World's Best Scientists 2026 revealed!

D-Index & Metrics

Biology and Biochemistry

D-Index
76
Citations
21073
World Ranking
5042
National Ranking
159

Overview

Weidong Han is affiliated with the Chinese PLA General Hospital in China and has an extensive research portfolio primarily focused on medicine, with significant contributions in biochemistry, genetics, and molecular biology.

The scientist's research spans several subfields, including oncology, immunology, molecular biology, genetics, and pulmonary and respiratory medicine.

Key topics covered in their work include:

  • CAR-T cell therapy research
  • Cancer Immunotherapy and Biomarkers
  • Immune Cell Function and Interaction
  • Lymphoma Diagnosis and Treatment
  • Virus-based gene therapy research
  • Immunotherapy and Immune Responses
  • Nanowire Synthesis and Applications

Weidong Han has published numerous papers, with several notable recent works:

  • "Granzyme A from cytotoxic lymphocytes cleaves GSDMB to trigger pyroptosis in target cells," 2020, Science
  • "Manganese is critical for antitumor immune responses via cGAS-STING and improves the efficacy of clinical immunotherapy," 2020, Cell Research
  • "Temporal single-cell tracing reveals clonal revival and expansion of precursor exhausted T cells during anti-PD-1 therapy in lung cancer," 2021, Nature Cancer
  • "TGF-β inhibition via CRISPR promotes the long-term efficacy of CAR T cells against solid tumors," 2020, JCI Insight
  • "Bispecific CAR-T cells targeting both CD19 and CD22 for therapy of adults with relapsed or refractory B cell acute lymphoblastic leukemia," 2020, Journal of Hematology & Oncology

The scientist frequently contributes to the following publication venues:

  • Journal of Clinical Oncology
  • Blood
  • Cellular and Molecular Immunology
  • Journal of Hematology & Oncology
  • Frontiers in Oncology

Weidong Han collaborates regularly with several co-authors, including:

  • Yao Wang
  • Zhiqiang Wu
  • Qingming Yang
  • Chunmeng Wang
  • Chuan Tong

Best Publications

  • Granzyme A from cytotoxic lymphocytes cleaves GSDMB to trigger pyroptosis in target cells.

    Zhiwei Zhou;Huabin He;Kun Wang;Xuyan Shi

  • LPS-preconditioned mesenchymal stromal cells modify macrophage polarization for resolution of chronic inflammation via exosome-shuttled let-7b

    Dongdong Ti;Haojie Hao;Chuan Tong;Jiejie Liu

  • Manganese is critical for antitumor immune responses via cGAS-STING and improves the efficacy of clinical immunotherapy

    Mengze Lv;Mengze Lv;Meixia Chen;Rui Zhang;Wen Zhang;Wen Zhang

  • Treatment of CD33-directed Chimeric Antigen Receptor-modified T Cells in One Patient With Relapsed and Refractory Acute Myeloid Leukemia

    Quan-shun Wang;Yao Wang;Hai-yan Lv;Qing-wang Han

  • New development in CAR-T cell therapy

    Zhenguang Wang;Zhiqiang Wu;Yang Liu;Weidong Han

  • Autologous T Cells Expressing CD30 Chimeric Antigen Receptors for Relapsed or Refractory Hodgkin Lymphoma: An Open-Label Phase I Trial.

    Chun-Meng Wang;Zhi-Qiang Wu;Yao Wang;Ye-Lei Guo

  • Lessons learned from the blockade of immune checkpoints in cancer immunotherapy

    Xiaolei Li;Xiaolei Li;Changshun Shao;Yufang Shi;Weidong Han

  • Chimeric Antigen Receptors Modified T-Cells for Cancer Therapy.

    Hanren Dai;Yao Wang;Xuechun Lu;Weidong Han

  • Infusion of mesenchymal stem cells ameliorates hyperglycemia in type 2 diabetic rats: identification of a novel role in improving insulin sensitivity.

    Yiling Si;Yali Zhao;Haojie Hao;Jiejie Liu

  • MSCs: Biological characteristics, clinical applications and their outstanding concerns.

    Yi-Ling Si;Ya-Li Zhao;Hao-Jie Hao;Xiao-Bing Fu

  • Chimeric antigen receptor-modified T cells for the immunotherapy of patients with EGFR-expressing advanced relapsed/refractory non-small cell lung cancer

    Kaichao Feng;Yelei Guo;Hanren Dai;Yao Wang

  • Phase I study of chimeric antigen receptor modified T cells in treating HER2-positive advanced biliary tract cancers and pancreatic cancers.

    Kaichao Feng;Yang Liu;Yelei Guo;Jingdan Qiu

  • Bispecific CAR-T cells targeting both CD19 and CD22 for therapy of adults with relapsed or refractory B cell acute lymphoblastic leukemia

    Hanren Dai;Hanren Dai;Zhiqiang Wu;Hejin Jia;Chuan Tong

  • CD133-directed CAR T cells for advanced metastasis malignancies: A phase I trial.

    Yao Wang;Meixia Chen;Zhiqiang Wu;Chuan Tong

  • Optimized tandem CD19/CD20 CAR-engineered T cells in refractory/relapsed B-cell lymphoma.

    Chuan Tong;Yajing Zhang;Yang Liu;Xingyu Ji

  • TGF-β inhibition via CRISPR promotes the long-term efficacy of CAR T cells against solid tumors.

    Na Tang;Chen Cheng;Chen Cheng;Xingying Zhang;Miaomiao Qiao

  • lncRNAs: insights into their function and mechanics in underlying disorders.

    Xiaolei Li;Zhiqiang Wu;Xiaobing Fu;Weidong Han

  • Cocktail treatment with EGFR-specific and CD133-specific chimeric antigen receptor-modified T cells in a patient with advanced cholangiocarcinoma

    Kai-chao Feng;Ye-lei Guo;Yang Liu;Han-ren Dai

  • Phase I Study of Chimeric Antigen Receptor-Modified T Cells in Patients with EGFR-Positive Advanced Biliary Tract Cancers.

    Yelei Guo;Kaichao Feng;Yang Liu;Zhiqiang Wu

  • Genetically engineered T cells for cancer immunotherapy.

    Dan Li;Xue Li;Wei-Lin Zhou;Yong Huang

Frequent Co-Authors

John E.J. Rasko
John E.J. Rasko Centenary Institute of Cancer Medicine and Cell Biology
Mingzhou Guo
Mingzhou Guo Chinese PLA General Hospital
Wanli Liu
Wanli Liu Tsinghua University
Fei Wang
Fei Wang Chinese Academy of Sciences
Yufang Shi
Yufang Shi Soochow University
Fuchu He
Fuchu He Beijing Proteome Research Center
Changshun Shao
Changshun Shao Soochow University
Lin Liu
Lin Liu Chinese Academy of Sciences
Qi-Jing Li
Qi-Jing Li Duke University
François Fuks
François Fuks Université Libre de Bruxelles

If you think any of the details on this page are incorrect, let us know.

Report an issue

We appreciate your kind effort to assist us to improve this page, it would be helpful providing us with as much detail as possible in the text box below:

Best Scientists Citing Weidong Han

Trending Scientists