H-Index & Metrics Top Publications

H-Index & Metrics

Discipline name H-index Citations Publications World Ranking National Ranking
Immunology H-index 96 Citations 35,909 367 World Ranking 316 National Ranking 1
Medicine H-index 105 Citations 41,251 406 World Ranking 2962 National Ranking 3

Research.com Recognitions

Awards & Achievements

2010 - Fellow, The World Academy of Sciences

2004 - Fellow of John Simon Guggenheim Memorial Foundation

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • Immune system
  • Cytokine

His primary areas of study are Immunology, Toxoplasma gondii, Immune system, Trypanosoma cruzi and Virology. His research investigates the link between Immunology and topics such as Interleukin 12 that cross with problems in Interleukin. The various areas that he examines in his Toxoplasma gondii study include Tumor necrosis factor alpha, CD8, Molecular biology, Spleen and In vivo.

His research in Immune system intersects with topics in Antibody and Microbiology. He interconnects Chemokine, Chagas disease, Interleukin 4, Proinflammatory cytokine and Parasitemia in the investigation of issues within Trypanosoma cruzi. His Virology research integrates issues from Leishmaniasis and DNA.

His most cited work include:

  • Interleukin 12 acts directly on CD4+ T cells to enhance priming for interferon gamma production and diminishes interleukin 4 inhibition of such priming (908 citations)
  • In the absence of endogenous IL-10, mice acutely infected with Toxoplasma gondii succumb to a lethal immune response dependent on CD4+ T cells and accompanied by overproduction of IL-12, IFN-gamma and TNF-alpha. (778 citations)
  • Interleukin 12 is required for the T-lymphocyte-independent induction of interferon gamma by an intracellular parasite and induces resistance in T-cell-deficient hosts (711 citations)

What are the main themes of his work throughout his whole career to date?

His main research concerns Immunology, Virology, Immune system, Trypanosoma cruzi and Antigen. Toxoplasma gondii, Cytokine, CD8, Innate immune system and Antibody are the subjects of his Immunology studies. His research integrates issues of Epitope, Immunization and Recombinant DNA in his study of Virology.

His research in Immune system focuses on subjects like Cell biology, which are connected to Receptor. His Trypanosoma cruzi research also works with subjects such as

  • Chagas disease which is related to area like Pathogenesis,
  • Microbiology together with Proinflammatory cytokine and Virulence. His study looks at the relationship between Antigen and topics such as Leishmaniasis, which overlap with Leishmania.

He most often published in these fields:

  • Immunology (88.40%)
  • Virology (75.00%)
  • Immune system (51.60%)

What were the highlights of his more recent work (between 2015-2021)?

  • Immunology (88.40%)
  • Virology (75.00%)
  • Antigen (41.40%)

In recent papers he was focusing on the following fields of study:

His primary areas of investigation include Immunology, Virology, Antigen, Immune system and Cytotoxic T cell. His research on Virology often connects related areas such as Leishmania infantum. His Antigen study combines topics from a wide range of disciplines, such as Visceral leishmaniasis, Gastroenterology, Molecular biology, Internal medicine and Parasitemia.

The Immune system study combines topics in areas such as Trypanosoma cruzi, Antibody and Plasmodium falciparum. His biological study spans a wide range of topics, including Transcriptome, Microbiology, Chagas disease, Epitope and Virulence. His research on Cytotoxic T cell also deals with topics like

  • CD8 and related T cell and Spleen,
  • CXCR3 which is related to area like Effector.

Between 2015 and 2021, his most popular works were:

  • Guidelines for the use of flow cytometry and cell sorting in immunological studies (second edition) (345 citations)
  • Guidelines for the use of flow cytometry and cell sorting in immunological studies (second edition) (345 citations)
  • Killer lymphocytes use granulysin, perforin and granzymes to kill intracellular parasites (96 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • Immune system
  • DNA

Ricardo T. Gazzinelli spends much of his time researching Immunology, Virology, CD8, Granzyme and Innate immune system. His Immune system and CCR4 investigations are all subjects of Immunology research. His study in Immune system is interdisciplinary in nature, drawing from both Epitope, Leishmania infantum, Leishmania and Cutaneous leishmaniasis.

