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José C. Alves-Filho

José C. Alves-Filho

D-Index & Metrics

Immunology

D-Index
64
Citations
15446
World Ranking
2926
National Ranking
18

Overview

José C. Alves-Filho is affiliated with the Universidade de São Paulo in Brazil and has contributed extensively to the fields of Medicine, Immunology and Microbiology, and Biochemistry, Genetics and Molecular Biology. Their research portfolio includes a strong focus on Immunology, Molecular Biology, Infectious Diseases, Neurology, and Physiology.

The scientist's work centers on several key topics, including COVID-19 Clinical Research Studies, Neutrophil, Myeloperoxidase and Oxidative Mechanisms, Inflammasome and immune disorders, Immune Response and Inflammation, Long-Term Effects of COVID-19, Psoriasis: Treatment and Pathogenesis, and Immune cells in cancer.

José C. Alves-Filho has published papers in a variety of respected venues. These frequent publication venues include:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Cell Reports
  • International Immunopharmacology
  • The Journal of Experimental Medicine
  • Proceedings of the National Academy of Sciences

Their recent papers cover important topics related to COVID-19 and immunological mechanisms. Notable publications include:

  • SARS-CoV-2-triggered neutrophil extracellular traps mediate COVID-19 pathology, 2020, The Journal of Experimental Medicine
  • Inflammasomes are activated in response to SARS-CoV-2 infection and are associated with COVID-19 severity in patients, 2020, The Journal of Experimental Medicine
  • Morphological, cellular, and molecular basis of brain infection in COVID-19 patients, 2022, Proceedings of the National Academy of Sciences
  • PKM2 promotes Th17 cell differentiation and autoimmune inflammation by fine-tuning STAT3 activation, 2020, The Journal of Experimental Medicine
  • Beneficial effects of colchicine for moderate to severe COVID-19: a randomised, double-blinded, placebo-controlled clinical trial, 2021, RMD Open

José C. Alves-Filho collaborates regularly with several co-authors. Frequent collaborators include:

  • Fernando Q. Cunha
  • Thiago M. Cunha
  • Flávio P. Veras
  • Daniele C. Nascimento
  • Paulo Louzada-Júnior

Best Publications

  • SARS-CoV-2-triggered neutrophil extracellular traps mediate COVID-19 pathology.

    Flavio Protasio Veras;Marjorie Cornejo Pontelli;Camila Meirelles Silva;Juliana E Toller-Kawahisa

  • Inflammasomes are activated in response to SARS-CoV-2 infection and are associated with COVID-19 severity in patients.

    Tamara S. Rodrigues;Keyla S.G. De Sá;Adriene Y. Ishimoto;Amanda Becerra

  • Interleukin-33 attenuates sepsis by enhancing neutrophil influx to the site of infection

    Jose C Alves-Filho;Fabiane Sônego;Fabricio O Souto;Andressa Freitas

  • Paclitaxel Reduces Tumor Growth by Reprogramming Tumor-Associated Macrophages to an M1 Profile in a TLR4-Dependent Manner

    Carlos W Wanderley;Carlos W Wanderley;David F Colon;Joao Paulo Mesquita Luiz;Francisco F Oliveira;Francisco F Oliveira

  • Neutrophil Extracellular Traps Induce Organ Damage during Experimental and Clinical Sepsis

    Paula Giselle Czaikoski;José Maurício Segundo Correia Mota;Daniele Carvalho Nascimento;Fabiane Sônego

  • Regulation of chemokine receptor by Toll-like receptor 2 is critical to neutrophil migration and resistance to polymicrobial sepsis

    Jose C. Alves-Filho;Andressa Freitas;Fabricio O. Souto;Fernando Spiller

  • IL-33 attenuates EAE by suppressing IL-17 and IFN-γ production and inducing alternatively activated macrophages.

    Hui-Rong Jiang;Marija Milovanović;Debbie Allan;Wanda Niedbala

  • IL-33 induces neutrophil migration in rheumatoid arthritis and is a target of anti-TNF therapy

    Waldiceu A Verri;Fabrício O Souto;Silvio M Vieira;Sergio C L Almeida

  • Neutrophil paralysis in sepsis.

