthesis and applications
  • Histone Deacetylase Inhibitors Research
  • Phytochemical compounds biological activities
  • Signaling Pathways in Disease

The scientist's research outputs emphasize mechanisms affecting cellular motility, apoptotic regulation, and cancer cell behavior, engaging with molecular pathways relevant to disease and therapeutic development.

Best Publications

  • Vascular Channel Formation by Human Melanoma Cells in Vivo and in Vitro: Vasculogenic Mimicry

    Andrew J. Maniotis;Robert Folberg;Angela Hess;Elisabeth A. Seftor

  • Maspin, a serpin with tumor-suppressing activity in human mammary epithelial cells

    Zhiqiang Zou;Anthony Anisowicz;Mary J. C. Hendrix;Ann Thor

  • Acidic pH enhances the invasive behavior of human melanoma cells.

    Raul Martínez-Zaguilán;Elisabeth A. Seftor;Richard E B Seftor;Yi Wen Chu

  • Expression and functional significance of VE-cadherin in aggressive human melanoma cells: role in vasculogenic mimicry

    Mary J. C. Hendrix;Elisabeth A. Seftor;Paul S. Meltzer;Lynn M. G. Gardner

  • Role of the alpha v beta 3 integrin in human melanoma cell invasion.

    Richard E. B. Seftor;Elisabeth A. Seftor;Kurt R. Gehlsen;William G. Stetler-Stevenson

  • Reprogramming metastatic tumour cells with embryonic microenvironments.

    Mary J.C. Hendrix;Elisabeth A. Seftor;Richard E.B. Seftor;Jennifer Kasemeier-Kulesa

  • Maspin acts at the cell membrane to inhibit invasion and motility of mammary and prostatic cancer cells

    Shijie Sheng;Juliana Carey;Elisabeth A. Seftor;Lauren Dias

  • Cooperative interactions of laminin 5 gamma2 chain, matrix metalloproteinase-2, and membrane type-1-matrix/metalloproteinase are required for mimicry of embryonic vasculogenesis by aggressive melanoma.

    Richard E. B. Seftor;Elisabeth A. Seftor;Naohiko Koshikawa;Paul S. Meltzer

  • The use of nuclear-encoded sequences to direct the light-regulated synthesis and transport of a foreign protein into plant chloroplasts.

    Peter H. Schreier;Elisabeth A. Seftor;Jozef Schell;Hans J. Bohnert;Hans J. Bohnert

  • Experimental co-expression of vimentin and keratin intermediate filaments in human breast cancer cells results in phenotypic interconversion and increased invasive behavior

    Mary J.C. Hendrix;Elisabeth A. Seftor;Richard E.B. Seftor;Katrina T. Trevor

  • Molecular Regulation of Tumor Cell Vasculogenic Mimicry by Tyrosine Phosphorylation: Role of Epithelial Cell Kinase (Eck/EphA2)

    Angela R. Hess;Elisabeth A. Seftor;Lynn M. G. Gardner;Kelly Carles-Kinch

  • The fate of human malignant melanoma cells transplanted into zebrafish embryos: assessment of migration and cell division in the absence of tumor formation.

    Lisa M.J. Lee;Lisa M.J. Lee;Elisabeth A. Seftor;Gregory Bonde;Robert A. Cornell

  • Role of intermediate filaments in migration, invasion and metastasis

    Mary J. C. Hendrix;Elisabeth A. Seftor;Yi-Wen Chu;Katrina T. Trevor

  • Molecular determinants of ovarian cancer plasticity.

    Anil K. Sood;Elisabeth A. Seftor;Mavis S. Fletcher;Lynn M.G. Gardner

  • Human embryonic stem cell microenvironment suppresses the tumorigenic phenotype of aggressive cancer cells

    Lynne Marie Postovit;Naira V. Margaryan;Elisabeth A. Seftor;Dawn A. Kirschmann

  • Lysyl Oxidase Regulates Breast Cancer Cell Migration and Adhesion through a Hydrogen Peroxide–Mediated Mechanism

    Stacey L. Payne;Ben Fogelgren;Angela R. Hess;Elisabeth A. Seftor

  • Reprogramming metastatic melanoma cells to assume a neural crest cell-like phenotype in an embryonic microenvironment

    Paul M. Kulesa;Jennifer C. Kasemeier-Kulesa;Jessica M. Teddy;Naira V. Margaryan

  • Tumor Cell Vasculogenic Mimicry: From Controversy to Therapeutic Promise

    Richard E.B. Seftor;Angela R. Hess;Elisabeth A. Seftor;Dawn A. Kirschmann

  • Molecular Pathways: Vasculogenic Mimicry in Tumor Cells: Diagnostic and Therapeutic Implications

    Dawn A. Kirschmann;Elisabeth A. Seftor;Katharine M. Hardy;Richard E.B. Seftor

  • Effects of Angiogenesis Inhibitors on Vascular Network Formation by Human Endothelial and Melanoma Cells

    Daisy W. J. van der Schaft;Richard E. B. Seftor;Elisabeth A. Seftor;Angela R. Hess

Frequent Co-Authors

Mary J.C. Hendrix
Mary J.C. Hendrix Northwestern University
Paul S. Meltzer
Paul S. Meltzer National Institutes of Health
Jeffrey M. Trent
Jeffrey M. Trent Translational Genomics Research Institute
Marcelo B. Soares
Marcelo B. Soares University of Illinois at Peoria
Brian J. Nickoloff
Brian J. Nickoloff Loyola University Chicago
William G. Stetler-Stevenson
William G. Stetler-Stevenson National Institutes of Health
Cynthia J. Meininger
Cynthia J. Meininger Texas A&M University
Danny R. Welch
Danny R. Welch University of Kansas
Ruth Sager
Ruth Sager Harvard University
Guoyao Wu
Guoyao Wu Texas A&M University

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