2023 - Research.com Molecular Biology in United States Leader Award
2020 - Fellow, National Academy of Inventors
Albert J. Fornace spends much of his time researching Molecular biology, Cell biology, DNA damage, Gene and Cancer research. His studies in Molecular biology integrate themes in fields like Cell culture, Gadd45, Complementary DNA, Tumor suppressor gene and Kinase. He interconnects CHEK1 and Genotoxic Stress in the investigation of issues within Cell biology.
His work in DNA damage tackles topics such as DNA repair which are related to areas like Proliferating cell nuclear antigen. His studies deal with areas such as Cell cycle checkpoint, Cell cycle, Apoptosis, Cancer cell and Regulation of gene expression as well as Cancer research. His Cell cycle research includes themes of Ataxia-telangiectasia and Cell growth.
His main research concerns Molecular biology, Cancer research, DNA damage, Cell biology and Metabolomics. In his research on the topic of Molecular biology, Regulation of gene expression is strongly related with Gene expression. His studies in Cancer research integrate themes in fields like Carcinogenesis, Cancer, Colorectal cancer, Tumor suppressor gene and Apoptosis.
His research ties DNA repair and DNA damage together. In his work, Cell growth is strongly intertwined with Cell cycle, which is a subfield of Cell biology. Albert J. Fornace works mostly in the field of Metabolomics, limiting it down to concerns involving Ionizing radiation and, occasionally, Pharmacology, Bioinformatics and Immunology.
Albert J. Fornace focuses on Metabolomics, Cancer research, Ionizing radiation, Biodosimetry and Urine. His research integrates issues of Biochemistry and Lipidomics in his study of Metabolomics. Albert J. Fornace has included themes like Cancer, Colorectal cancer, 3,3'-Diindolylmethane, Relative biological effectiveness and Radiation therapy in his Cancer research study.
As a part of the same scientific family, he mostly works in the field of Radiation therapy, focusing on Immune system and, on occasion, Cell biology. The study incorporates disciplines such as DNA damage, Carnitine, Metabolite, Acute Radiation Syndrome and Pharmacology in addition to Ionizing radiation. His DNA damage study frequently draws connections between related disciplines such as DNA repair.
His primary scientific interests are in Metabolomics, Ionizing radiation, Bioinformatics, Urine and Biodosimetry. His Metabolomics study incorporates themes from High-performance liquid chromatography, Biochemistry, Lipidomics and Fatty acid metabolism. His Ionizing radiation research includes themes of Glycolysis, Metabolome, Immune system and Pharmacology.
His Bioinformatics research incorporates themes from Cancer research, Gene expression profiling, Genotoxicity, Toxicogenomics and Genomic Biomarker. DNA damage is closely connected to Computational chemistry in his research, which is encompassed under the umbrella topic of Tandem mass spectrometry. His studies deal with areas such as Carcinogenesis and Molecular biology as well as Cell culture.
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A mammalian cell cycle checkpoint pathway utilizing p53 and GADD45 is defective in ataxia-telangiectasia
Michael B. Kastan;Qimin Zhan;Wafik S. El-Deiry.
Cell (1992)
An Information-Intensive Approach to the Molecular Pharmacology of Cancer
John N. Weinstein;Timothy G. Myers;Patrick M. O'Connor;Stephen H. Friend.
Science (1997)
Characterization of the p53 Tumor Suppressor Pathway in Cell Lines of the National Cancer Institute Anticancer Drug Screen and Correlations with the Growth-Inhibitory Potency of 123 Anticancer Agents
Patrick M. O'Connor;Joany Jackman;Insoo Bae;Timothy G. Myers.
Cancer Research (1997)
Interaction of the p53-regulated protein Gadd45 with proliferating cell nuclear antigen.
ML Smith;IT Chen;Q Zhan;I Bae.
Science (1994)
DNA Repair Pathway Stimulated by the Forkhead Transcription Factor FOXO3a Through the Gadd45 Protein
Hien Tran;Anne Brunet;Jill M. Grenier;Sandeep R. Datta.
Science (2002)
Mammalian genes coordinately regulated by growth arrest signals and DNA-damaging agents.
A J Fornace;D W Nebert;M C Hollander;J D Luethy.
Molecular and Cellular Biology (1989)
Phosphorylation of human p53 by p38 kinase coordinates N‐terminal phosphorylation and apoptosis in response to UV radiation
Bulavin Dv;Saito S;Hollander Mc;Sakaguchi K;Sakaguchi K.
The EMBO Journal (1999)
Hypoxia induces accumulation of p53 protein, but activation of a G1-phase checkpoint by low-oxygen conditions is independent of p53 status.
T G Graeber;J F Peterson;M Tsai;K Monica.
Molecular and Cellular Biology (1994)
GADD45 induction of a G2/M cell cycle checkpoint
Xin Wei Wang;Qimin Zhan;J. D. Coursen;M. A. Khan.
Proceedings of the National Academy of Sciences of the United States of America (1999)
DNA damage-inducible transcripts in mammalian cells
A J Fornace;I Alamo;M C Hollander.
Proceedings of the National Academy of Sciences of the United States of America (1988)
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