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Carole L. Yauk

Carole L. Yauk

D-Index & Metrics

Biology and Biochemistry

D-Index
66
Citations
12346
World Ranking
8865
National Ranking
307

Overview

Carole L. Yauk is affiliated with the University of Ottawa in Canada. Their research focuses primarily on biochemistry, genetics, and molecular biology, with a substantial number of publications in related subfields such as molecular biology, cancer research, health toxicology and mutagenesis, radiology, nuclear medicine and imaging, and computational theory and mathematics.

The scientist's work encompasses a range of topics within molecular biology and toxicology, including carcinogens and genotoxicity assessment, molecular biology techniques and applications, DNA repair mechanisms, the effects and risks of endocrine disrupting chemicals, cancer genomics and diagnostics, computational drug discovery methods, and gene expression and cancer classification.

Recent publications by Carole L. Yauk include:

  • High-Throughput Transcriptomic Analysis of Human Primary Hepatocyte Spheroids Exposed to Per- and Polyfluoroalkyl Substances as a Platform for Relative Potency Characterization, 2021, Toxicological Sciences
  • Potency Ranking of Per- and Polyfluoroalkyl Substances Using High-Throughput Transcriptomic Analysis of Human Liver Spheroids, 2021, Toxicological Sciences
  • Progress towards an OECD reporting framework for transcriptomics and metabolomics in regulatory toxicology, 2021, Regulatory Toxicology and Pharmacology
  • A Transformative Vision for an Omics-Based Regulatory Chemical Testing Paradigm, 2022, Toxicological Sciences
  • R-ODAF: Omics data analysis framework for regulatory application, 2022, Regulatory Toxicology and Pharmacology

The researcher frequently collaborates with Andrew Williams, Matthew J. Meier, Francesco Marchetti, Vinita Chauhan, and Jesse J. Salk, reflecting a network of ongoing partnerships in their field.

Publication venues where Carole L. Yauk has contributed multiple articles include:

  • Environmental and Molecular Mutagenesis
  • Toxicological Sciences
  • International Journal of Radiation Biology
  • Archives of Toxicology
  • bioRxiv (Cold Spring Harbor Laboratory)

Best Publications

  • Germ-line mutations, DNA damage, and global hypermethylation in mice exposed to particulate air pollution in an urban/industrial location

    Carole Yauk;Aris Polyzos;Andrea Rowan-Carroll;Christopher M. Somers

  • Comprehensive comparison of six microarray technologies

    Carole L. Yauk;M. Lynn Berndt;Andrew Williams;George R. Douglas

  • Toxicity Testing in the 21st Century: Progress in the Past Decade and Future Perspectives

    D. Krewski;M. E. Andersen;M. G. Tyshenko;K. Krishnan

  • Incorporating New Technologies Into Toxicity Testing and Risk Assessment: Moving From 21st Century Vision to a Data-Driven Framework

    Russell S. Thomas;Martin A. Philbert;Scott S. Auerbach;Barbara A. Wetmore

  • Air pollution induces heritable DNA mutations.

    Christopher M. Somers;Carole L. Yauk;Paul A. White;Craig L. J. Parfett

  • Carbon black nanoparticle instillation induces sustained inflammation and genotoxicity in mouse lung and liver

    Julie A Bourdon;Anne T Saber;Nicklas R Jacobsen;Keld A Jensen

  • Pulmonary Response to Surface-Coated Nanotitanium Dioxide Particles Includes Induction of Acute Phase Response Genes, Inflammatory Cascades, and Changes in MicroRNAs: A Toxicogenomic Study

    Sabina Halappanavar;Petra Jackson;Andrew Williams;Keld A. Jensen

  • Recommended approaches in the application of toxicogenomics to derive points of departure for chemical risk assessment

    Reza Farmahin;Andrew Williams;Byron Kuo;Nikolai L. Chepelev

  • MWCNTs of different physicochemical properties cause similar inflammatory responses, but differences in transcriptional and histological markers of fibrosis in mouse lungs.

    Sarah S. Poulsen;Anne T. Saber;Andrew Williams;Ole Andersen

  • BMDExpress 2: enhanced transcriptomic dose-response analysis workflow.

    Jason R Phillips;Daniel L Svoboda;Arpit Tandon;Shyam Patel

  • Comparison of toxicogenomics and traditional approaches to inform mode of action and points of departure in human health risk assessment of benzo[a]pyrene in drinking water

    Ivy Moffat;Nikolai L. Chepelev;Sarah Labib;Julie Bourdon-Lacombe

  • Nano-risk Science: application of toxicogenomics in an adverse outcome pathway framework for risk assessment of multi-walled carbon nanotubes

    Sarah Labib;Andrew Williams;Carole L. Yauk;Jake K. Nikota

  • Multilocus DNA fingerprinting reveals high rate of heritable genetic mutation in herring gulls nesting in an industrialized urban site

    Carole L. Yauk;James S. Quinn

  • Hepatic and Pulmonary Toxicogenomic Profiles in Mice Intratracheally Instilled With Carbon Black Nanoparticles Reveal Pulmonary Inflammation, Acute Phase Response, and Alterations in Lipid Homeostasis

    Julie A. Bourdon;Sabina Halappanavar;Anne T. Saber;Nicklas R. Jacobsen

  • Particle-induced pulmonary acute phase response may be the causal link between particle inhalation and cardiovascular disease.

    Anne T. Saber;Nicklas R. Jacobsen;Petra Jackson;Sarah Søs Poulsen

  • Mainstream tobacco smoke causes paternal germ-line DNA mutation.

    Carole L. Yauk;M. Lynn Berndt;Andrew Williams;Andrea Rowan-Carroll

  • Applying 'omics technologies in chemicals risk assessment:: Report of an ECETOC workshop

    Roland Buesen;Brian N Chorley;Beatriz da Silva Lima;George P. Daston

  • The challenge of the application of 'omics technologies in chemicals risk assessment: Background and outlook.

    Ursula G. Sauer;Lize Deferme;Laura Gribaldo;Jörg Hackermüller

  • A novel single molecule analysis of spontaneous and radiation-induced mutation at a mouse tandem repeat locus

    Carole L. Yauk;Yuri E. Dubrova;Gemma R. Grant;Alec J. Jeffreys

  • Transcriptomic Analysis Reveals Novel Mechanistic Insight into Murine Biological Responses to Multi-Walled Carbon Nanotubes in Lungs and Cultured Lung Epithelial Cells

    Sarah Søs Poulsen;Nicklas R. Jacobsen;Sarah Labib;Dongmei Wu

Frequent Co-Authors

Ulla Vogel
Ulla Vogel Technical University of Denmark
Håkan Wallin
Håkan Wallin National Institute of Occupational Health
Albert J. Fornace
Albert J. Fornace Georgetown University
Roger W. L. Godschalk
Roger W. L. Godschalk Maastricht University
Martin R. Stämpfli
Martin R. Stämpfli McMaster University
David M. DeMarini
David M. DeMarini Environmental Protection Agency
Charles Wood
Charles Wood University of Nebraska–Lincoln
Volker M. Arlt
Volker M. Arlt King's College London
Frederik J. van Schooten
Frederik J. van Schooten Maastricht University
David H. Phillips
David H. Phillips King's College London

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