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2025

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Best Female Scientists

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118
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611
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Immunology

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119
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Research.com Recognitions

  • 2025 - Research.com Best Female Scientists Award
  • 2020 - Member of the National Academy of Sciences
  • 2018 - Fellow of the American Association for the Advancement of Science (AAAS)
  • 2008 - Fellow of the American Academy of Arts and Sciences

Overview

Judy Lieberman is affiliated with Boston Children's Hospital in the United States. Their research focuses on molecular biology, immunology, infectious diseases, neurology, and public health. The main fields of study include biochemistry, genetics and molecular biology, medicine, and immunology and microbiology.

Their work covers several prominent topics, such as:

  • Inflammasome and immune disorders
  • Interferon and immune responses
  • Immune cell function and interaction
  • Heme oxygenase-1 and carbon monoxide
  • COVID-19 clinical research studies
  • SARS-CoV-2 and COVID-19 research
  • Immune response and inflammation

Recent influential papers authored or coauthored by Lieberman include:

  • "Gasdermin E suppresses tumour growth by activating anti-tumour immunity," 2020, published in Nature
  • "FDA-approved disulfiram inhibits pyroptosis by blocking gasdermin D pore formation," 2020, published in Nature Immunology
  • "Channelling inflammation: gasdermins in physiology and disease," 2021, published in Nature Reviews Drug Discovery
  • "FcγR-mediated SARS-CoV-2 infection of monocytes activates inflammation," 2022, published in Nature
  • "Gasdermin D pore structure reveals preferential release of mature interleukin-1," 2021, published in Nature

Frequent coauthors include:

  • Hao Wu
  • Zhibin Zhang
  • Xing Liu
  • Caroline Junqueira
  • Ying Zhang

Their work has been published in multiple venues with notable frequency, including:

  • Nature
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Proceedings of the National Academy of Sciences
  • Science Immunology
  • Cancer Immunology Research

Judy Lieberman has been recognized with several awards, including:

  • Member of the National Academy of Sciences (2020)
  • Fellow of the American Association for the Advancement of Science (AAAS) (2018)
  • Fellow of the American Academy of Arts and Sciences (2008)

Best Publications

  • Inflammasome-activated gasdermin D causes pyroptosis by forming membrane pores

    Xing Liu;Zhibin Zhang;Zhibin Zhang;Jianbin Ruan;Jianbin Ruan;Youdong Pan

  • let-7 Regulates Self Renewal and Tumorigenicity of Breast Cancer Cells

    Fengyan Yu;Fengyan Yu;Herui Yao;Pengcheng Zhu;Xiaoqin Zhang

  • Identification of Host Proteins Required for HIV Infection Through a Functional Genomic Screen

    Abraham L. Brass;Derek M. Dykxhoorn;Yair Benita;Nan Yan

  • RNA interference targeting Fas protects mice from fulminant hepatitis

    Erwei Song;Sang-Kyung Lee;Jie Wang;Nedim Ince

  • Gasdermin E suppresses tumour growth by activating anti-tumour immunity.

    Zhibin Zhang;Zhibin Zhang;Ying Zhang;Ying Zhang;Shiyu Xia;Shiyu Xia;Qing Kong

  • Interfering with disease: a progress report on siRNA-based therapeutics.

    Antonin de Fougerolles;Hans Peter Vornlocher;John Maraganore;Judy Lieberman

  • Antibody mediated in vivo delivery of small interfering RNAs via cell-surface receptors

    Erwei Song;Pengcheng Zhu;Sang Kyung Lee;Dipanjan Chowdhury

  • siRNA-directed inhibition of HIV-1 infection.

    Carl D. Novina;Michael F. Murray;Derek M. Dykxhoorn;Paul J. Beresford

  • Coding-Independent Regulation of the Tumor Suppressor PTEN by Competing Endogenous mRNAs

    Yvonne Tay;Lev Kats;Leonardo Salmena;Dror Weiss

  • The ABCs of granule-mediated cytotoxicity: new weapons in the arsenal

    Judy Lieberman

  • FDA-approved disulfiram inhibits pyroptosis by blocking gasdermin D pore formation

    Jun Jacob Hu;Jun Jacob Hu;Xing Liu;Xing Liu;Xing Liu;Shiyu Xia;Shiyu Xia;Zhibin Zhang;Zhibin Zhang

  • Knocking down disease: a progress report on siRNA therapeutics.

    Anders Wittrup;Judy Lieberman

  • Death by a thousand cuts: granzyme pathways of programmed cell death.

    Dipanjan Chowdhury;Judy Lieberman

  • FcγR-mediated SARS-CoV-2 infection of monocytes activates inflammation

    Unknown

  • Mutations in the gene encoding the 3'-5' DNA exonuclease TREX1 are associated with systemic lupus erythematosus.

    Min Ae Lee-Kirsch;Maolian Gong;Dipanjan Chowdhury;Lydia Senenko

  • γ-H2AX Dephosphorylation by Protein Phosphatase 2A Facilitates DNA Double-Strand Break Repair

    Dipanjan Chowdhury;Michael-Christopher Keogh;Haruhiko Ishii;Craig L. Peterson

  • Channelling inflammation: gasdermins in physiology and disease.

    Xing Liu;Shiyu Xia;Shiyu Xia;Zhibin Zhang;Zhibin Zhang;Hao Wu;Hao Wu

  • miR-24 Inhibits Cell Proliferation by Targeting E2F2, MYC, and Other Cell-Cycle Genes via Binding to “Seedless” 3′UTR MicroRNA Recognition Elements

    Ashish Lal;Francisco Navarro;Christopher A. Maher;Laura E. Maliszewski

  • Tumor suppressor NM23-H1 is a granzyme A-activated DNase during CTL-mediated apoptosis, and the nucleosome assembly protein SET is its inhibitor.

    Zusen Fan;Paul J. Beresford;David Y. Oh;Dong Zhang

  • Visualizing lipid-formulated siRNA release from endosomes and target gene knockdown

    Anders Wittrup;Angela Ai;Xing Liu;Peter Hamar

  • Desperately seeking microRNA targets.

    Marshall Thomas;Judy Lieberman;Ashish Lal;Ashish Lal

  • A phosphatase complex that dephosphorylates γH2AX regulates DNA damage checkpoint recovery

    Michael Christopher Keogh;Jung Ae Kim;Michael Downey;Jeffrey Fillingham

  • The cytosolic exonuclease TREX1 inhibits the innate immune response to human immunodeficiency virus type 1

    Nan Yan;Ashton D Regalado-Magdos;Bart Stiggelbout;Min Ae Lee-Kirsch

Frequent Co-Authors

Hao Wu
Hao Wu Harvard University
Ashish Lal
Ashish Lal National Institutes of Health
Dipanjan Chowdhury
Dipanjan Chowdhury Harvard University
Erwei Song
Erwei Song Sun Yat-sen University
Tomas Kirchhausen
Tomas Kirchhausen Boston Children's Hospital
Ricardo T. Gazzinelli
Ricardo T. Gazzinelli Universidade Federal de Minas Gerais
Winston Hide
Winston Hide Harvard Medical School
Akiko Hata
Akiko Hata University of California, San Francisco
Bruce D. Walker
Bruce D. Walker Harvard University
Bing Lim
Bing Lim Thymmune Therapeutics

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