D-Index & Metrics Best Publications
Molecular Biology
USA
2023

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Molecular Biology D-index 124 Citations 53,127 401 World Ranking 133 National Ranking 89

Research.com Recognitions

Awards & Achievements

2023 - Research.com Molecular Biology in United States Leader Award

2020 - Fellow, National Academy of Inventors

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • DNA
  • Cancer

Albert J. Fornace spends much of his time researching Molecular biology, Cell biology, DNA damage, Gene and Cancer research. His studies in Molecular biology integrate themes in fields like Cell culture, Gadd45, Complementary DNA, Tumor suppressor gene and Kinase. He interconnects CHEK1 and Genotoxic Stress in the investigation of issues within Cell biology.

His work in DNA damage tackles topics such as DNA repair which are related to areas like Proliferating cell nuclear antigen. His studies deal with areas such as Cell cycle checkpoint, Cell cycle, Apoptosis, Cancer cell and Regulation of gene expression as well as Cancer research. His Cell cycle research includes themes of Ataxia-telangiectasia and Cell growth.

His most cited work include:

  • A mammalian cell cycle checkpoint pathway utilizing p53 and GADD45 is defective in ataxia-telangiectasia (2773 citations)
  • An Information-Intensive Approach to the Molecular Pharmacology of Cancer (1049 citations)
  • Interaction of the p53-regulated protein Gadd45 with proliferating cell nuclear antigen. (843 citations)

What are the main themes of his work throughout his whole career to date?

His main research concerns Molecular biology, Cancer research, DNA damage, Cell biology and Metabolomics. In his research on the topic of Molecular biology, Regulation of gene expression is strongly related with Gene expression. His studies in Cancer research integrate themes in fields like Carcinogenesis, Cancer, Colorectal cancer, Tumor suppressor gene and Apoptosis.

His research ties DNA repair and DNA damage together. In his work, Cell growth is strongly intertwined with Cell cycle, which is a subfield of Cell biology. Albert J. Fornace works mostly in the field of Metabolomics, limiting it down to concerns involving Ionizing radiation and, occasionally, Pharmacology, Bioinformatics and Immunology.

He most often published in these fields:

  • Molecular biology (31.01%)
  • Cancer research (24.47%)
  • DNA damage (20.46%)

What were the highlights of his more recent work (between 2012-2021)?

  • Metabolomics (19.62%)
  • Cancer research (24.47%)
  • Ionizing radiation (15.19%)

In recent papers he was focusing on the following fields of study:

Albert J. Fornace focuses on Metabolomics, Cancer research, Ionizing radiation, Biodosimetry and Urine. His research integrates issues of Biochemistry and Lipidomics in his study of Metabolomics. Albert J. Fornace has included themes like Cancer, Colorectal cancer, 3,3'-Diindolylmethane, Relative biological effectiveness and Radiation therapy in his Cancer research study.

As a part of the same scientific family, he mostly works in the field of Radiation therapy, focusing on Immune system and, on occasion, Cell biology. The study incorporates disciplines such as DNA damage, Carnitine, Metabolite, Acute Radiation Syndrome and Pharmacology in addition to Ionizing radiation. His DNA damage study frequently draws connections between related disciplines such as DNA repair.

Between 2012 and 2021, his most popular works were:

  • Gadd45 in stress signaling, cell cycle control, and apoptosis. (176 citations)
  • Integrative analysis of the microbiome and metabolome of the human intestinal mucosal surface reveals exquisite inter-relationships (168 citations)
  • Reprograming of gut microbiome energy metabolism by the FUT2 Crohn’s disease risk polymorphism (136 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • DNA
  • Cancer

His primary scientific interests are in Metabolomics, Ionizing radiation, Bioinformatics, Urine and Biodosimetry. His Metabolomics study incorporates themes from High-performance liquid chromatography, Biochemistry, Lipidomics and Fatty acid metabolism. His Ionizing radiation research includes themes of Glycolysis, Metabolome, Immune system and Pharmacology.

His Bioinformatics research incorporates themes from Cancer research, Gene expression profiling, Genotoxicity, Toxicogenomics and Genomic Biomarker. DNA damage is closely connected to Computational chemistry in his research, which is encompassed under the umbrella topic of Tandem mass spectrometry. His studies deal with areas such as Carcinogenesis and Molecular biology as well as Cell culture.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

A mammalian cell cycle checkpoint pathway utilizing p53 and GADD45 is defective in ataxia-telangiectasia

Michael B. Kastan;Qimin Zhan;Wafik S. El-Deiry.
Cell (1992)

4074 Citations

An Information-Intensive Approach to the Molecular Pharmacology of Cancer

John N. Weinstein;Timothy G. Myers;Patrick M. O'Connor;Stephen H. Friend.
Science (1997)

1394 Citations

Characterization of the p53 Tumor Suppressor Pathway in Cell Lines of the National Cancer Institute Anticancer Drug Screen and Correlations with the Growth-Inhibitory Potency of 123 Anticancer Agents

Patrick M. O'Connor;Joany Jackman;Insoo Bae;Timothy G. Myers.
Cancer Research (1997)

1293 Citations

Interaction of the p53-regulated protein Gadd45 with proliferating cell nuclear antigen.

ML Smith;IT Chen;Q Zhan;I Bae.
Science (1994)

1255 Citations

DNA Repair Pathway Stimulated by the Forkhead Transcription Factor FOXO3a Through the Gadd45 Protein

Hien Tran;Anne Brunet;Jill M. Grenier;Sandeep R. Datta.
Science (2002)

1009 Citations

Mammalian genes coordinately regulated by growth arrest signals and DNA-damaging agents.

A J Fornace;D W Nebert;M C Hollander;J D Luethy.
Molecular and Cellular Biology (1989)

915 Citations

Phosphorylation of human p53 by p38 kinase coordinates N‐terminal phosphorylation and apoptosis in response to UV radiation

Bulavin Dv;Saito S;Hollander Mc;Sakaguchi K;Sakaguchi K.
The EMBO Journal (1999)

852 Citations

Hypoxia induces accumulation of p53 protein, but activation of a G1-phase checkpoint by low-oxygen conditions is independent of p53 status.

T G Graeber;J F Peterson;M Tsai;K Monica.
Molecular and Cellular Biology (1994)

817 Citations

GADD45 induction of a G2/M cell cycle checkpoint

Xin Wei Wang;Qimin Zhan;J. D. Coursen;M. A. Khan.
Proceedings of the National Academy of Sciences of the United States of America (1999)

811 Citations

DNA damage-inducible transcripts in mammalian cells

A J Fornace;I Alamo;M C Hollander.
Proceedings of the National Academy of Sciences of the United States of America (1988)

776 Citations

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