World's Best Scientists 2026 revealed!
Award Badge
Molecular Biology
China
2025

D-Index & Metrics

Molecular Biology

D-Index
83
Citations
28299
World Ranking
896
National Ranking
13

Research.com Recognitions

  • 2025 - Research.com Molecular Biology in China Leader Award
  • 2014 - OSA Fellows Qiwen Zhan University of Dayton, U.S.A. For seminal contributions to the development of new optical polarization engineering techniques for controlling light-matter interactions on the nanometer scale.
  • 2013 - SPIE Fellow

Overview

Qimin Zhan is affiliated with Peking Union Medical College Hospital in China. Their research focuses on biochemistry, genetics, and molecular biology, with significant contributions in medicine. The primary subfields of study reflect an emphasis on molecular biology, cancer research, oncology, surgery, and pulmonary and respiratory medicine.

The scientist's work covers several main topics, including RNA modifications and cancer, cancer-related molecular mechanisms research, esophageal cancer research and treatment, cancer-related gene regulation, circular RNAs in diseases, epigenetics and DNA methylation, and cancer involving hypoxia and metabolism.

Frequent collaborators include Weimin Zhang, Yan Wang, Qingnan Wu, Yongmei Song, and Jinting Li. These coauthors have contributed extensively alongside Zhan, reflecting ongoing collaborative projects.

Key publication venues for Zhan's research are:

  • Signal Transduction and Targeted Therapy
  • Chinese Journal of Cancer Research
  • Nature Communications
  • Medical Review
  • Cancer Research

Selected recent papers illustrate the focus and scope of their research activity:

  • "Liver tumour immune microenvironment subtypes and neutrophil heterogeneity," 2022, Nature
  • "Whole-genome sequencing of 508 patients identifies key molecular features associated with poor prognosis in esophageal squamous cell carcinoma," 2020, Cell Research
  • "Integrated multi-omics profiling yields a clinically relevant molecular classification for esophageal squamous cell carcinoma," 2022, Cancer Cell
  • "Nuclear genome-derived circular RNA circPUM1 localizes in mitochondria and regulates oxidative phosphorylation in esophageal squamous cell carcinoma," 2022, Signal Transduction and Targeted Therapy
  • "Gut microbiota-mediated nucleotide synthesis attenuates the response to neoadjuvant chemoradiotherapy in rectal cancer," 2022, Cancer Cell

Their contributions have earned recognition through awards such as the OSA Fellows in 2014 for contributions to optical polarization engineering techniques and SPIE Fellow status in 2013.

Best Publications

  • A mammalian cell cycle checkpoint pathway utilizing p53 and GADD45 is defective in ataxia-telangiectasia

    Michael B. Kastan;Qimin Zhan;Wafik S. El-Deiry

  • Interaction of the p53-regulated protein Gadd45 with proliferating cell nuclear antigen.

    ML Smith;IT Chen;Q Zhan;I Bae

  • Identification of genomic alterations in oesophageal squamous cell cancer

    Yongmei Song;Lin Li;Yunwei Ou;Zhibo Gao

  • GADD45 induction of a G2/M cell cycle checkpoint

    Xin Wei Wang;Qimin Zhan;J. D. Coursen;M. A. Khan

  • Association with Cdc2 and inhibition of Cdc2/Cyclin B1 kinase activity by the p53-regulated protein Gadd45.

    Qimin Zhan;M. J. Antinore;Xin Wei Wang;F. Carrier;F. Carrier

  • Disruption of p53 function sensitizes breast cancer MCF-7 cells to cisplatin and pentoxifylline

    Fan S;Smith Ml;Rivet Dj nd;Duba D

  • Genomic instability in Gadd45a- deficient mice

    M. C. Hollander;M. S. Sheikh;D. V. Bulavin;K. Lundgren

  • Induction of cellular p53 activity by DNA-damaging agents and growth arrest.

    Qimin Zhan;F. Carrier;A. J. Fornace

  • The gadd and MyD genes define a novel set of mammalian genes encoding acidic proteins that synergistically suppress cell growth.

