What is he best known for?
The fields of study he is best known for:
- Gene
- Immune system
- Internal medicine
João Santana da Silva spends much of his time researching Immunology, Chemokine, Cytokine, Trypanosoma cruzi and Immune system.
His Immunology research is multidisciplinary, incorporating perspectives in Periodontitis, Nitric oxide and Microbiology.
His Chemokine research is multidisciplinary, relying on both Proinflammatory cytokine and CCL5.
João Santana da Silva has included themes like Interferon, Matrix metalloproteinase and Leukocyte migration in his Cytokine study.
His Trypanosoma cruzi research is multidisciplinary, incorporating elements of In vitro, Macrophage, Chagas disease, Virology and In vivo.
His research in Immune system intersects with topics in Interleukin 12, Rhipicephalus sanguineus and Saliva.
His most cited work include:
- A cascade of cytokines mediates mechanical inflammatory hypernociception in mice (468 citations)
- Nitric oxide is involved in control of Trypanosoma cruzi-induced parasitemia and directly kills the parasite in vitro. (334 citations)
- Interleukin 10 and interferon gamma regulation of experimental Trypanosoma cruzi infection. (312 citations)
What are the main themes of his work throughout his whole career to date?
Immunology, Immune system, Trypanosoma cruzi, Chemokine and Cytokine are his primary areas of study.
His study ties his expertise on Microbiology together with the subject of Immunology.
The concepts of his Immune system study are interwoven with issues in Proinflammatory cytokine and Saliva.
As a part of the same scientific family, João Santana da Silva mostly works in the field of Trypanosoma cruzi, focusing on Chagas disease and, on occasion, Myocarditis.
His study with Chemokine involves better knowledge in Receptor.
His study in Interleukin 10 and Interferon gamma falls under the purview of Cytokine.
He most often published in these fields:
- Immunology (54.55%)
- Immune system (25.86%)
- Trypanosoma cruzi (19.60%)
What were the highlights of his more recent work (between 2017-2021)?
- Immunology (54.55%)
- Immune system (25.86%)
- Internal medicine (9.90%)
In recent papers he was focusing on the following fields of study:
João Santana da Silva mainly investigates Immunology, Immune system, Internal medicine, Inflammasome and Gut flora.
His studies deal with areas such as Cell migration and Asymptomatic as well as Immunology.
His Immune system research focuses on Inflammation and how it connects with Spleen.
As part of the same scientific family, he usually focuses on Internal medicine, concentrating on Endocrinology and intersecting with Mesenteric lymph nodes.
His Inflammasome research also works with subjects such as
- Cell biology that connect with fields like Proinflammatory cytokine,
- Paracoccidioides brasiliensis, which have a strong connection to NLRC4, Nitric oxide synthase 2, Cytotoxic T cell and Cytokine.
He focuses mostly in the field of Chagas disease, narrowing it down to matters related to Cardiomyopathy and, in some cases, Trypanosoma cruzi.
Between 2017 and 2021, his most popular works were:
- CEMiTool: a Bioconductor package for performing comprehensive modular co-expression analyses. (63 citations)
- Comparison of different histological indexes in the assessment of UC activity and their accuracy regarding endoscopic outcomes and faecal calprotectin levels (54 citations)
- T cell immunity to Zika virus targets immunodominant epitopes that show cross-reactivity with other Flaviviruses (32 citations)
In his most recent research, the most cited papers focused on:
- Gene
- Internal medicine
- Immune system
João Santana da Silva focuses on Immunology, Internal medicine, Immune system, Inflammasome and Endocrinology.
His Immunology research includes elements of Trypanosoma cruzi and STAT protein.
João Santana da Silva has researched Trypanosoma cruzi in several fields, including Cardiomyopathy, Downregulation and upregulation, Signal transduction, Protozoan infection and Heart disease.
His study in Immune system is interdisciplinary in nature, drawing from both Inflammation, Proinflammatory cytokine, Kidney and Macrophage.
He interconnects NLRC5, NLRP1, Immunopathology and Cutaneous leishmaniasis in the investigation of issues within Inflammasome.
João Santana da Silva combines subjects such as Acute kidney injury and Macrophage polarization with his study of Endocrinology.
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