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Immunology
Brazil
2026

D-Index & Metrics

Immunology

D-Index
99
Citations
29114
World Ranking
764
National Ranking
4

Medicine

D-Index
99
Citations
29801
World Ranking
8696
National Ranking
21

Research.com Recognitions

  • 2026 - Research.com Immunology in Brazil Leader Award
  • 2025 - Research.com Immunology in Brazil Leader Award
  • 2023 - Research.com Immunology in Brazil Leader Award
  • 2022 - Research.com Immunology in Brazil Leader Award

Overview

João S. Silva is affiliated with the Universidade de São Paulo in Brazil. Their primary research field is Medicine, with a focus on epidemiology, infectious diseases, molecular biology, public health, and immunology. The scientist's work covers diverse topics including Trypanosoma species research, leishmaniasis studies, SARS-CoV-2 and COVID-19 research, parasite-host interactions, gut microbiota and health, as well as long-term effects of COVID-19.

Recent publications by João S. Silva include:

  • Prevalence and risk factors for delirium in critically ill patients with COVID-19 (COVID-D): a multicentre cohort study, 2021, The Lancet Respiratory Medicine
  • Recurrent COVID-19 including evidence of reinfection and enhanced severity in thirty Brazilian healthcare workers, 2021, Journal of Infection
  • Mitochondrial DNA Promotes NLRP3 Inflammasome Activation and Contributes to Endothelial Dysfunction and Inflammation in Type 1 Diabetes, 2020, Frontiers in Physiology
  • Arginase and its mechanisms in Leishmania persistence, 2020, Parasite Immunology
  • NLR and Intestinal Dysbiosis-Associated Inflammatory Illness: Drivers or Dampers?, 2020, Frontiers in Immunology

The scientist frequently publishes research in a number of specific venues, including:

  • Frontiers in Immunology
  • SSRN Electronic Journal
  • PLoS Neglected Tropical Diseases
  • Frontiers in Cardiovascular Medicine
  • bioRxiv (Cold Spring Harbor Laboratory)

João S. Silva collaborates with multiple co-authors, notably:

  • Roque Pacheco de Almeida
  • Daniela Carlos
  • Amélia Ribeiro de Jesus
  • Rita C. Tostes
  • Vanessa Carregaro

The scientist's research touches on key topics that contribute to understanding infectious and immunological diseases, with significant attention to COVID-19-related clinical studies and parasitology. Their interdisciplinary approach spans clinical and molecular investigations, public health concerns, and detailed studies on parasite biology and host interactions.

Best Publications

  • A cascade of cytokines mediates mechanical inflammatory hypernociception in mice.

    T. M. Cunha;W. A. Verri;J. S. Silva;S. Poole

  • An Overview of the Modulatory Effects of Oleic Acid in Health and Disease

    Helioswilton Sales-Campos;Patricia Reis de Souza;Bethanea Crema Peghini;Joao Santana da Silva

  • Chemokines in Oral Inflammatory Diseases: Apical Periodontitis and Periodontal Disease

    T.A. Silva;G.P. Garlet;S.Y. Fukada;J.S. Silva

  • Nitric oxide is involved in control of Trypanosoma cruzi-induced parasitemia and directly kills the parasite in vitro.

    G N R Vespa;Fernando de Queiroz Cunha;João Santana da Silva

  • Interleukin 10 and interferon gamma regulation of experimental Trypanosoma cruzi infection.

    J S Silva;P J Morrissey;K H Grabstein;K M Mohler

  • Cytokine expression pattern in compression and tension sides of the periodontal ligament during orthodontic tooth movement in humans

    Thiago P. Garlet;Ulisses Coelho;João S. Silva;Gustavo P. Garlet

  • Regulation of Trypanosoma cruzi infections in vitro and in vivo by transforming growth factor beta (TGF-beta).

    J S Silva;D R Twardzik;S G Reed

  • Inflammasome-derived IL-1β production induces nitric oxide-mediated resistance to Leishmania.

    Djalma S Lima-Junior;Diego L Costa;Vanessa Carregaro;Larissa D Cunha

  • Tumor necrosis factor alpha mediates resistance to Trypanosoma cruzi infection in mice by inducing nitric oxide production in infected gamma interferon-activated macrophages.

    J. S. Silva;G. N. R. Vespa;M. A. G. Cardoso;J. C. S. Aliberti

  • Evidence of the presence of T helper type 17 cells in chronic lesions of human periodontal disease.

    C. R. Cardoso;G. P. Garlet;G. E. Crippa;A. L. Rosa

  • Interleukin-12 mediates resistance to Trypanosoma cruzi in mice and is produced by murine macrophages in response to live trypomastigotes.

    J C Aliberti;M A Cardoso;G A Martins;R T Gazzinelli

  • Patterns of chemokines and chemokine receptors expression in different forms of human periodontal disease.

    Gustavo P. Garlet;Walter Martins;Beatriz R. Ferreira;Cristiane M. Milanezi

  • Regulation of chemokine receptor by Toll-like receptor 2 is critical to neutrophil migration and resistance to polymicrobial sepsis

    Jose C. Alves-Filho;Andressa Freitas;Fabricio O. Souto;Fernando Spiller

  • Regulation of Trypanosoma cruzi infection in mice by gamma interferon and interleukin 10: role of NK cells

    F Cardillo;J C Voltarelli;S G Reed;J S Silva

  • CEMiTool: a Bioconductor package for performing comprehensive modular co-expression analyses.

    Pedro S. T. Russo;Gustavo R. Ferreira;Lucas Esteves Cardozo;Matheus C. Bürger

  • IL-33 induces neutrophil migration in rheumatoid arthritis and is a target of anti-TNF therapy

    Waldiceu A Verri;Fabrício O Souto;Silvio M Vieira;Sergio C L Almeida

  • Trypanosoma cruzi-infected cardiomyocytes produce chemokines and cytokines that trigger potent nitric oxide-dependent trypanocidal activity

    Fabiana Simão Machado;Gislâine Aparecida Martins;Júlio César Soares Aliberti;Fabiola Leslie Antunes Cardoso Mestriner

  • Matrix metalloproteinases, their physiological inhibitors and osteoclast factors are differentially regulated by the cytokine profile in human periodontal disease

    Gustavo P. Garlet;Walter Martins;Benedito A.L. Fonseca;Beatriz R. Ferreira

  • Chemokines, inflammation and Trypanosoma cruzi infection.

    Mauro M. Teixeira;Ricardo T. Gazzinelli;João S. Silva

  • IL-10 mediates susceptibility to Trypanosoma cruzi infection.

    S G Reed;C E Brownell;D M Russo;João Santana da Silva

Frequent Co-Authors

Fernando Q. Cunha
Fernando Q. Cunha Universidade de São Paulo
Gustavo Pompermaier Garlet
Gustavo Pompermaier Garlet Universidade de São Paulo
Julio Aliberti
Julio Aliberti National Institute of Allergy and Infectious Diseases
Ricardo T. Gazzinelli
Ricardo T. Gazzinelli Universidade Federal de Minas Gerais
Mauro M. Teixeira
Mauro M. Teixeira Universidade Federal de Minas Gerais
Dario S. Zamboni
Dario S. Zamboni Universidade de São Paulo
Manoel Barral-Netto
Manoel Barral-Netto Oswaldo Cruz Foundation
Cláudia Brodskyn
Cláudia Brodskyn Oswaldo Cruz Foundation
Aldina Barral
Aldina Barral Oswaldo Cruz Foundation
José C. Alves-Filho
José C. Alves-Filho Universidade de São Paulo

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