Timothy R. Zacharewski

Overview

Best Publications

• Purification, cloning, and RXR identity of the HeLa cell factor with which RAR or TR heterodimerizes to bind target sequences efficiently

  Mark Leid;Mark Leid;Philippe Kastner;Philippe Kastner;Ruth Lyons;Ruth Lyons;Harikrishna Nakshatri;Harikrishna Nakshatri

  1428
  Citations

• Bisphenol A interacts with the estrogen receptor α in a distinct manner from estradiol

  Janet C. Gould;Linda S. Leonard;Susan C. Maness;Brandee L. Wagner

  604
  Citations

• NTP Center for the Evaluation of Risks to Human Reproduction: phthalates expert panel report on the reproductive and developmental toxicity of di-n-butyl phthalate ☆

  Robert Kavlock;Kim Boekelheide;Robert Chapin;Michael Cunningham

  588
  Citations

• In vitro and in vivo interactions of bisphenol A and its metabolite, bisphenol A glucuronide, with estrogen receptors alpha and beta.

  Jason B. Matthews;Ken Twomey;Timothy R. Zacharewski

  554
  Citations

• Overview of a workshop on screening methods for detecting potential (anti‐) estrogenic/androgenic chemicals in wildlife

  Gerald T. Ankley;Ellen Mihaich;Ralph G. Stahl;Donald E. Tillitt

  447
  Citations

• 2,3,7,8‐Tetrachlorodibenzo‐p‐dioxin (TCDD) and Related Compounds as Antioestrogens: Characterization and Mechanism of Action

  S. Safe;B. Astroff;M. Harris;T. Zacharewski

  399
  Citations

• Differential estrogen receptor binding of estrogenic substances: a species comparison.

  Jason Matthews;Trine Celius;Robert Halgren;Tim Zacharewski

  377
  Citations

• Hydroxylated polychlorinated biphenyls (PCBs) as estrogens and antiestrogens: structure-activity relationships.

  K. Connor;K. Ramamoorthy;M. Moore;M. Mustain

  342
  Citations

• Endocrine Screening Methods Workshop report: detection of estrogenic and androgenic hormonal and antihormonal activity for chemicals that act via receptor or steroidogenic enzyme mechanisms.

  L.Earl Gray;William R. Kelce;Tom Wiese;Rochelle Tyl

  256
  Citations

• Activity of Benzo[a]pyrene and Its Hydroxylated Metabolites in an Estrogen Receptor-α Reporter Gene Assay

  Grantley D. Charles;Michael J. Bartels;Timothy R. Zacharewski;B. Bhaskar Gollapudi

  233
  Citations

• Antiestrogenic activity of hydroxylated polychlorinated biphenyl congeners identified in human serum.

  M Moore;M Mustain;K Daniel;I Chen

  228
  Citations

• Temporal and Dose-Dependent Hepatic Gene Expression Patterns in Mice Provide New Insights into TCDD-Mediated Hepatotoxicity

  Darrell R. Boverhof;Lyle D. Burgoon;Colleen Tashiro;Brock Chittim

  225
  Citations

• Challenges and Limitations of Gene Expression Profiling in Mechanistic and Predictive Toxicology

  Mark R. Fielden;Tim R. Zacharewski

  222
  Citations

• Exoestrogens: Mechanisms of action and strategies for identification and assessment

  Bradley E. Gillesby;Timothy R. Zacharewski;Timothy R. Zacharewski

  214
  Citations

• Comparative toxicogenomic analysis of the hepatotoxic effects of TCDD in Sprague Dawley rats and C57BL/6 mice.

  Darrell R. Boverhof;Lyle D. Burgoon;Colleen Tashiro;Bonnie Sharratt

  208
  Citations

• NTP center for the evaluation of risks to human reproduction

  Robert Kavlock;Kim Boekelheide;Robert Chapin;Michael Cunningham

  193
  Citations

• Toxicogenomics in risk assessment : Applications and needs

  Darrell R. Boverhof;Timothy R. Zacharewski

  189
  Citations

• Naringenin: a weakly estrogenic bioflavonoid that exhibits antiestrogenic activity

  Mary F. Ruh;Timothy Zacharewski;Kevin Connor;James Howell

  184
  Citations

• Aroclor 1254 as a 2,3,7,8-tetrachlorodibenzo-p-dioxin antagonist: Effects on enzyme induction and immunotoxicity

  R. Bannister;D. Davis;T. Zacharewski;I. Tizard

  168
  Citations

• Failure of chloro-S-triazine-derived compounds to induce estrogen receptor-mediated responses in vivo and in vitro.

  K. Connor;J. Howell;I. Chen;H. Liu

  165
  Citations