His Virology research incorporates themes from Microbiology, Plasmodium vivax, Naive B cell, Antibody and Virulence. His work carried out in the field of CD8 brings together such families of science as Spleen, Receptor, Lung injury and Plasmodium berghei. His Innate immune system research is multidisciplinary, relying on both Plasmodium falciparum, Malaria, Hemozoin and Immunity.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Top Publications

In the absence of endogenous IL-10, mice acutely infected with Toxoplasma gondii succumb to a lethal immune response dependent on CD4+ T cells and accompanied by overproduction of IL-12, IFN-gamma and TNF-alpha.

Ricardo T. Gazzinelli;M. Wysocka;S Hieny;T Scharton-Kersten.
Journal of Immunology (1996)

1228 Citations

Interleukin 12 acts directly on CD4+ T cells to enhance priming for interferon gamma production and diminishes interleukin 4 inhibition of such priming

Robert A. Seder;Ricardo Gazzinelli;Alan Sher;William E. Paul.
Proceedings of the National Academy of Sciences of the United States of America (1993)

1030 Citations

Regulation and Function of T-Cell-Mediated Immunity during Toxoplasma gondii Infection

Eric Y. Denkers;Ricardo T. Gazzinelli.
Clinical Microbiology Reviews (1998)

904 Citations

Interleukin 12 is required for the T-lymphocyte-independent induction of interferon gamma by an intracellular parasite and induces resistance in T-cell-deficient hosts.

Ricardo T. Gazzinelli;Sara Hieny;Thomas A. Wynn;Stanley Wolf.
Proceedings of the National Academy of Sciences of the United States of America (1993)

859 Citations

IL-10 inhibits parasite killing and nitrogen oxide production by IFN-gamma-activated macrophages.

R T Gazzinelli;I P Oswald;S L James;A Sher.
Journal of Immunology (1992)

847 Citations

Parasite-induced IL-12 stimulates early IFN-gamma synthesis and resistance during acute infection with Toxoplasma gondii.

R T Gazzinelli;M Wysocka;S Hayashi;E Y Denkers.
Journal of Immunology (1994)

752 Citations

Activation of Toll-like receptor-2 by glycosylphosphatidylinositol anchors from a protozoan parasite.

Marco A. S. Campos;Igor C. Almeida;Osamu Takeuchi;Shizuo Akira.
Journal of Immunology (2001)

700 Citations

Synergistic role of CD4+ and CD8+ T lymphocytes in IFN-gamma production and protective immunity induced by an attenuated Toxoplasma gondii vaccine.

R T Gazzinelli;F T Hakim;S Hieny;G M Shearer.
Journal of Immunology (1991)

680 Citations

Malaria hemozoin is immunologically inert but radically enhances innate responses by presenting malaria DNA to Toll-like receptor 9.

Peggy Parroche;Fanny N. Lauw;Nadege Goutagny;Eicke Latz.
Proceedings of the National Academy of Sciences of the United States of America (2007)

618 Citations

The microbicidal activity of interferon‐γ‐treated macrophages against Trypanosoma cruzi involves an L‐arginine‐dependent, nitrogen oxide‐mediated mechanism inhibitable by interleukin‐10 and transforming growth factor‐β

Ricardo T. Gazzinelli;Isabel P. Oswald;Sara Hieny;Stephanie L. James.
European Journal of Immunology (1992)

607 Citations

Profile was last updated on December 6th, 2021.
Research.com Ranking is based on data retrieved from the Microsoft Academic Graph (MAG).
The ranking h-index is inferred from publications deemed to belong to the considered discipline.

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