World's Best Scientists 2026 revealed!

D-Index & Metrics

Biology and Biochemistry

D-Index
52
Citations
17562
World Ranking
16448
National Ranking
6805

Overview

Patrick M. O'Connor was affiliated with the National Institutes of Health in the United States. Their research focused primarily on Earth and Planetary Sciences, with a strong emphasis on Paleontology, as well as related subfields such as Nature and Landscape Conservation, Global and Planetary Change, Molecular Biology, and Geophysics.

The main topics covered in their work included Paleontology and Evolutionary Biology, Evolution and Paleontology Studies, Amphibian and Reptile Biology, Ichthyology and Marine Biology, Paleontology and Stratigraphy of Fossils, Avian ecology and behavior, and Turtle Biology and Conservation.

They contributed to several recent publications, among which were:

  • Late Cretaceous bird from Madagascar reveals unique development of beaks, 2020, Nature
  • Developmental strategies underlying gigantism and miniaturization in non-avialan theropod dinosaurs, 2023, Science
  • The osteology of the Late Cretaceous paravian Rahonavis ostromi from Madagascar, 2020, Palaeontologia Electronica
  • Postcranial skeletal pneumaticity in non-aquatic neoavians: Insights from accipitrimorphae, 2022, Journal of Anatomy
  • Postcranial Skeletal Pneumaticity in Cuculidae, 2021, Zoology

Frequent co-authors throughout their career included Eric M. Roberts, Matthew C. Lamanna, Julia A. Clarke, Nancy J. Stevens, and Joseph Groenke.

Patrick M. O'Connor regularly published in venues such as MorphoSource Media, Abstracts with programs - Geological Society of America, Cretaceous Research, Nature, and the Journal of Anatomy.

Best Publications

  • An Information-Intensive Approach to the Molecular Pharmacology of Cancer

    John N. Weinstein;Timothy G. Myers;Patrick M. O'Connor;Stephen H. Friend

  • Characterization of the p53 Tumor Suppressor Pathway in Cell Lines of the National Cancer Institute Anticancer Drug Screen and Correlations with the Growth-Inhibitory Potency of 123 Anticancer Agents

    Patrick M. O'Connor;Joany Jackman;Insoo Bae;Timothy G. Myers

  • Interaction of the p53-regulated protein Gadd45 with proliferating cell nuclear antigen.

    ML Smith;IT Chen;Q Zhan;I Bae

  • GADD45 induction of a G2/M cell cycle checkpoint

    Xin Wei Wang;Qimin Zhan;J. D. Coursen;M. A. Khan

  • Nonclinical Antiangiogenesis and Antitumor Activities of Axitinib (AG-013736), an Oral, Potent, and Selective Inhibitor of Vascular Endothelial Growth Factor Receptor Tyrosine Kinases 1, 2, 3

    Dana D. Hu-Lowe;Helen Y. Zou;Maren L. Grazzini;Max E. Hallin

  • The Chk1 protein kinase and the Cdc25C regulatory pathways are targets of the anticancer agent UCN-01

    Paul R. Graves;Lijia Yu;Julie K. Schwarz;Janis Gales

  • Induction of a common pathway of apoptosis by staurosporine

    Richard Bertrand;Eric Solary;Patrick O'Connor;Kurt W. Kohn

  • UCN-01: a Potent Abrogator of G2 Checkpoint Function in Cancer Cells With Disrupted p53

    Qizhi Wang;Saijun Fan;Alan Eastman;Peter J. Worland

  • Wip1, a novel human protein phosphatase that is induced in response to ionizing radiation in a p53-dependent manner

    M Fiscella;H Zhang;S Fan;K Sakaguchi

  • Disruption of p53 function sensitizes breast cancer MCF-7 cells to cisplatin and pentoxifylline

    Fan S;Smith Ml;Rivet Dj nd;Duba D

  • p53 Gene Mutations Are Associated with Decreased Sensitivity of Human Lymphoma Cells to DNA Damaging Agents

    Saijun Fan;Wafik S. El-Deiry;Insoo Bae;Jim Freeman

  • Induction of bax by genotoxic stress in human cells correlates with normal p53 status and apoptosis.

    Qimin Zhan;Sajan Fan;Insoo Bae;C. Guillouf

  • Involvement of the p53 tumor suppressor in repair of u.v.-type DNA damage

    Smith Ml;Chen It;Zhan Q;O'Connor Pm

  • Role of the p53 tumor suppressor gene in cell cycle arrest and radiosensitivity of Burkitt's lymphoma cell lines

    Patrick M. O'Connor;Joany Jackman;Daniel Jondle;Kishor Bhatia

  • Enzymatic Depletion of Tumor Hyaluronan Induces Antitumor Responses in Preclinical Animal Models

    Curtis B. Thompson;H. Michael Shepard;Patrick M. O'Connor;Salam Kadhim

  • Abrogation of an S-phase checkpoint and potentiation of camptothecin cytotoxicity by 7-hydroxystaurosporine (UCN-01) in human cancer cell lines, possibly influenced by p53 function

    Rong Guang Shao;Chun Xia Cao;Tsunehiro Shimizu;Patrick M. O'Connor

  • A p53-independent pathway for activation of WAF1/CIP1 expression following oxidative stress.

    Tommaso Russo;Nicola Zambrano;Franca Esposito;Rosario Ammendola

  • Polo-like Kinase Is a Cell Cycle-regulated Kinase Activated during Mitosis

    Ryoji Hamanaka;Mark R. Smith;Patrick M. O'Connor;Sharon Maloid

  • Cells lacking CIP1/WAF1 genes exhibit preferential sensitivity to cisplatin and nitrogen mustard

    Saijun Fan;Johnny K Chang;Martin L Smith;Diane Duba

  • Unscheduled activation of cyclin B1/Cdc2 kinase in human promyelocytic leukemia cell line HL60 cells undergoing apoptosis induced by DNA damage.

    Tsunehiro Shimizu;Patrick M. O'Connor;Kurt W. Kohn;Yves Pommier

Frequent Co-Authors

Kurt W. Kohn
Kurt W. Kohn National Institutes of Health
Albert J. Fornace
Albert J. Fornace Georgetown University
Qimin Zhan
Qimin Zhan Peking University Stomatological Hospital
Yves Pommier
Yves Pommier National Institutes of Health
Stephen H. Friend
Stephen H. Friend Sage Bionetworks
John N. Weinstein
John N. Weinstein The University of Texas MD Anderson Cancer Center
Timothy G. Myers
Timothy G. Myers National Institutes of Health
Peter P. Roller
Peter P. Roller National Institutes of Health
Dominic A. Scudiero
Dominic A. Scudiero Science Applications International Corporation (United States)
William C. Reinhold
William C. Reinhold National Institutes of Health

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