2026 Howard M. Lederman: Immunology Researcher – H-Index, Publications & Awards

Discipline name	D-Index	World Ranking	Current World Ranking	National Ranking	Current National Ranking	Publications	Citations
Immunology	44	4753	4397	2136	1957	153	10431

Overview

Howard M. Lederman is affiliated with Johns Hopkins University in the United States. Their research spans multiple fields with a strong focus on biochemistry, genetics, molecular biology, and medicine. Within these broad areas, Lederman's work specializes in molecular biology, immunology, cancer research, pulmonary and respiratory medicine, and infectious diseases.

The primary scientific topics addressed in Lederman's research include DNA repair mechanisms, carcinogens and genotoxicity assessment, immunodeficiency and autoimmune disorders, genetic neurodegenerative diseases, radiation therapy and dosimetry, as well as SARS-CoV-2 and COVID-19 research. This range reflects a multidisciplinary approach to understanding disease mechanisms at genetic and molecular levels, particularly related to immune function and genetic disorders.

Lederman has contributed to several peer-reviewed papers in notable journals, including the following recent publications:

"DNA methylation and gene expression signatures are associated with ataxia-telangiectasia phenotype," 2020, Scientific Reports
"Multidisciplinary Management of Ataxia Telangiectasia: Current Perspectives," 2021, Journal of Multidisciplinary Healthcare
"Combination Therapy With Casirivimab/Imdevimab and Remdesivir for Protracted SARS-CoV-2 Infection in B-cell-Depleted Patients," 2022, Open Forum Infectious Diseases
"Pharmacokinetics of high-titer anti-SARS-CoV-2 human convalescent plasma in high-risk children," 2021, JCI Insight
"Safety and efficacy of intra-erythrocyte dexamethasone sodium phosphate in children with ataxia telangiectasia (ATTeST): a multicentre, randomised, double-blind, placebo-controlled phase 3 trial," 2024, The Lancet Neurology

Frequent collaborators include Sharon A. McGrath-Morrow, Jennifer Wright, Valerie Natale, Cynthia Rothblum-Oviatt, and Thomas O. Crawford. These professional associations highlight ongoing partnerships in the fields of immunology and clinical research related to rare diseases and genetic disorders.

Lederman publishes regularly in several specialized journals with repeated contributions to the Journal of Allergy and Clinical Immunology, Orphanet Journal of Rare Diseases, Clinical Immunology, Journal of Clinical Immunology, and Research Square. This indicates a consistent engagement with communities focused on immunology, rare disease research, and clinical applications.

Best Publications

JM2, encoding a fork head–related protein, is mutated in X-linked autoimmunity–allergic disregulation syndrome

Talal A. Chatila;Frank Blaeser;Nga Ho;Howard M. Lederman

1167
Citations
Ataxia telangiectasia: a review

Cynthia Rothblum-Oviatt;Jennifer Wright;Maureen A. Lefton-Greif;Sharon A. McGrath-Morrow

691
Citations
X-linked agammaglobulinemia: report on a United States registry of 201 patients.

Jerry A. Winkelstein;Mary C. Marino;Howard M. Lederman;Stacie M. Jones

639
Citations
X-linked agammaglobulinemia: an analysis of 96 patients.

Howard M. Lederman;Jerry A. Winkelstein

578
Citations
An essential role for BLNK in human B cell development.

Yoshiyuki Minegishi;Jurg Rohrer;Elaine Coustan-Smith;Howard M. Lederman

457
Citations
Inhibition of antigen-induced lymphocyte proliferation by Tat protein from HIV-1

Raphael P. Viscidi;Kumudini Mayur;Howard M. Lederman;Alan D. Frankel

428
Citations
Gastrointestinal tract pathology in patients with common variable immunodeficiency (CVID): a clinicopathologic study and review.

Jason A. Daniels;Howard M. Lederman;Anirban Maitra;Elizabeth A. Montgomery

403
Citations
Immunodeficiency and infections in ataxia-telangiectasia.

Anna Nowak-Wegrzyn;Thomas O Crawford;Jerry A Winkelstein;Kathryn A Carson

373
Citations
Sarcoidosis and common variable immunodeficiency. Report of 8 cases and review of the literature.

Mary Beth Fasano;Kathleen E. Sullivan;Kathleen E. Sullivan;Sampson B. Sarpong;Sampson B. Sarpong;Robert A. Wood

321
Citations
Response to immunization with recall and neoantigens after prolonged administration of an HIV-1 protease inhibitor-containing regimen

Hernan Valdez;Kimberly Y. Smith;Alan Landay;Elizabeth Connick

225
Citations
Overview of Infections in the Immunocompromised Host.

Lesia K. Dropulic;Howard M. Lederman

225
Citations
Increased susceptibility to mycoplasma infection in patients with hypogammaglobulinemia

Chaim M. Roifman;C. Pandu Rao;Howard M. Lederman;Sasson Lavi

218
Citations
Survival probability in ataxia telangiectasia

Thomas O. Crawford;R. L. Skolasky;R. Fernandez;K. J. Rosquist

185
Citations
Recommendations for live viral and bacterial vaccines in immunodeficient patients and their close contacts

William T. Shearer;Thomas A. Fleisher;Rebecca H. Buckley;Zuhair Ballas

162
Citations
Brief report: hepatic dysfunction as a complication of adenosine deaminase deficiency.

Mary E. Bollinger;Francisco X. Arredondo-Vega;Ines Santisteban;Kathleen Schwarz

157
Citations
Adenosine Deaminase Deficiency in Adults

Hulya Ozsahin;Francisco X. Arredondo-Vega;Ines Santisteban;Hanspeter Fuhrer

144
Citations
Safety and immunogenicity of heptavalent pneumococcal vaccine conjugated to CRM197 among infants with sickle cell disease

Katherine L. O'Brien;Andrea J. Swift;Jerry A. Winkelstein;Mathuram Santosham

138
Citations
Ataxia-telangiectasia (A-T): An emerging dimension of premature ageing.

Yosef Shiloh;Howard M. Lederman

135
Citations
Incomplete Immune Reconstitution after Initiation of Highly Active Antiretroviral Therapy in Human Immunodeficiency Virus–Infected Patients with Severe CD4+ Cell Depletion

Howard M. Lederman;Paige L. Williams;Julia W. Wu;Thomas G. Evans

133
Citations
Cryptosporidiosis Stimulates an Inflammatory Intestinal Response in Malnourished Haitian Children

Beth D. Kirkpatrick;Michelle M. Daniels;Simone Sonia Jean;Jean W. Pape

132
Citations

Frequent Co-Authors

Jerry A. Winkelstein Johns Hopkins University School of Medicine

Anna Nowak-Wegrzyn New York University

Kathleen E. Sullivan Children's Hospital of Philadelphia

Paige L. Williams Harvard University

Bradley A. Warady Children's Mercy Hospital

Michael S. Hershfield Duke University

J. Allen McCutchan University of California, San Diego

Judith S. Currier University of California, Los Angeles

Diane R. Gold Harvard University

Mary Ellen Conley Rockefeller University

External Links

Personal website of Howard M. Lederman

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