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Phillip I. Bird

Phillip I. Bird

D-Index & Metrics

Molecular Biology

D-Index
63
Citations
13052
World Ranking
1811
National Ranking
44

Overview

Phillip I. Bird is affiliated with Monash University in Australia. Their research spans multiple disciplines, primarily focusing on biochemistry, genetics, molecular biology, medicine, and immunology and microbiology. The scientist has contributed extensively to subfields such as molecular biology, immunology, sensory systems, immunology and allergy, and neurology.

Their work covers key topics including:

  • Hearing, cochlea, tinnitus, genetics
  • Immune response and inflammation
  • RNA interference and gene delivery
  • Vestibular and auditory disorders
  • Hearing loss and rehabilitation
  • Immune cell function and interaction
  • Advanced biosensing and bioanalysis techniques

Notable recent papers include:

  • "Extracellular Granzyme A Promotes Colorectal Cancer Development by Enhancing Gut Inflammation" (2020, Cell Reports)
  • "The Serpins Are an Expanding Superfamily of Structurally Similar but Functionally Diverse Proteins: EVOLUTION, MECHANISM OF INHIBITION, NOVEL FUNCTIONS, AND A REVISED NOMENCLATURE" (2021, UNC Libraries)
  • "Granzyme A inhibition reduces inflammation and increases survival during abdominal sepsis" (2021, Theranostics)
  • "Granzyme A in Chikungunya and Other Arboviral Infections" (2020, Frontiers in Immunology)
  • "Noninvasive optical detection of granzyme B from natural killer cells with enzyme-activated fluorogenic probes" (2020, Journal of Biological Chemistry)

Frequent co-authors in Phillip I. Bird's research include Dion Kaiserman, Llipsy Santiago, Ariel Ramírez-Labrada, Elena Tapia, and Iratxe Uranga-Murillo. These collaborations indicate ongoing research networks and shared interests in related fields.

Phillip I. Bird's publications often appear in journals such as Theranostics, Journal of Biological Chemistry, bioRxiv (Cold Spring Harbor Laboratory), Journal of Genetics and Genomics, and Otology & Neurotology, reflecting a diverse publication portfolio spanning both clinical and molecular research.

Best Publications

  • The serpins are an expanding superfamily of structurally similar but functionally diverse proteins - Evolution, mechanism of inhibition, novel functions, and a revised nomenclature

    Gary A. Silverman;Phillip I. Bird;Robin W. Carrell;Frank C. Church

  • An overview of the serpin superfamily

    Ruby H P Law;Qingwei Zhang;Sheena McGowan;Ashley Maurice Buckle

  • The structural basis for membrane binding and pore formation by lymphocyte perforin

    Ruby H P Law;Natalya Lukoyanova;Ilia Voskoboinik;Ilia Voskoboinik;Tom T Caradoc-Davies

  • A Cytosolic Granzyme B Inhibitor Related to the Viral Apoptotic Regulator Cytokine Response Modifier A Is Present in Cytotoxic Lymphocytes

    Jiuru Sun;Catherina H. Bird;Vivien Sutton;Lisa McDonald

  • A Common Fold Mediates Vertebrate Defense and Bacterial Attack

    Carlos J. Rosado;Ashley M. Buckle;Ruby H. P. Law;Rebecca E. Butcher;Rebecca E. Butcher

  • The MACPF/CDC family of pore-forming toxins.

    Carlos Joaquim Rosado;Stephanie Kondos;Tara Elaina Bull;Michael Kuiper

  • Extracellular matrix remodeling by human granzyme B via cleavage of vitronectin, fibronectin, and laminin

    Marguerite S. Buzza;Laura Zamurs;Jiuru Sun;Catherina H. Bird

  • Perforin forms transient pores on the target cell plasma membrane to facilitate rapid access of granzymes during killer cell attack

    Jamie Lopez;Jamie Lopez;Olivia Susanto;Misty Jenkins;Misty Jenkins;Natalya Lukoyanova

  • Selective Regulation of Apoptosis: the Cytotoxic Lymphocyte Serpin Proteinase Inhibitor 9 Protects against Granzyme B-Mediated Apoptosis without Perturbing the Fas Cell Death Pathway

    Catherina H. Bird;Vivien R. Sutton;Jiuru Sun;Claire E. Hirst

  • The intracellular granzyme B inhibitor, proteinase inhibitor 9, is up-regulated during accessory cell maturation and effector cell degranulation, and its overexpression enhances CTL potency.

    Claire E Hirst;Marguerite Stella Buzza;Catherina Hedwig Bird;Hilary S Warren

  • The major human and mouse granzymes are structurally and functionally divergent

    Dion Kaiserman;Catherina Hedwig Bird;Jiuru Sun;Antony Yaron Matthews

  • Cathepsin G Inhibition by Serpinb1 and Serpinb6 Prevents Programmed Necrosis in Neutrophils and Monocytes and Reduces GSDMD-Driven Inflammation.

    Sabrina Sofia Burgener;Nathan Georges François Leborgne;Scott J. Snipas;Guy S. Salvesen

  • Human clade B serpins (ov-serpins) belong to a cohort of evolutionarily dispersed intracellular proteinase inhibitor clades that protect cells from promiscuous proteolysis.

    Gary A Silverman;James C Whisstock;D J Askew;Stephen C Pak

  • Endolysosomal proteases and their inhibitors in immunity

    Phillip Ian Bird;Joseph A Trapani;Jose A Villadangos

  • Extracellular granzymes: current perspectives.

    Marguerite Stella Buzza;Phillip Ian Bird

  • A central role for Bid in granzyme B-induced apoptosis

    Nigel J Waterhouse;Karin A Sedelies;Kylie A Browne;Michelle E Wowk

  • Serpins flex their muscle: I. Putting the clamps on proteolysis in diverse biological systems.

    Gary A Silverman;James C Whisstock;Stephen Paul Bottomley;James A Huntington

  • Nucleocytoplasmic distribution of the ovalbumin serpin PI-9 requires a nonconventional nuclear import pathway and the export factor Crm1.

    Catherina H. Bird;Elizabeth J. Blink;Claire E. Hirst;Marguerite S. Buzza

  • A New Family of 10 Murine Ovalbumin Serpins Includes Two Homologs of Proteinase Inhibitor 8 and Two Homologs of the Granzyme B Inhibitor (Proteinase Inhibitor 9)

    Jiuru Sun;Lisa Ooms;Catherina H. Bird;Vivien R. Sutton

  • Control of granzymes by serpins.

    Dion Kaiserman;Phillip Ian Bird

Frequent Co-Authors

James C. Whisstock
James C. Whisstock Monash University
Joseph A. Trapani
Joseph A. Trapani Peter MacCallum Cancer Centre
Stephen P. Bottomley
Stephen P. Bottomley Monash University
Ilia Voskoboinik
Ilia Voskoboinik Peter MacCallum Cancer Centre
Robert N. Pike
Robert N. Pike La Trobe University
Nigel J. Waterhouse
Nigel J. Waterhouse QIMR Berghofer Medical Research Institute
Guy S. Salvesen
Guy S. Salvesen Sanford Burnham Prebys Medical Discovery Institute
Ricky W. Johnstone
Ricky W. Johnstone Peter MacCallum Cancer Centre
Gary A. Silverman
Gary A. Silverman Washington University in St. Louis
Eileen Remold-O'Donnell
Eileen Remold-O'Donnell Harvard University

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