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Molecular Biology

D-Index
50
Citations
9966
World Ranking
2559
National Ranking
71

Overview

Mingzhou Guo is affiliated with the Chinese PLA General Hospital in China. Their research primarily focuses on the fields of Biochemistry, Genetics and Molecular Biology, with a specific emphasis on subfields such as Molecular Biology, Cancer Research, Oncology, Pulmonary and Respiratory Medicine, and Epidemiology.

Their recent publication record includes the following papers:

  • "Aberrant NSUN2-mediated m5C modification of H19 lncRNA is associated with poor differentiation of hepatocellular carcinoma," 2020, published in Oncogene
  • "Trends in prevalence and incidence of chronic respiratory diseases from 1990 to 2017," 2020, published in Respiratory Research
  • "Downregulation of the FTO m6A RNA demethylase promotes EMT-mediated progression of epithelial tumors and sensitivity to Wnt inhibitors," 2021, published in Nature Cancer
  • "Synthetic lethality strategies: Beyond BRCA1/2 mutations in pancreatic cancer," 2020, published in Cancer Science
  • "Notch4 mediates vascular remodeling via ERK/JNK/P38 MAPK signaling pathways in hypoxic pulmonary hypertension," 2022, published in Respiratory Research

The main topics covered in their research include:

  • Epigenetics and DNA Methylation
  • Cancer-related molecular mechanisms research
  • Cancer-related gene regulation
  • RNA modifications and cancer
  • Histone Deacetylase Inhibitors Research
  • Circular RNAs in diseases
  • MicroRNA in disease regulation

They frequently publish in the following venues:

  • Cancer Science
  • Epigenomics
  • Respiratory Research
  • Clinical Epigenetics
  • Frontiers in Genetics

Collaborations play a significant role in their work, with frequent co-authors including:

  • Meiying Zhang
  • Aiai Gao
  • James G. Herman
  • Hengmi Cui
  • Xiansheng Liu

Best Publications

  • DNA Methylation Markers and Early Recurrence in Stage I Lung Cancer

    Malcolm V. Brock;Craig M. Hooker;Emi Ota-Machida;Yu Han

  • Aberrant promoter methylation profiles of tumor suppressor genes in hepatocellular carcinoma.

    Bin Yang;Mingzhou Guo;James G. Herman;Douglas P. Clark

  • Recurrently deregulated lncRNAs in hepatocellular carcinoma.

    Yang Yang;Lei Chen;Jin Gu;Hanshuo Zhang

  • Abnormalities of the APC/β-catenin pathway in endometrial cancer

    Gema Moreno-Bueno;David Hardisson;Carolina Sánchez;David Sarrió

  • Molecular characteristics of non-small cell lung cancer

    Unknown

  • Epigenetic and genetic alterations of APC and CDH1 genes in lobular breast cancer: relationships with abnormal E-cadherin and catenin expression and microsatellite instability.

    David Sarrió;Gema Moreno-Bueno;David Hardisson;Carolina Sánchez-Estévez

  • Epigenetic inactivation of the canonical Wnt antagonist SRY-Box containing gene 17 in colorectal cancer

    Wei Zhang;Sabine C. Glöckner;Mingzhou Guo;Emi Ota Machida

  • Long non-coding RNA gadd7 interacts with TDP-43 and regulates Cdk6 mRNA decay.

    Xuefeng Liu;Dan Li;Weimin Zhang;Mingzhou Guo

  • Epigenetic heterogeneity in cancer

    Mingzhou Guo;Mingzhou Guo;Yaojun Peng;Aiai Gao;Chen Du

  • Promoter Hypermethylation of Resected Bronchial Margins: A Field Defect of Changes?

    Mingzhou Guo;Michael G. House;Craig Hooker;Yu Han

  • Long non-coding RNA HOTAIR, a driver of malignancy, predicts negative prognosis and exhibits oncogenic activity in oesophageal squamous cell carcinoma.

    X Li;Z Wu;Q Mei;M Guo

  • Promoter methylation profiles of tumor suppressor genes in intrahepatic and extrahepatic cholangiocarcinoma.

    Bin Yang;Bin Yang;Michael G House;Mingzhou Guo;James G Herman

  • Hypermethylation of the GATA genes in lung cancer.

    Mingzhou Guo;Yoshimitsu Akiyama;Michael G. House;Craig M. Hooker

  • Cancer epigenetics and methylation.

    Manel Esteller;Mario F. Fraga;Maria F. Paz;Elias Campo

  • DNA promoter hypermethylation of p16 and APC predicts neoplastic progression in Barrett's esophagus.

    Jean S Wang;Mingzhou Guo;Elizabeth A Montgomery;Richard E Thompson

  • Accumulation of Promoter Methylation Suggests Epigenetic Progression in Squamous Cell Carcinoma of the Esophagus

    Mingzhou Guo;Jingli Ren;Michael G. House;Yu Qi

  • SOX17 antagonizes WNT/β-catenin signaling pathway in hepatocellular carcinoma.

    Yan Jia;Yunsheng Yang;Shuang Liu;James G. Herman

  • miR-127 regulates cell proliferation and senescence by targeting BCL6.

    Jingwen Chen;Miao Wang;Mingzhou Guo;Yuntao Xie

  • Portraying breast cancers with long noncoding RNAs

    Olivier Van Grembergen;Martin Bizet;Eric James de Bony;Emilie Calonne

  • Frequent inactivation of RAMP2, EFEMP1 and Dutt1 in lung cancer by promoter hypermethylation.

    Wen Yue;Sanja Dacic;Quanhong Sun;Rodney Landreneau

Frequent Co-Authors

James G. Herman
James G. Herman University of Pittsburgh
Qimin Zhan
Qimin Zhan Peking University Stomatological Hospital
Kongming Wu
Kongming Wu Zhengzhou University
François Fuks
François Fuks Université Libre de Bruxelles
Weidong Han
Weidong Han Chinese PLA General Hospital
Runsheng Chen
Runsheng Chen Chinese Academy of Sciences
Michael Q. Zhang
Michael Q. Zhang The University of Texas at Dallas
Fengmin Lu
Fengmin Lu Peking University
James P. Herman
James P. Herman University of Cincinnati
Jin Jen
Jin Jen Bristol Myers Squibb

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