    Q Zhan;K A Lord;I Alamo;M C Hollander

  • Induction of bax by genotoxic stress in human cells correlates with normal p53 status and apoptosis.

    Qimin Zhan;Sajan Fan;Insoo Bae;C. Guillouf

  • Involvement of the p53 tumor suppressor in repair of u.v.-type DNA damage

    Smith Ml;Chen It;Zhan Q;O'Connor Pm

  • Interactions between p53 and MDM2 in a mammalian cell cycle checkpoint pathway

    Chaw Yuan Chen;Jonathan D. Oliner;Qimin Zhan;Albert J. Fornace

  • Genomic Analyses Reveal Mutational Signatures and Frequently Altered Genes in Esophageal Squamous Cell Carcinoma

    Ling Zhang;Yong Zhou;Caixia Cheng;Heyang Cui

  • Genome-wide association study identifies three new susceptibility loci for esophageal squamous-cell carcinoma in Chinese populations

    Chen Wu;Zhibin Hu;Zhonghu He;Weihua Jia

  • The p53-dependent γ-Ray Response of GADD45

    Qimin Zhan;Insoo Bae;Michael B. Kastan;Albert J. Fornace

  • Human In vivo Radiation-Induced Biomarkers Gene Expression Changes in Radiotherapy Patients

    Sally A. Amundson;Marcy B. Grace;Christopher B. McLeland;Michael W. Epperly

  • Genome-wide association analyses of esophageal squamous cell carcinoma in Chinese identify multiple susceptibility loci and gene-environment interactions

    Chen Wu;Chen Wu;Peter Kraft;Kan Zhai;Jiang Chang

  • The GADD45 inhibition of Cdc2 kinase correlates with GADD45-mediated growth suppression.

    Shunqian Jin;Michael J. Antinore;Feng-Di T. Lung;Xin Dong

  • ATF3 induction following DNA damage is regulated by distinct signaling pathways and over-expression of ATF3 protein suppresses cells growth.

    Feiyue Fan;Shunqian Jin;Sally A Amundson;Tong Tong

  • Spatial intratumoral heterogeneity and temporal clonal evolution in esophageal squamous cell carcinoma

    Jia-Jie Hao;De-Chen Lin;De-Chen Lin;Huy Q Dinh;Anand Mayakonda

Frequent Co-Authors

Albert J. Fornace
Albert J. Fornace Georgetown University
Yu Zhang
Yu Zhang Peking University
Mingzhou Guo
Mingzhou Guo Chinese PLA General Hospital
James G. Herman
James G. Herman University of Pittsburgh
Patrick M. O'Connor
Patrick M. O'Connor National Institutes of Health
Zhihua Liu
Zhihua Liu Peking Union Medical College Hospital
Dongxin Lin
Dongxin Lin Chinese Academy of Sciences
Chen Wu
Chen Wu Peking Union Medical College Hospital
Chuanyue Wu
Chuanyue Wu University of Pittsburgh
Jiang Chang
Jiang Chang University of Chinese Academy of Sciences

If you think any of the details on this page are incorrect, let us know.

Report an issue

We appreciate your kind effort to assist us to improve this page, it would be helpful providing us with as much detail as possible in the text box below:

Related Online Degrees & Career Pathways

If you're interested in molecular biology, a range of online programs and career pathways can support your goals—whether you’re transitioning from the military, working full-time, or seeking to upskill. Many military friendly colleges online offer flexible degree options tailored for veterans and active-duty personnel, making advanced study in scientific or health-related fields more accessible.

Careers that complement a molecular biology background—such as social work, psychology, or mental health counseling—are now easier to enter with online master’s degrees. If you’re drawn to community support roles, consider enrolling in one of the best online msw programs to gain crucial therapeutic and advocacy skills.

For those interested in understanding human behavior or mental health within a scientific context, the accelerated psychology masters programs and online masters degree in mental health counseling can provide a fast route to specialized roles. Combining molecular biology with these disciplines can expand your career opportunities in research, healthcare, and beyond.

Best Scientists Citing Qimin Zhan

Trending Scientists

Recently Published Articles