    José C. Alves-Filho;Fernando Spiller;Fernando Q. Cunha

  • THE ROLE OF NEUTROPHILS IN SEVERE SEPSIS

    José C. Alves-Filho;Andressa de Freitas;Fernando Spiller;Fabrício O. Souto

  • PKM2 promotes Th17 cell differentiation and autoimmune inflammation by fine-tuning STAT3 activation

    Luis Eduardo Alves Damasceno;Douglas Silva Prado;Flavio Protasio Veras;Miriam M. Fonseca

  • Paradoxical Roles of the Neutrophil in Sepsis: Protective and Deleterious.

    Fabiane Sônego;Fernanda Vargas e Silva Castanheira;Raphael Gomes Ferreira;Alexandre Kanashiro

  • IL-33 contributes to sepsis-induced long-term immunosuppression by expanding the regulatory T cell population

    Daniele C. Nascimento;Paulo H. Melo;Annie R. Piñeros;Raphael G. Ferreira

  • Gasdermin D inhibition prevents multiple organ dysfunction during sepsis by blocking NET formation.

    Camila Meirelles Silva;Carlos W S Wanderley;Flavio P Veras;Fabiane Sonego

  • Beneficial effects of colchicine for moderate to severe COVID-19: a randomised, double-blinded, placebo-controlled clinical trial.

    Maria Isabel Lopes;Leticia P Bonjorno;Marcela C Giannini;Natalia B Amaral

  • IL-33 induces skin inflammation with mast cell and neutrophil activation

    Axel J. Hueber;Jose C. Alves-Filho;Darren L. Asquith;Chesney Michels

  • Down-regulation of CXCR2 on Neutrophils in Severe Sepsis Is Mediated by Inducible Nitric Oxide Synthase–derived Nitric Oxide

    Fabrício Rios-Santos;José C. Alves-Filho;Fabrício Oliveira Souto;Fernando Spiller

  • Essential Role of CCR2 in Neutrophil Tissue Infiltration and Multiple Organ Dysfunction in Sepsis

    Fabricio O. Souto;José C. Alves-Filho;Walter M. Turato;Maria Auxiliadora-Martins

  • Spinal cord oligodendrocyte-derived alarmin IL-33 mediates neuropathic pain.

    Ana C. Zarpelon;Francielle C. Rodrigues;Alexandre H. Lopes;Guilherme R. Souza

  • Toll-like receptor 4 signaling leads to neutrophil migration impairment in polymicrobial sepsis.

    José C. Alves-Filho;Andressa de Freitas;Momtchilo Russo;Fernando Q. Cunha

  • Heme oxygenase/carbon monoxide‐biliverdin pathway down regulates neutrophil rolling, adhesion and migration in acute inflammation

    A Freitas;J C Alves-Filho;D D Secco;A F Neto

  • Impaired neutrophil chemotaxis in sepsis associates with GRK expression and inhibition of actin assembly and tyrosine phosphorylation

    Sandra Mara A. Arraes;Sandra Mara A. Arraes;Marta S. Freitas;Marta S. Freitas;Simone V. da Silva;Simone V. da Silva;Heitor A. de Paula Neto;Heitor A. de Paula Neto

Frequent Co-Authors

Fernando Q. Cunha
Fernando Q. Cunha Universidade de São Paulo
Thiago M. Cunha
Thiago M. Cunha Universidade de São Paulo
Foo Y. Liew
Foo Y. Liew University of Glasgow
Dario S. Zamboni
Dario S. Zamboni Universidade de São Paulo
Mauro M. Teixeira
Mauro M. Teixeira Universidade Federal de Minas Gerais
João S. Silva
João S. Silva Universidade de São Paulo
Bernhard Ryffel
Bernhard Ryffel University of Orléans
Damo Xu
Damo Xu University of Glasgow
Norberto Peporine Lopes
Norberto Peporine Lopes Universidade de São Paulo
Danielle G. Souza
Danielle G. Souza Universidade Federal de Minas Gerais

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Related Online Degrees & Career Pathways

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